PDB: 48062 件ウェブページステータス検索Chemie searchBIRD

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5JJL	Rho transcription termination factor bound to rU8 and 5 ADP-BeF3 molecules 分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Thomsen, N.D, Lawson, M.R, Witkowsky, L.B, Qu, S, Berger, J.M. 登録日 2016-04-24 公開日 2016-11-16 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
5JIR	Crystal structure of Treponema pallidum protein Tp0624 分子名称: CHLORIDE ION, GLYCEROL, OOP family OmpA-OmpF porin 著者 Parker, M.L, Boulanger, M.J. 登録日 2016-04-22 公開日 2016-11-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The Structure of Treponema pallidum Tp0624 Reveals a Modular Assembly of Divergently Functionalized and Previously Uncharacterized Domains. Plos One, 11, 2016
5JLX	AntpHD with 15bp DNA duplex S-monothioated at Cytidine-8 分子名称: DNA (5'-D(*AP*GP*AP*AP*AP*GP*CP*(C7S)P*AP*TP*TP*AP*GP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*CP*TP*AP*AP*TP*GP*GP*CP*TP*TP*TP*C)-3'), Homeotic protein antennapedia, ... 著者 White, M.A, Zandarashvili, L, Iwahara, J, Nguyen, D. 登録日 2016-04-27 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.748 Å) 主引用文献 Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem, 17, 2016
5JM8	The structure of ATP-bound aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Aerobactin synthase IucA, MAGNESIUM ION 著者 Bailey, D.C, Drake, E.J, Gulick, A.M. 登録日 2016-04-28 公開日 2016-06-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae. Biochemistry, 55, 2016
5J6Z	Structure of anastellin bound to beta-strands A and B from the third type III domain of fibronectin 分子名称: Anastellin, Fibronectin 著者 Stine, J.M, Briknarova, K. 登録日 2016-04-05 公開日 2017-04-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 The Interaction between the Third Type III Domain from Fibronectin and Anastellin Involves beta-Strand Exchange. Biochemistry, 56, 2017
5JOE	Crystal structure of I81 from titin 分子名称: 1,2-ETHANEDIOL, ISOPROPYL ALCOHOL, Titin 著者 Fleming, J, Zhou, T, Bogomolovas, J, Labeit, S, Mayans, O. 登録日 2016-05-02 公開日 2016-08-17 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex. Febs Lett., 590, 2016
5JQ3	Crystal structure of Ebola glycoprotein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein 1,Envelope glycoprotein 1,Envelope glycoprotein 1, Envelope glycoprotein 2, ... 著者 Zhao, Y, Ren, J, Stuart, D.I. 登録日 2016-05-04 公開日 2016-06-29 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Toremifene interacts with and destabilizes the Ebola virus glycoprotein. Nature, 535, 2016
5JQY	Aspartyl/Asparaginyl beta-hydroxylase (AspH)oxygenase and TPR domains in complex with manganese, N-oxalylglycine and factor X substrate peptide fragment(39mer-4Ser) 分子名称: ACETATE ION, Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, ... 著者 McDonough, M.A, Pfeffer, I. 登録日 2016-05-05 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Aspartate/asparagine-beta-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nat Commun, 10, 2019
5JZH	Cryo-EM structure of aerolysin prepore 分子名称: Aerolysin 著者 Iacovache, I, Zuber, B. 登録日 2016-05-16 公開日 2016-07-13 最終更新日 2018-10-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Cryo-EM structure of aerolysin variants reveals a novel protein fold and the pore-formation process. Nat Commun, 7, 2016
5K3H	Crystals structure of Acyl-CoA oxidase-1 in Caenorhabditis elegans, Apo form-II 分子名称: Acyl-coenzyme A oxidase 著者 Zhang, X, Li, K, Jones, R.A, Bruner, S.D, Butcher, R.A. 登録日 2016-05-19 公開日 2016-08-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Structural characterization of acyl-CoA oxidases reveals a direct link between pheromone biosynthesis and metabolic state in Caenorhabditis elegans. Proc.Natl.Acad.Sci.USA, 113, 2016
