PDB: 98041 件ウェブページステータス検索Chemie searchBIRD

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1GLV	THREE-DIMENSIONAL STRUCTURE OF THE GLUTATHIONE SYNTHETASE FROM ESCHERICHIA COLI B AT 2.0 ANGSTROMS RESOLUTION 分子名称: GLUTATHIONE SYNTHASE 著者 Yamaguchi, H, Kato, H, Tanaka, T, Katsube, Y. 登録日 1993-03-12 公開日 1994-01-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Three-dimensional structure of the glutathione synthetase from Escherichia coli B at 2.0 A resolution. J.Mol.Biol., 229, 1993
1GAY	CRYSTAL STRUCTURE OF MUTANT HUMAN LYSOZYME SUBSTITUTED AT THE SURFACE POSITIONS 分子名称: MUTANT LYSOZYME, SODIUM ION 著者 Funahashi, J, Takano, K, Yamagata, Y, Yutani, K. 登録日 2000-06-26 公開日 2000-06-29 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Role of surface hydrophobic residues in the conformational stability of human lysozyme at three different positions. Biochemistry, 39, 2000
1ARW	CRYSTAL STRUCTURES OF CYANIDE-AND TRIIODIDE-BOUND FORMS OF ARTHROMYCES RAMOSUS PEROXIDASE AT DIFFERENT PH VALUES. PERTURBATIONS OF ACTIVE SITE RESIDUES AND THEIR IMPLICATION IN ENZYME CATALYSIS 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CYANIDE ION, ... 著者 Fukuyama, K, Kunishima, N, Amada, F. 登録日 1995-04-25 公開日 1996-01-29 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of cyanide- and triiodide-bound forms of Arthromyces ramosus peroxidase at different pH values. Perturbations of active site residues and their implication in enzyme catalysis. J.Biol.Chem., 270, 1995
1FYH	1:1 COMPLEX BETWEEN AN INTERFERON GAMMA SINGLE-CHAIN VARIANT AND ITS RECEPTOR 分子名称: CHLORIDE ION, Interferon gamma, Interferon gamma receptor 1 著者 Randal, M, Kossiakoff, A.A. 登録日 2000-09-29 公開日 2000-10-11 最終更新日 2017-06-21 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex. Structure, 9, 2001
1B1X	STRUCTURE OF DIFERRIC MARE LACTOFERRIN AT 2.62A RESOLUTION 分子名称: CARBONATE ION, FE (III) ION, LACTOFERRIN 著者 Sharma, A.K, Srinivasan, A, Singh, T.P. 登録日 1998-11-24 公開日 1999-06-24 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Three-dimensional structure of mare diferric lactoferrin at 2.6 A resolution. J.Mol.Biol., 289, 1999
1GGT	THREE-DIMENSIONAL STRUCTURE OF A TRANSGLUTAMINASE: HUMAN BLOOD COAGULATION FACTOR XIII 分子名称: COAGULATION FACTOR XIII 著者 Yee, V.C, Pedersen, L.C, Trong, I.L, Bishop, P.D, Stenkamp, R.E, Teller, D.C. 登録日 1994-01-25 公開日 1995-07-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Three-dimensional structure of a transglutaminase: human blood coagulation factor XIII. Proc.Natl.Acad.Sci.USA, 91, 1994
2EB2	Crystal structure of mutated EGFR kinase domain (G719S) 分子名称: Epidermal growth factor receptor 著者 Yoshikawa, S, Kukimoto-Niino, M, Chen, L, Liu, Z.J, Wang, B.C, Shirouzu, M, Senba, K, Yamamoto, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2007-02-06 公開日 2008-02-12 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for the altered drug sensitivities of non-small cell lung cancer-associated mutants of human epidermal growth factor receptor Oncogene, 2012
1ATH	THE INTACT AND CLEAVED HUMAN ANTITHROMBIN III COMPLEX AS A MODEL FOR SERPIN-PROTEINASE INTERACTIONS 分子名称: ANTITHROMBIN III 著者 Schreuder, H.A, Hol, W.G.J. 登録日 1993-12-14 公開日 1995-02-07 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions. Nat.Struct.Biol., 1, 1994
