1Z6O
 
 | | Crystal Structure of Trichoplusia ni secreted ferritin | | 分子名称: | CALCIUM ION, FE (III) ION, Ferritin heavy chain, ... | | 著者 | Hamburger, A.E, West Jr, A.P, Hamburger, Z.A, Hamburger, P, Bjorkman, P.J. | | 登録日 | 2005-03-22 | | 公開日 | 2005-05-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Crystal structure of a secreted insect ferritin reveals a symmetrical arrangement of heavy and light chains.
J.Mol.Biol., 349, 2005
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2NXD
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2E6Y
 | | Covalent complex of orotidine 5'-monophosphate decarboxylase (ODCase) with 6-Iodo-UMP | | 分子名称: | GLYCEROL, Orotidine 5'-phosphate decarboxylase, URIDINE-5'-MONOPHOSPHATE | | 著者 | Fujihashi, M, Bello, A.M, Kotra, L.P, Pai, E.F. | | 登録日 | 2007-01-05 | | 公開日 | 2007-02-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A Potent, Covalent Inhibitor of Orotidine 5'-Monophosphate Decarboxylase with Antimalarial Activity.
J.Med.Chem., 50, 2007
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5TQQ
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5ETA
 | | Structure of MAPK14 with bound the KIM domain of the Toxoplasma protein GRA24 | | 分子名称: | Mitogen-activated protein kinase 14, Putative transmembrane protein | | 著者 | Pellegrini, E, Palencia, A, Braun, L, Kapp, U, Bougdour, A, Belrhali, H, Bowler, M.W, Hakimi, M. | | 登録日 | 2015-11-17 | | 公開日 | 2016-10-26 | | 最終更新日 | 2019-02-20 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis for the Subversion of MAP Kinase Signaling by an Intrinsically Disordered Parasite Secreted Agonist.
Structure, 25, 2017
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5LRT
 | | Structure of the Deamidase-Depupylase Dop of the Prokaryotic Ubiquitin-like Modification Pathway in Complex with ADP and Phosphate | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, DI(HYDROXYETHYL)ETHER, Depupylase, ... | | 著者 | Bolten, M, Vahlensieck, C, Lipp, C, Leibundgut, M, Ban, N, Weber-Ban, E. | | 登録日 | 2016-08-19 | | 公開日 | 2017-02-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Depupylase Dop Requires Inorganic Phosphate in the Active Site for Catalysis.
J. Biol. Chem., 292, 2017
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5LSH
 | | human lysozyme in complex with a tetrasaccharide fragment of the O-chain of LPS from Klebsiella pneumoniae | | 分子名称: | CHLORIDE ION, Lysozyme C, SODIUM ION, ... | | 著者 | Zhang, R, Nifantiev, N.E, Krylov, V, Luetteke, T, Scheidig, A.J, Siebert, H.-C. | | 登録日 | 2016-08-26 | | 公開日 | 2017-06-21 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.061 Å) | | 主引用文献 | Lysozyme's lectin-like characteristics facilitates its immune defense function.
Q. Rev. Biophys., 50, 2017
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5LSW
 | | A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell differentiation protein RCD1 homolog, LD12033p, ... | | 著者 | Sgromo, A, Raisch, T, Bawankar, P, Bhandari, D, Chen, Y, Kuzuoglu-Ozturk, D, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-09-05 | | 公開日 | 2017-02-15 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | A CAF40-binding motif facilitates recruitment of the CCR4-NOT complex to mRNAs targeted by Drosophila Roquin.
Nat Commun, 8, 2017
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4HBV
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand | | 分子名称: | 1,2-ETHANEDIOL, 6-bromo-3-methyl-3,4-dihydroquinazolin-2(1H)-one, Bromodomain-containing protein 4 | | 著者 | Filippakopoulos, P, Picaud, S, Qi, J, Felletar, I, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A, Fish, P.V, Bunnage, M.E, Cook, A.S, Owen, D.R, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2012-09-28 | | 公開日 | 2012-10-31 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit.
J.Med.Chem., 55, 2012
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4A0X
 | | Structure of the global transcription regulator FapR from Staphylococcus aureus | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, TRANSCRIPTION FACTOR FAPR, ... | | 著者 | Albanesi, D, Guerin, M.E, Buschiazzo, A, de Mendoza, D, Alzari, P.M. | | 登録日 | 2011-09-13 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus Aureus.
Plos Pathog., 9, 2013
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5M7K
 | | Blastochloris viridis photosynthetic reaction center - RC_vir_xfel | | 分子名称: | (2E,6E,10E,14E,18E,22E,26E)-3,7,11,15,19,23,27,31-OCTAMETHYLDOTRIACONTA-2,6,10,14,18,22,26,30-OCTAENYL TRIHYDROGEN DIPHOSPHATE, 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL A, ... | | 著者 | Sharma, A.S, Johansson, L, Dunevall, E, Wahlgren, W.Y, Neutze, R, Katona, G. | | 登録日 | 2016-10-28 | | 公開日 | 2017-02-08 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Asymmetry in serial femtosecond crystallography data.
