PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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3LOM	CRYSTAL STRUCTURE OF GERANYLTRANSFERASE FROM Legionella pneumophila 分子名称: Geranyltranstransferase, PHOSPHATE ION 著者 Patskovsky, Y, Toro, R, Rutter, M, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2010-02-04 公開日 2010-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Prediction of function for the polyprenyl transferase subgroup in the isoprenoid synthase superfamily. Proc.Natl.Acad.Sci.USA, 110, 2013
3LEA	Crystal structure of the catalytic domain of TACE with Isoindolinone-biphenyl-hydantoin inhibitor 分子名称: 2-{[(4R)-2,5-dioxo-4-(4-pyridin-3-ylphenyl)imidazolidin-4-yl]methyl}-6-methoxy-1-oxo-1H-isoindolium, Disintegrin and metalloproteinase domain-containing protein 17, ISOPROPYL ALCOHOL, ... 著者 Orth, P. 登録日 2010-01-14 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biaryl substituted hydantoin compounds as TACE inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
3LQZ	Crystal Structure of HLA-DP2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ... 著者 Dai, S. 登録日 2010-02-10 公開日 2010-04-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.25 Å) 主引用文献 Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc.Natl.Acad.Sci.USA, 107, 2010
3LGD	Crystal structure of human adenosine deaminase growth factor, adenosine deaminase type 2 (ADA2) 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Adenosine deaminase CECR1, ... 著者 Zavialov, A.V. 登録日 2010-01-20 公開日 2010-02-09 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the growth factor activity of human adenosine deaminase ADA2. J.Biol.Chem., 285, 2010
3LT3	Crystal structure of Rv3671c from M. tuberculosis H37Rv, Ser343Ala mutant, inactive form 分子名称: POSSIBLE MEMBRANE-ASSOCIATED SERINE PROTEASE 著者 Biswas, T, Small, J, Vandal, O, Ehrt, S, Tsodikov, O.V. 登録日 2010-02-14 公開日 2010-11-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insight into serine protease Rv3671c that Protects M. tuberculosis from oxidative and acidic stress. Structure, 18, 2010
5K9O	Crystal structure of multidonor HV1-18+HD3-9 class broadly neutralizing Influenza A antibody 31.b.09 in complex with Hemagglutinin H1 A/California/04/2009 分子名称: 31.b.09 Heavy Fv, 31.b.09 Light Fv, Hemagglutinin, ... 著者 Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D. 登録日 2016-06-01 公開日 2016-12-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.387 Å) 主引用文献 Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses. Cell, 166, 2016
3LUD	Crystal structure of MID domain from hAGO2 in complex with AMP 分子名称: ADENOSINE MONOPHOSPHATE, PHOSPHATE ION, Protein argonaute-2 著者 Frank, F, Sonenberg, N, Nagar, B. 登録日 2010-02-17 公開日 2010-05-26 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.095 Å) 主引用文献 Structural basis for 5'-nucleotide base-specific recognition of guide RNA by human AGO2. Nature, 465, 2010
3LIN	crystal structure of HTLV protease complexed with the inhibitor, KNI-10562 分子名称: N-[(2S,3S)-4-{(4R)-4-[(2,2-dimethylpropyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-3-yl}-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-N~2~-{(2S)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-3-methyl-L-valinamide, Protease 著者 Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. 登録日 2010-01-25 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
1OCQ	COMPLEX OF THE ENDOGLUCANASE CEL5A FROM BACILLUS AGARADHEARANS AT 1.08 ANGSTROM RESOLUTION with cellobio-derived isofagomine 分子名称: 5-HYDROXYMETHYL-3,4-DIHYDROXYPIPERIDINE, ENDOGLUCANASE 5A, GLYCEROL, ... 著者 Varrot, A, Macdonald, J, Stick, R.V, Withers, S.G, Davies, G.J. 登録日 2003-02-09 公開日 2003-06-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Direct Observation of the Protonation State of an Imino Sugar Glycosidase Inhibitor Upon Binding J.Am.Chem.Soc., 125, 2003
3L7U	Crystal structure of human NM23-H1 分子名称: Nucleoside diphosphate kinase A, PHOSPHATE ION 著者 Han, B.G, Min, K, Lee, B.I, Lee, S. 登録日 2009-12-29 公開日 2010-11-10 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Refined Structure of Human NM23-H1 from a Hexagonal Crystal BULL.KOREAN CHEM.SOC., 31, 2010
4P59	HER3 extracellular domain in complex with Fab fragment of MOR09825 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MOR09825 Fab fragment heavy chain, ... 著者 Sprague, E.R. 登録日 2014-03-15 公開日 2014-04-16 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 An antibody that locks HER3 in the inactive conformation inhibits tumor growth driven by HER2 or neuregulin. Cancer Res., 73, 2013
3L6J	Structure of cinaciguat (bay 58-2667) bound to nostoc H-NOX domain 分子名称: 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid, Alr2278 protein 著者 Martin, F, van den Akker, F. 登録日 2009-12-23 公開日 2010-05-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase. J.Biol.Chem., 285, 2010
