3L6J
Structure of cinaciguat (bay 58-2667) bound to nostoc H-NOX domain
Summary for 3L6J
Entry DOI | 10.2210/pdb3l6j/pdb |
Related | 2O09 2O0C 2O0G |
Descriptor | Alr2278 protein, 4-({(4-carboxybutyl)[2-(2-{[4-(2-phenylethyl)benzyl]oxy}phenyl)ethyl]amino}methyl)benzoic acid (3 entities in total) |
Functional Keywords | guanylyl cyclase, bay58-2667, signaling protein |
Biological source | Nostoc sp. |
Total number of polymer chains | 2 |
Total formula weight | 43558.68 |
Authors | Martin, F.,van den Akker, F. (deposition date: 2009-12-23, release date: 2010-05-12, Last modification date: 2023-09-06) |
Primary citation | Martin, F.,Baskaran, P.,Ma, X.,Dunten, P.W.,Schaefer, M.,Stasch, J.P.,Beuve, A.,van den Akker, F. Structure of cinaciguat (BAY 58-2667) bound to Nostoc H-NOX domain reveals insights into heme-mimetic activation of the soluble guanylyl cyclase. J.Biol.Chem., 285:22651-22657, 2010 Cited by PubMed: 20463019DOI: 10.1074/jbc.M110.111559 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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