4V88
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![BU of 4v88 by Molmil](/molmil-images/mine/4v88) | The structure of the eukaryotic ribosome at 3.0 A resolution. | 分子名称: | 18S RIBOSOMAL RNA, 18S rRNA, 25S rRNA, ... | 著者 | Ben-Shem, A, Garreau de Loubresse, N, Melnikov, S, Jenner, L, Yusupova, G, Yusupov, M. | 登録日 | 2011-10-11 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The structure of the eukaryotic ribosome at 3.0 angstrom resolution. Science, 334, 2011
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1JSU
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![BU of 1jsu by Molmil](/molmil-images/mine/1jsu) | P27(KIP1)/CYCLIN A/CDK2 COMPLEX | 分子名称: | CYCLIN A, CYCLIN-DEPENDENT KINASE-2, P27, ... | 著者 | Russo, A.A, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 1996-07-03 | 公開日 | 1997-07-29 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex. Nature, 382, 1996
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1JST
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![BU of 1jst by Molmil](/molmil-images/mine/1jst) | PHOSPHORYLATED CYCLIN-DEPENDENT KINASE-2 BOUND TO CYCLIN A | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CYCLIN A, CYCLIN-DEPENDENT KINASE-2, ... | 著者 | Russo, A.A, Jeffrey, P.D, Pavletich, N.P. | 登録日 | 1996-07-03 | 公開日 | 1997-01-11 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural basis of cyclin-dependent kinase activation by phosphorylation. Nat.Struct.Biol., 3, 1996
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1KE8
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![BU of 1ke8 by Molmil](/molmil-images/mine/1ke8) | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH 4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE | 分子名称: | 4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2 | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.M, Shewchuk, L.M, Kuyper, L.F. | 登録日 | 2001-11-14 | 公開日 | 2002-05-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
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1KE6
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![BU of 1ke6 by Molmil](/molmil-images/mine/1ke6) | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE | 分子名称: | Cell division protein kinase 2, N-METHYL-{4-[2-(7-OXO-6,7-DIHYDRO-8H-[1,3]THIAZOLO[5,4-E]INDOL-8-YLIDENE)HYDRAZINO]PHENYL}METHANESULFONAMIDE | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.H, Shewchuk, L.M, Kuyper, L.F. | 登録日 | 2001-11-14 | 公開日 | 2002-05-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
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1KE9
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![BU of 1ke9 by Molmil](/molmil-images/mine/1ke9) | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH 3-{[4-({[AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE | 分子名称: | 3-{[4-([AMINO(IMINO)METHYL]AMINOSULFONYL)ANILINO]METHYLENE}-2-OXO-2,3-DIHYDRO-1H-INDOLE, Cell division protein kinase 2 | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.M, Shewchuk, L.M, Kuyper, L.F. | 登録日 | 2001-11-14 | 公開日 | 2002-05-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
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1KE7
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![BU of 1ke7 by Molmil](/molmil-images/mine/1ke7) | CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH 3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE | 分子名称: | 3-{[(2,2-DIOXIDO-1,3-DIHYDRO-2-BENZOTHIEN-5-YL)AMINO]METHYLENE}-5-(1,3-OXAZOL-5-YL)-1,3-DIHYDRO-2H-INDOL-2-ONE, Cell division protein kinase 2 | 著者 | Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.H, Shewchuk, L.M, Kuyper, L.F. | 登録日 | 2001-11-14 | 公開日 | 2002-05-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis. J.Med.Chem., 44, 2001
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1Y0J
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![BU of 1y0j by Molmil](/molmil-images/mine/1y0j) | Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction | 分子名称: | Erythroid transcription factor, ZINC ION, Zinc-finger protein ush | 著者 | Liew, C.K, Simpson, R.J.Y, Kwan, A.H.Y, Crofts, L.A, Loughlin, F.E, Matthews, J.M, Crossley, M, Mackay, J.P. | 登録日 | 2004-11-15 | 公開日 | 2005-01-25 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/Friend of GATA interaction Proc.Natl.Acad.Sci.Usa, 102, 2005
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9FMD
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8INK
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![BU of 8ink by Molmil](/molmil-images/mine/8ink) | |
8IE3
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![BU of 8ie3 by Molmil](/molmil-images/mine/8ie3) | |
8IDY
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![BU of 8idy by Molmil](/molmil-images/mine/8idy) | |
8IPD
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![BU of 8ipd by Molmil](/molmil-images/mine/8ipd) | |
8IDT
