PDB: 46200 件ウェブページステータス検索Chemie searchBIRD

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4V99	The Crystallographic Structure of Panicum Mosaic Virus 分子名称: 5'-R(P*UP*UP*AP*AP*UP*AP*UP*UP*UP*UP*UP*AP*UP*UP*UP*UP*U)-3', CALCIUM ION, Capsid protein 著者 Makino, D.L, Larson, S.B, McPherson, A. 登録日 2012-07-04 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystallographic structure of Panicum Mosaic Virus (PMV). J.Struct.Biol., 181, 2013
4V8H	Crystal structure of HPF bound to the 70S ribosome. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Blaha, G.M, Steitz, T.A. 登録日 2011-12-11 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 How Hibernation Factors RMF, HPF, and YfiA Turn Off Protein Synthesis. Science, 336, 2012
4V9F	The re-refined crystal structure of the Haloarcula marismortui large ribosomal subunit at 2.4 Angstrom resolution: more complete structure of the L7/L12 and L1 stalk, L5 and LX proteins 分子名称: 23S Ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ... 著者 Gabdulkhakov, A. 登録日 2012-11-02 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.404 Å) 主引用文献 Revisiting the Haloarcula marismortui 50S ribosomal subunit model. Acta Crystallogr.,Sect.D, 69, 2013
4UXL	Structure of Human ROS1 Kinase Domain in Complex with PF-06463922 分子名称: (10R)-7-amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]benzoxadiazacyclotetradecine-3-carbonitrile, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS 著者 McTigue, M, Deng, Y, Liu, W, Brooun, A, Stewart, A. 登録日 2014-08-25 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Pf-06463922 is a Potent and Selective Next-Generation Ros1/Alk Inhibitor Capable of Blocking Crizotinib-Resistant Ros1 Mutations. Proc.Natl.Acad.Sci.USA, 112, 2015
4V67	Crystal structure of a translation termination complex formed with release factor RF2. 分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... 著者 Korostelev, A, Asahara, H, Lancaster, L, Laurberg, M, Hirschi, A, Noller, H.F. 登録日 2008-10-27 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of a translation termination complex formed with release factor RF2. Proc.Natl.Acad.Sci.USA, 105, 2008
4V8D	Structure analysis of ribosomal decoding (cognate tRNA-tyr complex). 分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... 著者 Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2011-12-07 公開日 2014-07-09 最終更新日 2019-07-03 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
4V95	Crystal structure of YAEJ bound to the 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Gagnon, M.G, Seetharaman, S.V, Bulkley, D.P, Steitz, T.A. 登録日 2012-01-27 公開日 2014-07-09 最終更新日 2018-07-11 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural basis for the rescue of stalled ribosomes: structure of YaeJ bound to the ribosome. Science, 335, 2012
4V9S	Crystal structure of antibiotic GE82832 bound to 70S ribosome 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. 登録日 2013-12-05 公開日 2014-07-09 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
6UFP	Structure of proline utilization A with the FAD covalently modified by L-thiazolidine-2-carboxylate and three cysteines (Cys46, Cys470, Cys638) modified to S,S-(2-HYDROXYETHYL)THIOCYSTEINE 分子名称: (2S)-1,3-thiazolidine-2-carboxylic acid, Bifunctional protein PutA, DI(HYDROXYETHYL)ETHER, ... 著者 Campbell, A.C, Tanner, J.J. 登録日 2019-09-24 公開日 2020-03-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.737 Å) 主引用文献 Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. Acs Chem.Biol., 15, 2020
4V51	Structure of the Thermus thermophilus 70S ribosome complexed with mRNA, tRNA and paromomycin 分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Selmer, M, Dunham, C.M, Murphy, F.V, Weixlbaumer, A, Petry, S, Weir, J.R, Kelley, A.C, Ramakrishnan, V. 登録日 2006-07-31 公開日 2014-07-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of the 70S ribosome complexed with mRNA and tRNA. Science, 313, 2006
7PK5	Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein) 分子名称: Cyclic di-GMP phosphodiesterase PdeL 著者 Fadel, J, Schirmer, T. 登録日 2021-08-25 公開日 2022-09-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Phosphodiesterase PdeL (EAL domain of crystals comprising full-length protein) To Be Published
7QWR	Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. 登録日 2022-01-25 公開日 2022-03-09 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
7QWQ	Ternary complex of ribosome nascent chain with SRP and NAC 分子名称: 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Jomaa, A, Gamerdinger, M, Hsieh, H, Wallisch, A, Chandrasekaran, V, Ulusoy, Z, Scaiola, A, Hegde, R, Shan, S, Ban, N, Deuerling, E. 登録日 2022-01-25 公開日 2022-03-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Science, 375, 2022
7QA0	Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound 1456 分子名称: Multiple virulence factor regulator MvfR, ~{N}-[[2-(3-chloranyl-4-propan-2-yloxy-phenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine 著者 Schmelz, S, Blankenfeldt, W. 登録日 2021-11-15 公開日 2022-11-23 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity Ssrn, 2024