6UEU	Crystal structure of BF DNA polymerase F710Y mutant bound to tetrahydrofuran and dATP 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*(3DR)P*AP*CP*GP*TP*GP*AP*TP*CP*G)-3'), ... 著者 Wu, E.Y, Beese, L.S. 登録日 2019-09-23 公開日 2020-09-30 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis for blockage of DNA synthesis by a thymine dimer lesion in a high-fidelity DNA polymerase To Be Published
3L8P	Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207 分子名称: 2-methyl-11-(1-methylethyl)-8-[(2S)-tetrahydro-2H-pyran-2-yl]-2,11,12,13-tetrahydro-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one, Angiopoietin-1 receptor 著者 Fedorov, A.A, Fedorov, E.V, Pauletti, D, Meyer, S.L, Hudkins, R.L, Almo, S.C. 登録日 2010-01-03 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207 To be Published
3LAY	Alpha-Helical barrel formed by the decamer of the zinc resistance-associated protein (STM4172) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 分子名称: Zinc resistance-associated protein 著者 Filippova, E.V, Minasov, G, Shuvalova, L, Winsor, J, Dubrovska, I, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-01-07 公開日 2010-01-19 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Alpha-Helical barrel formed by the decamer of the zinc resistance-associated protein (STM4172) from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 To be Published
3LFK	A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators 分子名称: CITRIC ACID, MarR Like Protein, TVG0766549, ... 著者 Liu, Z, Walton, T.A, Rees, D.C. 登録日 2010-01-17 公開日 2010-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A reported archaeal mechanosensitive channel is a structural homolog of MarR-like transcriptional regulators. Protein Sci., 19, 2010
1AFC	STRUCTURAL STUDIES OF THE BINDING OF THE ANTI-ULCER DRUG SUCROSE OCTASULFATE TO ACIDIC FIBROBLAST GROWTH FACTOR 分子名称: 1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose-(2-1)-2,3,4,6-tetra-O-sulfonato-alpha-D-glucopyranose, ACIDIC FIBROBLAST GROWTH FACTOR 著者 Zhu, X, Hsu, B.T, Rees, D.C. 登録日 1993-07-13 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor. Structure, 1, 1993
3LCY	Titin Ig tandem domains A164-A165 分子名称: Titin 著者 Chen, Q, Groves, M.R, Wilmanns, M. 登録日 2010-01-12 公開日 2011-05-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural investigation of the Titin A-band tandem Ig domains A164-A165 To be Published
3LHJ	Crystal Structure of p38a Mitogen-Activated Protein Kinase in Complex with a Pyrazolopyridinone Inhibitor. 分子名称: Mitogen-activated protein kinase 14, N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide 著者 Mohr, C, Jordan, S. 登録日 2010-01-22 公開日 2010-04-14 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.31 Å) 主引用文献 Discovery and evaluation of 7-alkyl-1,5-bis-aryl-pyrazolopyridinones as highly potent, selective, and orally efficacious inhibitors of p38alpha mitogen-activated protein kinase. J.Med.Chem., 53, 2010
3LI0	Crystal structure of the mutant R203A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with inhibitor BMP 分子名称: 1-(5'-PHOSPHO-BETA-D-RIBOFURANOSYL)BARBITURIC ACID, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Wood, B.M, Gerlt, J.A, Almo, S.C. 登録日 2010-01-23 公開日 2010-06-16 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme. Biochemistry, 51, 2012
3LFG	Crystal structure of HPr-C-His from Thermoanaerobacter tengcongensis 分子名称: Phosphotransferase system, HPr-related proteins 著者 Fu, T.M, Su, X.D. 登録日 2010-01-17 公開日 2010-12-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Dimerization of HPr by reversible domain swapping To be Published
3LIQ	Crystal Structure of HTLV protease complexed with the inhibitor, KNI-10673 分子名称: (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-5,5-dimethyl-N-(2-methylpropyl)-1,3-thiazolidine-4-carboxamide, Protease 著者 Satoh, T, Li, M, Nguyen, J, Kiso, Y, Wlodawer, A, Gustchina, A. 登録日 2010-01-25 公開日 2010-07-14 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401, 2010
3LFS	Crystal structure of CDK2 with SAR37, an aminoindazole type inhibitor 分子名称: Cell division protein kinase 2, N-(6-chloro-5-phenyl-1H-indazol-3-yl)butanamide 著者 Dreyer, M.K, Wendt, K.U, Schimanski-Breves, S, Loenze, P. 登録日 2010-01-18 公開日 2010-03-02 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Rational design of potent GSK3beta inhibitors with selectivity for Cdk1 and Cdk2. Bioorg.Med.Chem.Lett., 20, 2010
3LGO	Structure of Gse1p, member of the GSE/EGO complex 分子名称: Protein SLM4 著者 Kogan, K, Fass, D. 登録日 2010-01-21 公開日 2010-08-04 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Structural conservation of components in the amino acid sensing branch of the TOR pathway in yeast and mammals. J.Mol.Biol., 402, 2010
3LJO	Bovine trypsin in complex with UB-THR 11 分子名称: (S)-N-(4-carbamimidoylbenzyl)-1-(2-(cyclohexylamino)ethanoyl)pyrrolidine-2-carboxamide, CALCIUM ION, Cationic trypsin, ... 著者 Wegscheid-Gerlach, C, Heine, A, Klebe, G. 登録日 2010-01-26 公開日 2010-10-06 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Congeneric but still distinct: how closely related trypsin ligands exhibit different thermodynamic and structural properties. J.Mol.Biol., 405, 2011

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