6UFP
Structure of proline utilization A with the FAD covalently modified by L-thiazolidine-2-carboxylate and three cysteines (Cys46, Cys470, Cys638) modified to S,S-(2-HYDROXYETHYL)THIOCYSTEINE
Summary for 6UFP
Entry DOI | 10.2210/pdb6ufp/pdb |
Descriptor | Bifunctional protein PutA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, (2S)-1,3-thiazolidine-2-carboxylic acid, ... (9 entities in total) |
Functional Keywords | flavoenzyme, rossmann fold, proline catabolism, substrate channeling, bifunctional enzyme, oxidoreductase |
Biological source | Sinorhizobium meliloti (strain SM11) More |
Total number of polymer chains | 2 |
Total formula weight | 268352.88 |
Authors | Campbell, A.C.,Tanner, J.J. (deposition date: 2019-09-24, release date: 2020-03-18, Last modification date: 2023-10-11) |
Primary citation | Campbell, A.C.,Becker, D.F.,Gates, K.S.,Tanner, J.J. Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate. Acs Chem.Biol., 15:936-944, 2020 Cited by PubMed: 32159324DOI: 10.1021/acschembio.9b00935 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.737 Å) |
Structure validation
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