8E3F
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![BU of 8e3f by Molmil](/molmil-images/mine/8e3f) | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Wang, C. | 登録日 | 2022-08-17 | 公開日 | 2022-09-07 | 最終更新日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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8E5K
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![BU of 8e5k by Molmil](/molmil-images/mine/8e5k) | Escherichia coli Rho-dependent transcription pre-termination complex containing 21 nt long RNA spacer, Mg-ADP-BeF3, and NusG; TEC part | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Wang, C. | 登録日 | 2022-08-22 | 公開日 | 2022-09-07 | 最終更新日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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8E6X
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![BU of 8e6x by Molmil](/molmil-images/mine/8e6x) | Escherichia coli Rho-dependent transcription pre-termination complex containing 18 nt long RNA spacer, lambda-tR1 rut RNA, Mg-ADP-BeF3, and NusG; TEC part | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Molodtsov, V, Wang, C. | 登録日 | 2022-08-23 | 公開日 | 2022-09-07 | 最終更新日 | 2023-02-22 | 実験手法 | ELECTRON MICROSCOPY (4.27 Å) | 主引用文献 | Structural basis of Rho-dependent transcription termination. Nature, 614, 2023
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7NWG
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![BU of 7nwg by Molmil](/molmil-images/mine/7nwg) | Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. | 分子名称: | 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... | 著者 | Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. | 登録日 | 2021-03-16 | 公開日 | 2021-07-07 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
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5N8X
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6H58
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![BU of 6h58 by Molmil](/molmil-images/mine/6h58) | Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1 - Full 100S Hibernating E. coli Ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S1, ... | 著者 | Beckert, B, Turk, M, Czech, A, Berninghausen, O, Beckmann, R, Ignatova, Z, Plitzko, J, Wilson, D.N. | 登録日 | 2018-07-24 | 公開日 | 2018-09-05 | 最終更新日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (7.9 Å) | 主引用文献 | Structure of a hibernating 100S ribosome reveals an inactive conformation of the ribosomal protein S1. Nat Microbiol, 3, 2018
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5N95
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8F1I
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![BU of 8f1i by Molmil](/molmil-images/mine/8f1i) | SigN RNA polymerase early-melted intermediate bound to mismatch fragment dhsU36mm1 (-12T) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1J
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![BU of 8f1j by Molmil](/molmil-images/mine/8f1j) | SigN RNA polymerase early-melted intermediate bound to mismatch DNA fragment dhsU36mm2 (-12A) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1K
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![BU of 8f1k by Molmil](/molmil-images/mine/8f1k) | SigN RNA polymerase early-melted intermediate bound to full duplex DNA fragment dhsU36 (-12T) | 分子名称: | DNA (36-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Mueller, A.U, Chen, J, Darst, S.A. | 登録日 | 2022-11-05 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | A general mechanism for transcription bubble nucleation in bacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
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8QOI
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![BU of 8qoi by Molmil](/molmil-images/mine/8qoi) | Structure of the human 80S ribosome at 1.9 A resolution - the molecular role of chemical modifications and ions in RNA | 分子名称: | 18S rRNA (1740-MER), 28S rRNA (3773-MER), 40S ribosomal protein S10, ... | 著者 | Holvec, S, Barchet, C, Frechin, L, Hazemann, I, von Loeffelholz, O, Klaholz, B.P. | 登録日 | 2023-09-29 | 公開日 | 2024-06-12 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (1.9 Å) | 主引用文献 | The structure of the human 80S ribosome at 1.9 angstrom resolution reveals the molecular role of chemical modifications and ions in RNA. Nat.Struct.Mol.Biol., 2024
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4ZP6
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4ZP7
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4K6M
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4WLS