1GG1	CRYSTAL STRUCTURE ANALYSIS OF DAHP SYNTHASE IN COMPLEX WITH MN2+ AND 2-PHOSPHOGLYCOLATE 分子名称: 2-PHOSPHOGLYCOLIC ACID, 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE, MANGANESE (II) ION, ... 著者 Wagner, T, Shumilin, I.A, Bauerle, R, Kretsinger, R.H. 登録日 2000-08-04 公開日 2000-10-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli: comparison of the Mn(2+)*2-phosphoglycolate and the Pb(2+)*2-phosphoenolpyruvate complexes and implications for catalysis. J.Mol.Biol., 301, 2000
1AVU	TRYPSIN INHIBITOR FROM SOYBEAN (STI) 分子名称: TRYPSIN INHIBITOR 著者 Song, H.K, Suh, S.W. 登録日 1997-09-20 公開日 1998-10-28 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina caffra and tissue-type plasminogen activator. J.Mol.Biol., 275, 1998
1AOT	NMR STRUCTURE OF THE FYN SH2 DOMAIN COMPLEXED WITH A PHOSPHOTYROSYL PEPTIDE, MINIMIZED AVERAGE STRUCTURE 分子名称: FYN PROTEIN-TYROSINE KINASE, PHOSPHOTYROSYL PEPTIDE 著者 Mulhern, T.D, Shaw, G.L, Morton, C.J, Day, A.J, Campbell, I.D. 登録日 1997-07-10 公開日 1998-01-14 最終更新日 2021-11-03 実験手法 SOLUTION NMR 主引用文献 The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity. Structure, 5, 1997
1AX4	TRYPTOPHANASE FROM PROTEUS VULGARIS 分子名称: POTASSIUM ION, TRYPTOPHANASE 著者 Isupov, M.N, Antson, A.A, Dodson, E.J, Dodson, G.G, Dementieva, I.S, Zakomirdina, L.N, Wilson, K.S, Dauter, Z, Lebedev, A.A, Harutyunyan, E.H. 登録日 1997-10-28 公開日 1998-01-28 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of tryptophanase. J.Mol.Biol., 276, 1998
5KH5	Crystal Structure of Steptococcus pneumoniae Undecaprenyl pyrophosphate Synthase (UPPS) IN COMPLEX WITH ~{N}-(3-azanyl-3-oxidanylidene-propyl)-5-(1-benzothiophen-5-yl)-1-(phenylmethyl)-~{N}-[(4-propan-2-yloxyphenyl)methyl]pyrazole-4-carboxamide 分子名称: Isoprenyl transferase, ~{N}-(3-azanyl-3-oxidanylidene-propyl)-5-(1-benzothiophen-5-yl)-1-(phenylmethyl)-~{N}-[(4-propan-2-yloxyphenyl)methyl]pyrazole-4-carboxamide 著者 Concha, N.O. 登録日 2016-06-14 公開日 2016-07-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Discovery and Characterization of a Class of Pyrazole Inhibitors of Bacterial Undecaprenyl Pyrophosphate Synthase. J.Med.Chem., 59, 2016
1APB	A PRO TO GLY MUTATION IN THE HINGE OF THE ARABINOSE-BINDING PROTEIN ENHANCES BINDING AND ALTERS SPECIFICITY: SUGAR-BINDING AND CRYSTALLOGRAPHIC STUDIES 分子名称: L-ARABINOSE-BINDING PROTEIN, alpha-D-fucopyranose, beta-D-fucopyranose 著者 Vermersch, P.S, Tesmer, J.J.G, Quiocho, F.A. 登録日 1991-11-15 公開日 1992-01-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 A Pro to Gly mutation in the hinge of the arabinose-binding protein enhances binding and alters specificity. Sugar-binding and crystallographic studies. J.Biol.Chem., 265, 1990
8SJ0	Structure of ternary complex of cGAS with dsDNA and bound 2'-dATP 分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MAGNESIUM ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-17 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
7QFT	Crystal structure of KLK6 in complex with compound 16a 分子名称: KLK6 Activity-Based Probe (Ahx-DPhe-Cha-Dht-Arg-DPP), Kallikrein-6 著者 Jagtap, P.K.A, Zhang, L, De Vita, E, Tate, E.W, Hennig, J. 登録日 2021-12-06 公開日 2022-11-09 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion. J.Am.Chem.Soc., 144, 2022