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![BU of 8idt by Molmil](/molmil-images/mine/8idt) | |
4V9P
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4V24
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![BU of 4v24 by Molmil](/molmil-images/mine/4v24) | Sphingosine kinase 1 in complex with PF-543 | 分子名称: | ACETATE ION, SPHINGOSINE KINASE 1, {(2R)-1-[4-({3-METHYL-5-[(PHENYLSULFONYL)METHYL]PHENOXY}METHYL)BENZYL]PYRROLIDIN-2-YL}METHANOL | 著者 | Elkins, J.M, Wang, J, Sorrell, F, Tallant, C, Wang, D, Shrestha, L, Bountra, C, von Delft, F, Knapp, S, Edwards, A. | 登録日 | 2014-10-05 | 公開日 | 2014-10-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of Sphingosine Kinase 1 with Pf-543. Acs Med.Chem.Lett., 5, 2014
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3FIW
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![BU of 3fiw by Molmil](/molmil-images/mine/3fiw) | Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor | 分子名称: | DI(HYDROXYETHYL)ETHER, Putative tetR-family transcriptional regulator | 著者 | Singer, A.U, Xu, X, Chang, C, Gu, J, Edwards, A.M, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2008-12-12 | 公開日 | 2009-01-13 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of SCO0253, a Tetr-family transcriptional regulator from Streptomyces coelicolor To be Published
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1Y8R
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8IEX
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4V69
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![BU of 4v69 by Molmil](/molmil-images/mine/4v69) | Ternary complex-bound E.coli 70S ribosome. | 分子名称: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Villa, E, Sengupta, J, Trabuco, L.G, LeBarron, J, Baxter, W.T, Shaikh, T.R, Grassucci, R.A, Nissen, P, Ehrenberg, M, Schulten, K, Frank, J. | 登録日 | 2008-12-11 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | 主引用文献 | Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis Proc.Natl.Acad.Sci.USA, 106, 2009
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8C91
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![BU of 8c91 by Molmil](/molmil-images/mine/8c91) | Cryo-EM captures early ribosome assembly in action | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Lauer, S, Nikolay, R, Qin, B. | 登録日 | 2023-01-21 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (4.19 Å) | 主引用文献 | Cryo-EM captures early ribosome assembly in action. Nat Commun, 14, 2023
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4V47
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![BU of 4v47 by Molmil](/molmil-images/mine/4v47) | Real space refined coordinates of the 30S and 50S subunits fitted into the low resolution cryo-EM map of the EF-G.GTP state of E. coli 70S ribosome | 分子名称: | 16S RIBOSOMAL RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Gao, H, Sengupta, J, Valle, M, Korostelev, A, Eswar, N, Stagg, S.M, Van Roey, P, Agrawal, R.K, Harvey, S.T, Sali, A, Chapman, M.S, Frank, J. | 登録日 | 2003-05-06 | 公開日 | 2014-07-09 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (12.3 Å) | 主引用文献 | Study of the structural dynamics of the E. coli 70S ribosome using real space refinement Cell(Cambridge,Mass.), 113, 2003
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8C8X
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![BU of 8c8x by Molmil](/molmil-images/mine/8c8x) | Cryo-EM captures early ribosome assembly in action | 分子名称: | 23S rRNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | 著者 | Lauer, S, Nikolay, R, Qin, B. | 登録日 | 2023-01-21 | 公開日 | 2023-04-05 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (3.93 Å) | 主引用文献 | Cryo-EM captures early ribosome assembly in action. Nat Commun, 14, 2023
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4V7S
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![BU of 4v7s by Molmil](/molmil-images/mine/4v7s) | Crystal structure of the E. coli ribosome bound to telithromycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | 登録日 | 2010-08-05 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.2547 Å) | 主引用文献 | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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9EMA
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![BU of 9ema by Molmil](/molmil-images/mine/9ema) | RUVBL1/2 in complex with ATP and CB-6644 inhibitor | 分子名称: | 5-chloranyl-2-ethoxy-4-fluoranyl-~{N}-[4-[[3-(methoxymethyl)-1-oxidanylidene-6,7-dihydro-5~{H}-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxidanylidene-butyl]benzamide, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Lopez-Perrote, A, Llorca, O, Garcia-Martin, C. | 登録日 | 2024-03-07 | 公開日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Mechanism of allosteric inhibition of RUVBL1-RUVBL2 by the small-molecule CB-6644 Cell Rep Phys Sci, 2024
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