5JS3

Thermolysin in complex with JC114.

Summary for 5JS3

Entry DOI	10.2210/pdb5js3/pdb
Descriptor	Thermolysin, ZINC ION, CALCIUM ION, ... (7 entities in total)
Functional Keywords	hydrolase, metalloprotease, hydrolase inhibitor complex
Biological source	Bacillus thermoproteolyticus
Cellular location	Secreted: P00800
Total number of polymer chains	1
Total formula weight	35460.17
Authors	Krimmer, S.G.,Cramer, J.,Heine, A.,Klebe, G. (deposition date: 2016-05-07, release date: 2016-12-21, Last modification date: 2024-01-10)
Primary citation	Krimmer, S.G.,Cramer, J.,Betz, M.,Fridh, V.,Karlsson, R.,Heine, A.,Klebe, G. Rational Design of Thermodynamic and Kinetic Binding Profiles by Optimizing Surface Water Networks Coating Protein-Bound Ligands. J. Med. Chem., 59:10530-10548, 2016 Cited by PubMed: 27933956 DOI: 10.1021/acs.jmedchem.6b00998 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.16 Å)

Structure validation