7QA3	Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-phenoxyphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine 分子名称: Multiple virulence factor regulator MvfR, N-[[2-(4-phenoxyphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine 著者 Schmelz, S, Blankenfeldt, W. 登録日 2021-11-15 公開日 2022-11-23 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity Ssrn, 2024
7QAV	Crystal structure of PqsR (MvfR) ligand-binding domain in complex with compound N-((2-(4-cyclopropylphenyl)thiazol-5-yl)methyl)-2-(trifluoromethyl)pyridin-4-amine 分子名称: Multiple virulence factor regulator MvfR, ~{N}-[[2-(4-cyclopropylphenyl)-1,3-thiazol-5-yl]methyl]-2-(trifluoromethyl)pyridin-4-amine 著者 Schmelz, S, Blankenfeldt, W. 登録日 2021-11-17 公開日 2022-11-30 最終更新日 2024-06-12 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Discovery and Optimization of Thiazole-Based Quorum Sensing Inhibitors as Potent Blockers of Pseudomonas Aeruginosa Pathogenicity Ssrn, 2024
4UG0	STRUCTURE OF THE HUMAN 80S RIBOSOME 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... 著者 Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. 登録日 2015-03-20 公開日 2015-06-10 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the human 80S ribosome NATURE, 520, 2015
7PB4	Cenp-HIK 3-protein complex 分子名称: Centromere protein H, Centromere protein I, Centromere protein K 著者 Bellini, D, Yatskevich, S, Muir, W.K, Barford, D. 登録日 2021-07-30 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome. Science, 376, 2022
6KO7	Crystal structure of the Ethidium bound RamR determined with XtaLAB Synergy 分子名称: ETHIDIUM, Putative regulatory protein, SULFATE ION 著者 Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. 登録日 2019-08-08 公開日 2019-10-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Development of a structure determination method using a multidrug-resistance regulator protein as a framework. Biochem.Biophys.Res.Commun., 518, 2019
5M25	Modulation of MLL1 Methyltransferase Activity 分子名称: (2~{S})-2-[[(2~{S})-2-[[(2~{S})-2-azanyl-3-oxidanyl-propanoyl]amino]propanoyl]amino]-5-carbamimidamido-~{N}-[(2~{S})-1-[[4-[(~{E})-[4-(hydroxymethyl)phenyl]diazenyl]phenyl]methylamino]-1-oxidanylidene-propan-2-yl]pentanamide, WD repeat-containing protein 5 著者 Srinivasan, V. 登録日 2016-10-11 公開日 2017-06-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Controlled inhibition of methyltransferases using photoswitchable peptidomimetics: towards an epigenetic regulation of leukemia. Chem Sci, 8, 2017
3L3M	PARP complexed with A927929 分子名称: 2-{2-fluoro-4-[(2S)-piperidin-2-yl]phenyl}-1H-benzimidazole-7-carboxamide, Poly [ADP-ribose] polymerase 1 著者 Park, C.H. 登録日 2009-12-17 公開日 2010-06-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Optimization of phenyl-substituted benzimidazole carboxamide poly(ADP-ribose) polymerase inhibitors: identification of (S)-2-(2-fluoro-4-(pyrrolidin-2-yl)phenyl)-1H-benzimidazole-4-carboxamide (A-966492), a highly potent and efficacious inhibitor. J.Med.Chem., 53, 2010
6KO9	Crystal structure of the Gefitinib Intermediate 1 bound RamR determined with XtaLAB Synergy 分子名称: 4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-methoxy-quinazolin-6-ol, Putative regulatory protein, SULFATE ION 著者 Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. 登録日 2019-08-08 公開日 2019-10-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Development of a structure determination method using a multidrug-resistance regulator protein as a framework. Biochem.Biophys.Res.Commun., 518, 2019
2QPY	AR LBD with small molecule 分子名称: 5-ALPHA-DIHYDROTESTOSTERONE, Androgen receptor, Coactivator peptide, ... 著者 Estebanez-Perpina, E, Fletterick, R. 登録日 2007-07-25 公開日 2007-09-25 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A surface on the androgen receptor that allosterically regulates coactivator binding. Proc.Natl.Acad.Sci.Usa, 104, 2007
6KO8	Crystal structure of the Cholic acid bound RamR determined with XtaLAB Synergy 分子名称: CHOLIC ACID, Putative regulatory protein, SULFATE ION 著者 Matsumoto, T, Nakashima, R, Yamano, A, Nishino, K. 登録日 2019-08-08 公開日 2019-10-09 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Development of a structure determination method using a multidrug-resistance regulator protein as a framework. Biochem.Biophys.Res.Commun., 518, 2019
3L3L	PARP complexed with A906894 分子名称: 3-oxo-2-piperidin-4-yl-2,3-dihydro-1H-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1 著者 Park, C.H. 登録日 2009-12-17 公開日 2010-12-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery and SAR of substituted 3-oxoisoindoline-4-carboxamides as potent inhibitors of poly(ADP-ribose) polymerase (PARP) for the treatment of cancer. Bioorg.Med.Chem.Lett., 20, 2010

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