5JR7	Crystal structure of an ACRDYS heterodimer [RIa(92-365):C] of PKA 分子名称: ADENOSINE-5'-DIPHOSPHATE, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type I-alpha regulatory subunit 著者 Bruystens, J.G.H, Wu, J, Taylor, S.S. 登録日 2016-05-05 公開日 2017-03-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.56 Å) 主引用文献 Structure of a PKA RI alpha Recurrent Acrodysostosis Mutant Explains Defective cAMP-Dependent Activation. J. Mol. Biol., 428, 2016
3FTS	Leukotriene A4 hydrolase in complex with resveratrol 分子名称: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ... 著者 Davies, D.R. 登録日 2009-01-13 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
1B1U	CRYSTAL STRUCTURE OF THE BIFUNCTIONAL INHIBITOR RAGI 分子名称: PROTEIN (ALPHA-AMYLASE/TRYPSIN INHIBITOR RATI) 著者 Gourinath, S, Srinivasan, A, Singh, T.P. 登録日 1998-11-23 公開日 1998-12-02 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of the bifunctional inhibitor of trypsin and alpha-amylase from ragi seeds at 2.2 A resolution. Acta Crystallogr.,Sect.D, 56, 2000
1B10	SOLUTION NMR STRUCTURE OF RECOMBINANT SYRIAN HAMSTER PRION PROTEIN RPRP(90-231) , 25 STRUCTURES 分子名称: PROTEIN (PRION PROTEIN) 著者 James, T.L, Liu, H, Ulyanov, N.B, Farr-Jones, S. 登録日 1998-11-25 公開日 1998-12-02 最終更新日 2023-12-27 実験手法 SOLUTION NMR 主引用文献 Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform. Proc.Natl.Acad.Sci.USA, 94, 1997
3FTW	Leukotriene A4 hydrolase in complex with fragments N-(pyridin-3-ylmethyl)aniline and acetate 分子名称: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ... 著者 Davies, D.R. 登録日 2009-01-13 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
3FUD	Leukotriene A4 hydrolase in complex with N-methyl-1-(2-thiophen-2-ylphenyl)methanamine 分子名称: ACETATE ION, IMIDAZOLE, Leukotriene A-4 hydrolase, ... 著者 Davies, D.R. 登録日 2009-01-14 公開日 2009-07-28 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Discovery of leukotriene A4 hydrolase inhibitors using metabolomics biased fragment crystallography. J.Med.Chem., 52, 2009
8SI0	Structure of binary complex of human cGAS and bound cGAMP 分子名称: Cyclic GMP-AMP synthase, ZINC ION, cGAMP 著者 Wu, S, Sohn, J. 登録日 2023-04-14 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
1B65	Structure of l-aminopeptidase d-ala-esterase/amidase from ochrobactrum anthropi, a prototype for the serine aminopeptidases, reveals a new variant among the ntn hydrolase fold 分子名称: PROTEIN (AMINOPEPTIDASE) 著者 Bompard-Gilles, C, Villeret, V, Davies, G.J, Fanuel, L, Joris, B, Frere, J.M, Van Beeumen, J. 登録日 1999-01-20 公開日 1999-07-23 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi. Structure Fold.Des., 8, 2000
8BDN	VCB in complex with compound 23 分子名称: (2~{R})-3-methyl-1-[(2~{S},4~{R})-2-[(5~{R})-5-methyl-5-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-4~{H}-1,2,4-oxadiazol-3-yl]-4-oxidanyl-pyrrolidin-1-yl]-2-(3-methyl-1,2-oxazol-5-yl)butan-1-one, Elongin-B, Elongin-C, ... 著者 Sorrell, F.J, Mueller, J.E, Lehmann, M, Wegener, A. 登録日 2022-10-19 公開日 2023-02-15 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Systematic Potency and Property Assessment of VHL Ligands and Implications on PROTAC Design. Chemmedchem, 18, 2023

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