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![BU of 4wls by Molmil](/molmil-images/mine/4wls) | Crystal structure of the metal-free (repressor) form of E. Coli CUER, a copper efflux regulator, bound to COPA promoter DNA | 分子名称: | COPA PROMOTER DNA NON-TEMPLATE STRAND, COPA PROMOTER DNA NON-TEMPLATE STRAND (ALTERNATE CONFORMATION), COPA PROMOTER DNA TEMPLATE STRAND, ... | 著者 | Philips, S.J, Canalizo-Hernandez, M, Mondragon, A, O'Halloran, T.V. | 登録日 | 2014-10-08 | 公開日 | 2015-09-02 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.105 Å) | 主引用文献 | Allosteric transcriptional regulation via changes in the overall topology of the core promoter. Science, 349, 2015
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4M5D
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6KLE
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![BU of 6kle by Molmil](/molmil-images/mine/6kle) | Monomeric structure of Machupo virus polymerase bound to vRNA promoter | 分子名称: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | 著者 | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | 登録日 | 2019-07-30 | 公開日 | 2020-03-18 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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8PFJ
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![BU of 8pfj by Molmil](/molmil-images/mine/8pfj) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (not fully complementary scaffold; alternative state of RfaH) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-16 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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8PEN
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![BU of 8pen by Molmil](/molmil-images/mine/8pen) | fully recruited RfaH bound to E. coli transcription complex paused at ops site (alternative state of RfaH) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Zuber, P.K, Said, N, Hilal, T, Loll, B, Wahl, M.C, Knauer, S.H. | 登録日 | 2023-06-14 | 公開日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Concerted transformation of a hyper-paused transcription complex and its reinforcing protein. Nat Commun, 15, 2024
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6KLH
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![BU of 6klh by Molmil](/molmil-images/mine/6klh) | Dimeric structure of Machupo virus polymerase bound to vRNA promoter | 分子名称: | MANGANESE (II) ION, RNA (5'-R(*GP*CP*CP*UP*AP*GP*GP*AP*UP*CP*CP*AP*CP*UP*GP*UP*GP*CP*G)-3'), RNA-directed RNA polymerase L, ... | 著者 | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | 登録日 | 2019-07-30 | 公開日 | 2020-03-18 | 最終更新日 | 2021-12-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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7KIF
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![BU of 7kif by Molmil](/molmil-images/mine/7kif) | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 transcription factor | 分子名称: | DNA (55-MER), DNA (63-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2020-10-23 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
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7KIM
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![BU of 7kim by Molmil](/molmil-images/mine/7kim) | Mycobacterium tuberculosis WT RNAP transcription closed promoter complex with WhiB7 transcription factor | 分子名称: | DNA (45-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2020-10-23 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
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7KIN
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![BU of 7kin by Molmil](/molmil-images/mine/7kin) | Mycobacterium tuberculosis WT RNAP transcription open promoter complex with WhiB7 promoter | 分子名称: | DNA (49-MER), DNA (54-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Lilic, M, Darst, S.A, Campbell, E.A. | 登録日 | 2020-10-23 | 公開日 | 2021-04-21 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | 主引用文献 | Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7. Mol.Cell, 81, 2021
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6KLC
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![BU of 6klc by Molmil](/molmil-images/mine/6klc) | Structure of apo Lassa virus polymerase | 分子名称: | MANGANESE (II) ION, RNA-directed RNA polymerase L | 著者 | Peng, R, Xu, X, Jing, J, Peng, Q, Gao, G.F, Shi, Y. | 登録日 | 2019-07-30 | 公開日 | 2020-03-18 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural insight into arenavirus replication machinery. Nature, 579, 2020
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4LT6
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![BU of 4lt6 by Molmil](/molmil-images/mine/4lt6) | Crystal Structure of human poly(A) polymerase gamma | 分子名称: | 3'-DEOXYADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Poly(A) polymerase gamma | 著者 | Yang, Q, Nausch, L, Martin, G, Keller, W, Doublie, S. | 登録日 | 2013-07-23 | 公開日 | 2013-10-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | 主引用文献 | Crystal structure of human poly(a) polymerase gamma reveals a conserved catalytic core for canonical poly(a) polymerases. J.Mol.Biol., 426, 2014
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