5K55	Human muscle fructose-1,6-bisphosphatase E69Q mutant in active R-state in complex with fructose-6-phosphate 分子名称: 6-O-phosphono-beta-D-fructofuranose, Fructose-1,6-bisphosphatase isozyme 2 著者 Barciszewski, J, Wisniewski, J, Kolodziejczyk, R, Dzugaj, A, Jaskolski, M, Rakus, D. 登録日 2016-05-23 公開日 2017-06-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.977 Å) 主引用文献 Structural studies of human muscle FBPase To Be Published
5JT7	tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 1-(2-((2-morpholinoethyl)amino)-1H-benzo[d]imidazol-6-yl)guanidine 分子名称: GLYCEROL, N-(2-{[2-(morpholin-4-yl)ethyl]amino}-1H-benzimidazol-5-yl)guanidine, Queuine tRNA-ribosyltransferase, ... 著者 Ehrmann, F.R, Heine, A, Klebe, G. 登録日 2016-05-09 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Benzimidazole-based Inhibitors as a Novel Scaffold to Inhibit Z.mobilis TGT and Study Protein Flexibility and the Contributions of Active Site Residues to Binding Affinity of lin-Benzopurines. To be Published
5KAJ	Crystal structure of a dioxygenase in the Crotonase superfamily in P21, A319C mutant 分子名称: (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase, [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3~{R})-4-[[3-[2-[(~{E})-2-[3,5-bis(oxidanyl)phenyl]-1-oxidanyl-ethenyl]sulfanylethylamino]-3-oxidanylidene-propyl]amino]-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-butyl] hydrogen phosphate 著者 Li, K, Fielding, E.N, Condurso, H.L, Bruner, S.D. 登録日 2016-06-01 公開日 2017-06-21 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.681 Å) 主引用文献 Probing the structural basis of oxygen binding in a cofactor-independent dioxygenase. Acta Crystallogr D Struct Biol, 73, 2017
5K9R	PDE10a with imidazopyrazine inhibitor 分子名称: 4-[5-[1-(2-methoxyethyl)pyrazol-4-yl]-2-(quinolin-2-yloxymethyl)imidazo[1,2-a]pyrazin-8-yl]morpholine, MAGNESIUM ION, ZINC ION, ... 著者 Gibbs, A.G, Schubert, C. 登録日 2016-06-01 公開日 2016-08-24 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Discovery of novel potent imidazo[1,2-b]pyridazine PDE10a inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
5KBY	Crystal structure of dipeptidyl peptidase IV in complex with SYR-472 分子名称: 2-[[6-[(3~{R})-3-azanylpiperidin-1-yl]-3-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]methyl]-4-fluoranyl-benzenecarboni trile, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Skene, R.J, Jennings, A.J. 登録日 2016-06-03 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.24 Å) 主引用文献 Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism. Plos One, 11, 2016
5JRQ	BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor VEM-6-VEM 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, N-{2,4-difluoro-3-[5-(4-methoxyphenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]phenyl}propane-1-sulfonamide, ... 著者 Grasso, M.J, Marmorstein, R. 登録日 2016-05-06 公開日 2016-09-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.287 Å) 主引用文献 Chemically Linked Vemurafenib Inhibitors Promote an Inactive BRAF(V600E) Conformation. Acs Chem.Biol., 11, 2016
5JS3	Thermolysin in complex with JC114. 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, GLYCEROL, ... 著者 Krimmer, S.G, Cramer, J, Heine, A, Klebe, G. 登録日 2016-05-07 公開日 2016-12-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.16 Å) 主引用文献 Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound Ligands. J. Med. Chem., 59, 2016
