1SZY

Solution structure of ITALY1 ("Initiator tRNA Anticodon Loop from Yeast"), an unmodified 21-nt RNA with the sequence of the anticodon stem-loop of yeast initiator tRNA

Summary for 1SZY

• Entry DOI: 10.2210/pdb1szy/pdb
• Descriptor: 5'-R(P*GP*GP*CP*AP*GP*GP*GP*CP*UP*CP*AP*UP*AP*AP*CP*CP*CP*UP*GP*CP*C)-3' (1 entity in total)
• Functional Keywords: initiator trna anticodon loop, rna
• Total number of polymer chains: 1
• Total formula weight: 6703.05

Authors

Schweisguth, D.C.,Moore, P.B. (deposition date: 2004-04-06, release date: 2004-04-20, Last modification date: 2024-05-29)

Primary citation

Schweisguth, D.C.,Moore, P.B.
On the conformation of the anticodon loops of initiator and elongator methionine tRNAs.
J.Mol.Biol., 267:505-519, 1997

PubMed Abstract: The solution conformations of analogues of initiator and elongator tRNA anticodon stem-loops have been compared by NMR. The data indicate that both have conformations closely similar to those reported for crystalline elongator tRNAs. The two loops differ in their dynamics, however: that of the elongator analogue is more flexible than its initiator counterpart. The anticodon stem-loops of initiator tRNAs are more likely to be distinguished from those of elongator tRNAs during initiation on the basis of their distinctive stem sequences, than they are by differences in the conformations of their anticodon loops.

PubMed: 9126834
DOI: 10.1006/jmbi.1996.0903

Experimental method

SOLUTION NMR