3LIV

crystal structure of HTLV protease complexed with the inhibitor KNI-10683

Summary for 3LIV

Entry DOI	10.2210/pdb3liv/pdb
Related	2B7F 3LIN 3LIQ 3LIT 3LIX 3LIY
Related PRD ID	PRD_000580
Descriptor	Protease, (4R)-3-[(2S,3S)-3-[[(2S)-2-[[(2S)-2-azanyl-2-phenyl-ethanoyl]amino]-3,3-dimethyl-butanoyl]amino]-2-hydroxy-4-phenyl-but anoyl]-N-[(2R)-3,3-dimethylbutan-2-yl]-5,5-dimethyl-1,3-thiazolidine-4-carboxamide (3 entities in total)
Functional Keywords	hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Human T-lymphotropic virus 1
Total number of polymer chains	2
Total formula weight	25801.06
Authors	Satoh, T.,Li, M.,Nguyen, J.,Kiso, Y.,Wlodawer, A.,Gustchina, A. (deposition date: 2010-01-25, release date: 2010-07-14, Last modification date: 2023-09-06)
Primary citation	Satoh, T.,Li, M.,Nguyen, J.T.,Kiso, Y.,Gustchina, A.,Wlodawer, A. Crystal structures of inhibitor complexes of human T-cell leukemia virus (HTLV-1) protease. J.Mol.Biol., 401:626-641, 2010 Cited by PubMed: 20600105 DOI: 10.1016/j.jmb.2010.06.052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation