1SZK
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![BU of 1szk by Molmil](/molmil-images/mine/1szk) | The structure of gamma-aminobutyrate aminotransferase mutant: E211S | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ... | 著者 | Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Fisher, A.J, Toney, M.D. | 登録日 | 2004-04-05 | 公開日 | 2005-03-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Biochemistry, 44, 2005
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1SZL
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![BU of 1szl by Molmil](/molmil-images/mine/1szl) | F-spondin TSR domain 1 | 分子名称: | F-spondin | 著者 | Tossavainen, H, Paakkonen, K, Permi, P, Kilpelainen, I, Guntert, P. | 登録日 | 2004-04-06 | 公開日 | 2005-04-19 | 最終更新日 | 2022-03-02 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structures of the first and fourth TSR domains of F-spondin Proteins, 64, 2006
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1SZM
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![BU of 1szm by Molmil](/molmil-images/mine/1szm) | DUAL BINDING MODE OF BISINDOLYLMALEIMIDE 2 TO PROTEIN KINASE A (PKA) | 分子名称: | 3-(1H-INDOL-3-YL)-4-{1-[2-(1-METHYLPYRROLIDIN-2-YL)ETHYL]-1H-INDOL-3-YL}-1H-PYRROLE-2,5-DIONE, cAMP-dependent protein kinase, alpha-catalytic subunit | 著者 | Gassel, M, Breitenlechner, C.B, Koenig, N, Huber, R, Engh, R.A, Bossemeyer, D. | 登録日 | 2004-04-06 | 公開日 | 2004-06-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The protein kinase C inhibitor bisindolyl maleimide 2 binds with reversed orientations to different conformations of protein kinase a. J.Biol.Chem., 279, 2004
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1SZN
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![BU of 1szn by Molmil](/molmil-images/mine/1szn) | THE STRUCTURE OF ALPHA-GALACTOSIDASE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Golubev, A.M, Nagem, R.A.P, Brando Neto, J.R, Neustroev, K.N, Eneyskaya, E.V, Kulminskaya, A.A, Shabalin, K.A, Savel'ev, A.N, Polikarpov, I. | 登録日 | 2004-04-06 | 公開日 | 2004-08-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Crystal structure of alpha-galactosidase from Trichoderma reesei and its complex with galactose: implications for catalytic mechanism. J.Mol.Biol., 339, 2004
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1SZO
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![BU of 1szo by Molmil](/molmil-images/mine/1szo) | Crystal Structure Analysis of the 6-Oxo Camphor Hydrolase His122Ala Mutant Bound to Its Natural Product (2S,4S)-alpha-Campholinic Acid | 分子名称: | (2S,4S)-4-(2,2-DIHYDROXYETHYL)-2,3,3-TRIMETHYLCYCLOPENTANONE, 6-oxocamphor hydrolase, CALCIUM ION | 著者 | Leonard, P.M, Grogan, G. | 登録日 | 2004-04-06 | 公開日 | 2004-06-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of 6-oxo camphor hydrolase H122A mutant bound to its natural product, (2S,4S)-alpha-campholinic acid: mutant structure suggests an atypical mode of transition state binding for a crotonase homolog. J.Biol.Chem., 279, 2004
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1SZP
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![BU of 1szp by Molmil](/molmil-images/mine/1szp) | A Crystal Structure of the Rad51 Filament | 分子名称: | DNA repair protein RAD51, SULFATE ION | 著者 | Conway, A.B, Lynch, T.W, Zhang, Y, Fortin, G.S, Symington, L.S, Rice, P.A. | 登録日 | 2004-04-06 | 公開日 | 2004-07-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal structure of a Rad51 filament. Nat.Struct.Mol.Biol., 11, 2004
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1SZQ
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![BU of 1szq by Molmil](/molmil-images/mine/1szq) | Crystal Structure of 2-methylcitrate dehydratase | 分子名称: | 2-methylcitrate dehydratase | 著者 | Rajashankar, K.R, Kniewel, R, Solorzano, V, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-04-06 | 公開日 | 2004-04-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of 2-methylcitrate dehydratase To be Published
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1SZR
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![BU of 1szr by Molmil](/molmil-images/mine/1szr) | A Dimer interface mutant of ornithine decarboxylase reveals structure of gem diamine intermediate | 分子名称: | N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N~2~-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-D-ORNITHINE, Ornithine decarboxylase, ... | 著者 | Jackson, L.K, Baldwin, J, Goldsmith, E.J, Phillips, M.A. | 登録日 | 2004-04-06 | 公開日 | 2004-10-26 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase Biochemistry, 43, 2004
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1SZS
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![BU of 1szs by Molmil](/molmil-images/mine/1szs) | The structure of gamma-aminobutyrate aminotransferase mutant: I50Q | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ... | 著者 | Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Zhou, X, Fisher, A.J, Toney, M.D. | 登録日 | 2004-04-06 | 公開日 | 2005-03-01 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Biochemistry, 44, 2005
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1SZT
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1SZU
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![BU of 1szu by Molmil](/molmil-images/mine/1szu) | The structure of gamma-aminobutyrate aminotransferase mutant: V241A | 分子名称: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-aminobutyrate aminotransferase, ... | 著者 | Liu, W, Peterson, P.E, Langston, J.A, Jin, X, Zhou, X, Fisher, A.J, Toney, M.D. | 登録日 | 2004-04-06 | 公開日 | 2005-03-01 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Kinetic and Crystallographic Analysis of Active Site Mutants of Escherichia coligamma-Aminobutyrate Aminotransferase. Biochemistry, 44, 2005
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1SZV