5JT0	Crystal structure of glucosyl-3-phosphoglycerate synthase from Mycobacterium tuberculosis in complex with Mn2+, uridine-diphosphate (UDP) and glucosyl-3-phosphoglycerate (GPG) - GpgS*GPG*UDP*Mn2+ 分子名称: (2R)-2-(alpha-D-glucopyranosyloxy)-3-(phosphonooxy)propanoic acid, 1,2-ETHANEDIOL, Glucosyl-3-phosphoglycerate synthase, ... 著者 Albesa-Jove, D, Sancho-Vaello, E, Rodrigo-Unzueta, A, Comino, N, Carreras-Gonzalez, A, Arrasate, P, Urresti, S, Guerin, M.E. 登録日 2016-05-09 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS. Structure, 25, 2017
5JW9	The Crystal Structure of ELL2 Oclludin Domain and AFF4 peptide 分子名称: AF4/FMR2 family member 4, RNA polymerase II elongation factor ELL2 著者 Qi, S, Hurley, J.H. 登録日 2016-05-11 公開日 2017-02-08 実験手法 X-RAY DIFFRACTION (2.003 Å) 主引用文献 Structural basis for ELL2 and AFF4 activation of HIV-1 proviral transcription. Nat Commun, 8, 2017
5JT5	tRNA guanine Transglycosylase (TGT) in co-crystallized complex with 2-((2-morpholinoethyl)amino)-1H-benzo[d]imidazole-5-carboxamide 分子名称: 1,2-ETHANEDIOL, 2-{[2-(morpholin-4-yl)ethyl]amino}-1H-benzimidazole-6-carboxamide, CHLORIDE ION, ... 著者 Ehrmann, F.R, Heine, A, Klebe, G. 登録日 2016-05-09 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 Benzimidazole-based Inhibitors as a Novel Scaffold to Inhibit Z.mobilis TGT and Study Protein Flexibility and the Contributions of Active Site Residues to Binding Affinity of lin-Benzopurines. To be Published
5JXT	Crystal structure of MtISWI bound with histone H4 tail 分子名称: Chromatin-remodeling complex ATPase-like protein, Histone H4 著者 Chen, Z, Yan, L. 登録日 2016-05-13 公開日 2016-12-07 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (3.009 Å) 主引用文献 Structure and regulation of the chromatin remodeller ISWI Nature, 540, 2016
5JZA	Aspartyl/Asparaginyl beta-hydroxylase (AspH)oxygenase and TPR domains in complex with manganese and N-oxalylglycine 分子名称: Aspartyl/asparaginyl beta-hydroxylase, GLYCEROL, MANGANESE (II) ION, ... 著者 McDonough, M.A, Pfeffer, I. 登録日 2016-05-16 公開日 2017-05-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Aspartate/asparagine-beta-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nat Commun, 10, 2019
5JZU	Aspartyl/Asparaginyl beta-hydroxylase (AspH)oxygenase and TPR domains in complex with manganese, N-oxalylglycine and factor X substrate peptide fragment (26mer) 分子名称: Aspartyl/asparaginyl beta-hydroxylase, Coagulation factor X, MANGANESE (II) ION, ... 著者 McDonough, M.A, Pfeffer, I. 登録日 2016-05-17 公開日 2017-06-07 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Aspartate/asparagine-beta-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern. Nat Commun, 10, 2019
5K1S	crystal structure of AibC 分子名称: Oxidoreductase, zinc-binding dehydrogenase family, ZINC ION 著者 Bock, T, Mueller, R, Blankenfeldt, W. 登録日 2016-05-18 公開日 2016-08-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of AibC, a reductase involved in alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus. Acta Crystallogr.,Sect.F, 72, 2016
5JOU	Bacteroides ovatus Xyloglucan PUL GH31 分子名称: 1,2-ETHANEDIOL, Alpha-xylosidase BoGH31A, NICKEL (II) ION 著者 Thompson, A.J, Hemsworth, G.R, Stepper, J, Sobala, L.F, Coyle, T, Larsbrink, J, Spadiut, O, Stubbs, K.A, Brumer, H, Davies, G.J. 登録日 2016-05-03 公開日 2016-08-10 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural dissection of a complex Bacteroides ovatus gene locus conferring xyloglucan metabolism in the human gut. Open Biology, 6, 2016

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