Acta Crystallogr A Found Adv, 73, 2017
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5M80
 | | Translation initiation factor 4E in complex with (RP)-iPr-m7GppSpG mRNA 5' cap analog | | 分子名称: | Eukaryotic translation initiation factor 4E, GLYCEROL, [[[(3~{a}~{R},4~{R},6~{R},6~{a}~{R})-4-(2-azanyl-7-methyl-6-oxidanylidene-1~{H}-purin-7-ium-9-yl)-2,2-dimethyl-3~{a},4,6,6~{a}-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-oxidanylidene-3~{H}-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Warminski, M, Nowak, E, Kowalska, J, Jemielity, J, Nowotny, M. | | 登録日 | 2016-10-28 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Translation initiation factor 4E in complex with (RP)-iPr-m7GppSpG mRNA 5' cap analog
To Be Published
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5MYD
 | | Convergent evolution involving dimeric and trimeric dUTPases in signalling. | | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DUTPase, MAGNESIUM ION | | 著者 | Donderis, J, Bowring, J, Maiques, E, Ciges-Tomas, J.R, Alite, C, Mehmedov, I, Tormo-Mas, M.A, Penades, J.R, Marina, A. | | 登録日 | 2017-01-26 | | 公開日 | 2017-09-06 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Convergent evolution involving dimeric and trimeric dUTPases in pathogenicity island mobilization.
PLoS Pathog., 13, 2017
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3JAD
 | | Structure of alpha-1 glycine receptor by single particle electron cryo-microscopy, strychnine-bound state | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alphaZ1, STRYCHNINE | | 著者 | Du, J, Lu, W, Wu, S.P, Cheng, Y.F, Gouaux, E. | | 登録日 | 2015-06-08 | | 公開日 | 2015-09-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Glycine receptor mechanism elucidated by electron cryo-microscopy.
Nature, 526, 2015
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4K85
 | | Crystal structure of human ceramide-1-phosphate transfer protein (CPTP) in complex with 12:0 Ceramide-1-Phosphate (12:0-C1P) | | 分子名称: | (2S,3R,4E)-2-(dodecanoylamino)-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, Glycolipid transfer protein domain-containing protein 1 | | 著者 | Simanshu, D.K, Brown, R.E, Patel, D.J. | | 登録日 | 2013-04-17 | | 公開日 | 2013-07-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | | 主引用文献 | Non-vesicular trafficking by a ceramide-1-phosphate transfer protein regulates eicosanoids.
Nature, 500, 2013
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5M5Q
 | | COPS5(2-257) IN COMPLEX WITH A AZAINDOLE (COMPOUND 4) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-[(3~{R})-3-(1~{H}-benzimidazol-2-yl)morpholin-4-yl]-3-[2-(4-methyl-2-phenyl-phenyl)-1~{H}-pyrrolo[2,3-b]pyridin-3-yl]propan-1-one, COP9 signalosome complex subunit 5, ... | | 著者 | Renatus, M, Altmann, E. | | 登録日 | 2016-10-22 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5.
Angew. Chem. Int. Ed. Engl., 56, 2017
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1Z95
 | | Crystal Structure of the Androgen Receptor Ligand-binding Domain W741L Mutant Complex with R-bicalutamide | | 分子名称: | Androgen Receptor, R-BICALUTAMIDE, SULFATE ION | | 著者 | Bohl, C.E, Gao, W, Miller, D.D, Bell, C.E, Dalton, J.T. | | 登録日 | 2005-03-31 | | 公開日 | 2005-04-19 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for antagonism and resistance of bicalutamide in prostate cancer.
Proc.Natl.Acad.Sci.Usa, 102, 2005
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4AQ1
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6BJR
 | | Crystal structure of prothrombin mutant S101C/A470C | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, Prothrombin, ... | | 著者 | Chinnaraj, M, Chen, Z, Pelc, L, Grese, Z, Bystranowska, D, Di Cera, E, Pozzi, N. | | 登録日 | 2017-11-06 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (6 Å) | | 主引用文献 | Structure of prothrombin in the closed form reveals new details on the mechanism of activation.
Sci Rep, 8, 2018
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5M7H
 | | Crystal structure of Bacillus subtilis EngA in complex with phosphate ion and GMPPNP | | 分子名称: | GTPase Der, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | | 著者 | da Silveira Tome, C, Foucher, A.E, Jault, J.M, Housset, D. | | 登録日 | 2016-10-27 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | | 主引用文献 | Crystal structure of Bacillus subtilis EngA in complex with phosphate ion and GMPPNP
To Be Published
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2GFQ
 | | Structure of Protein of Unknown Function PH0006 from Pyrococcus horikoshii | | 分子名称: | MAGNESIUM ION, SULFATE ION, UPF0204 protein PH0006 | | 著者 | Cuff, M.E, Skarina, T, Gorodichtchenskaia, E, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2006-03-22 | | 公開日 | 2006-04-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structure of hypothetical protein ph0006 from Pyrococcus horikoshii
To be Published
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3CJW
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7G21
 | | Crystal Structure of human FABP4 in complex with 4-hydroxy-2-[(E)-2-(2-phenylcyclohexyl)ethenyl]-2,3-dihydropyran-6-one | | 分子名称: | (6R)-4-hydroxy-6-{(E)-2-[(1R,2S)-2-phenylcyclohexyl]ethenyl}-5,6-dihydro-2H-pyran-2-one, CHLORIDE ION, FORMIC ACID, ... | | 著者 | Ehler, A, Benz, J, Obst, U, Boehringer, M, Rudolph, M.G. | | 登録日 | 2023-05-04 | | 公開日 | 2023-06-14 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | | 主引用文献 | Crystal Structure of a human FABP4 complex
To be published
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3AKY
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3AID
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