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![BU of 1szv by Molmil](/molmil-images/mine/1szv) | Structure of the Adaptor Protein p14 reveals a Profilin-like Fold with Novel Function | 分子名称: | Late endosomal/lysosomal Mp1 interacting protein | 著者 | Qian, C, Zhang, Q, Wang, X, Zeng, L, Farooq, A, Zhou, M.M. | 登録日 | 2004-04-06 | 公開日 | 2005-03-15 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Adaptor Protein p14 Reveals a Profilin-like Fold with Distinct Function J.Mol.Biol., 347, 2005
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1SZW
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![BU of 1szw by Molmil](/molmil-images/mine/1szw) | |
1SZX
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![BU of 1szx by Molmil](/molmil-images/mine/1szx) | Role Of Hydrogen Bonding In The Active Site Of Human Manganese Superoxide Dismutase | 分子名称: | MANGANESE (II) ION, Superoxide dismutase [Mn], mitochondrial | 著者 | Greenleaf, W.B, Perry, J.J, Hearn, A.S, Cabelli, D.E, Lepock, J.R, Stroupe, M.E, Tainer, J.A, Nick, H.S, Silverman, D.N. | 登録日 | 2004-04-06 | 公開日 | 2004-04-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Role of hydrogen bonding in the active site of human manganese superoxide dismutase. Biochemistry, 43, 2004
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1SZY
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![BU of 1szy by Molmil](/molmil-images/mine/1szy) | |
1SZZ
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![BU of 1szz by Molmil](/molmil-images/mine/1szz) | Crystal structure of peptide deformylase from Leptospira Interrogans complexed with inhibitor actinonin | 分子名称: | ACTINONIN, Peptide deformylase, ZINC ION | 著者 | Zhou, Z, Song, X, Li, Y, Gong, W. | 登録日 | 2004-04-06 | 公開日 | 2005-08-16 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Novel conformational states of peptide deformylase from pathogenic bacterium Leptospira interrogans: implications for population shift J.Biol.Chem., 280, 2005
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1T00
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![BU of 1t00 by Molmil](/molmil-images/mine/1t00) | |
1T01
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![BU of 1t01 by Molmil](/molmil-images/mine/1t01) | Vinculin complexed with the VBS1 helix from talin | 分子名称: | Talin 1, unnamed protein product | 著者 | Papagrigoriou, E, Gingras, A.R, Barsukov, I.L, Critchley, D.R, Emsley, J. | 登録日 | 2004-04-07 | 公開日 | 2004-08-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Activation of a vinculin-binding site in the talin rod involves rearrangement of a five-helix bundle Embo J., 23, 2004
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1T02
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![BU of 1t02 by Molmil](/molmil-images/mine/1t02) | Crystal structure of a Statin bound to class II HMG-CoA reductase | 分子名称: | (3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC ACID, 3-hydroxy-3-methylglutaryl-coenzyme A reductase, SULFATE ION | 著者 | Tabernero, L, Rodwell, V.W, Stauffacher, C. | 登録日 | 2004-04-07 | 公開日 | 2004-08-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a statin bound to a class II hydroxymethylglutaryl-CoA reductase. J.Biol.Chem., 278, 2003
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1T03
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![BU of 1t03 by Molmil](/molmil-images/mine/1t03) | HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer (complex P) | 分子名称: | MAGNESIUM ION, POL polyprotein, Synthetic oligonucleotide primer, ... | 著者 | Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. | 登録日 | 2004-04-07 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structure of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Nat.Struct.Mol.Biol., 11, 2004
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1T04
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![BU of 1t04 by Molmil](/molmil-images/mine/1t04) | Three dimensional structure of a humanized anti-IFN-Gamma Fab in C2 space group | 分子名称: | Huzaf Antibody Heavy Chain, Huzaf Antibody Light Chain | 著者 | Bourne, P.C, Terzyan, S.S, Cloud, G, Landolfi, N.F, Vasquez, M, Edmundson, A.B. | 登録日 | 2004-04-07 | 公開日 | 2004-10-05 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms. Acta Crystallogr.,Sect.D, 60, 2004
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1T05
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![BU of 1t05 by Molmil](/molmil-images/mine/1t05) | HIV-1 reverse transcriptase crosslinked to template-primer with tenofovir-diphosphate bound as the incoming nucleotide substrate | 分子名称: | GLYCEROL, MAGNESIUM ION, POL polyprotein, ... | 著者 | Tuske, S, Sarafianos, S.G, Ding, J, Arnold, E. | 登録日 | 2004-04-07 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of HIV-1 RT-DNA complexes before and after incorporation of the anti-AIDS drug tenofovir Nat.Struct.Mol.Biol., 11, 2004
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1T06
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1T07
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![BU of 1t07 by Molmil](/molmil-images/mine/1t07) | Crystal Structure of Conserved Protein of Unknown Function PA5148 from Pseudomonas aeruginosa | 分子名称: | Hypothetical UPF0269 protein PA5148 | 著者 | Kim, Y, Joachimiak, A, Skarina, T, Savchenko, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2004-04-07 | 公開日 | 2004-08-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of PA5148 from Pseudomonas aeruginosa To be Published
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1T08
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![BU of 1t08 by Molmil](/molmil-images/mine/1t08) | Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3 | 分子名称: | Adenomatous polyposis coli protein, Beta-catenin, Beta-catenin-interacting protein 1 | 著者 | Ha, N.-C, Tonozuka, T, Stamos, J.L, Weis, W.I. | 登録日 | 2004-04-07 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation Mol.Cell, 15, 2004
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