3LIN

crystal structure of HTLV protease complexed with the inhibitor, KNI-10562

Summary for 3LIN

Entry DOI	10.2210/pdb3lin/pdb
Related	2B7F 3LIN 3LIT 3LIV 3LIX 3LIY
Related PRD ID	PRD_000577
Descriptor	Protease, N-[(2S,3S)-4-{(4R)-4-[(2,2-dimethylpropyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-3-yl}-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-N~2~-{(2S)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-3-methyl-L-valinamide (3 entities in total)
Functional Keywords	hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Human T-lymphotropic virus 1
Total number of polymer chains	12
Total formula weight	155070.41
Authors	Satoh, T.,Li, M.,Nguyen, J.,Kiso, Y.,Wlodawer, A.,Gustchina, A. (deposition date: 2010-01-25, release date: 2010-07-14, Last modification date: 2023-09-06)
Primary citation	Satoh, T.,Li, M.,Nguyen, J.T.,Kiso, Y.,Gustchina, A.,Wlodawer, A. Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401:626-641, 2010 Cited by PubMed: 20600105 DOI: 10.1016/j.jmb.2010.06.052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.96 Å)

Structure validation