3LIN
crystal structure of HTLV protease complexed with the inhibitor, KNI-10562
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Protease | polymer | 116 | 12566.6 | 12 | UniProt (Q82134) Pfam (PF00077) | Human T-lymphotropic virus 1 | |
| 2 | M, N, O, P, Q... (B, C, E, H, I...) | N-[(2S,3S)-4-{(4R)-4-[(2,2-dimethylpropyl)carbamoyl]-5,5-dimethyl-1,3-thiazolidin-3-yl}-3-hydroxy-4-oxo-1-phenylbutan-2-yl]-N~2~-{(2S)-2-[(methoxycarbonyl)amino]-2-phenylacetyl}-3-methyl-L-valinamide | non-polymer | 711.9 | 6 | BIRD (PRD_000577) Chemie (E13) | |||
| 3 | AA, BA, CA, DA, S... (I, J, K, L, A...) | water | water | 18.0 | 785 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 116 (UniProt: Q82134)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 150798.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 4271.5 | |
| All* | Total formula weight | 155070.4 |
