9EMA

RUVBL1/2 in complex with ATP and CB-6644 inhibitor

This is a non-PDB format compatible entry.

Summary for 9EMA

• Entry DOI: 10.2210/pdb9ema/pdb
• EMDB information: 19815
• Descriptor: RuvB-like 1, RuvB-like 2, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: ruvbl1, ruvbl2, cb-6644, inhibitor, chaperone
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 315739.50

Authors

Lopez-Perrote, A.,Llorca, O.,Garcia-Martin, C. (deposition date: 2024-03-07, release date: 2024-05-15, Last modification date: 2025-03-12)

• Primary citation: Garcia-Martin, C.,Lopez-Perrote, A.,Boskovic, J.,Llorca, O.; Mechanism of allosteric inhibition of RUVBL1-RUVBL2 by the small-molecule CB-6644; Cell Rep Phys Sci, 2024; DOI: 10.1016/j.xcrp.2024.101982

Experimental method

ELECTRON MICROSCOPY (2.4 Å)