PDB: 19040 件ウェブページステータス検索Chemie searchBIRD

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6SWT	Affimer9 co-crystalised with the CH domains of alpha actinin 2. 分子名称: Affimer 9, Alpha-actinin-2 著者 Peckham, M, Trinh, C.H, Rogers, B. 登録日 2019-09-23 公開日 2020-10-07 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Nanoscale Pattern Extraction from Relative Positions of Sparse 3D Localizations. Nano Lett., 21, 2021
6JM9	cryo-EM structure of DOT1L bound to unmodified nucleosome 分子名称: DNA strand I, DNA strand J, Histone H2A, ... 著者 Jang, S, Song, J.J. 登録日 2019-03-07 公開日 2019-05-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7.3 Å) 主引用文献 Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
6JKG	The NAD+-free form of human NSDHL 分子名称: Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 著者 Kim, D, Lee, S.J, Lee, B. 登録日 2019-02-28 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity. Cell.Mol.Life Sci., 78, 2021
6JHK	Crystal Structure of Bacillus subtilis RsbS 分子名称: RsbS negative regulator of sigma-B 著者 Kwon, E, Pathak, D, Dahal, P, Kim, D.Y. 登録日 2019-02-18 公開日 2019-09-11 最終更新日 2019-11-20 実験手法 X-RAY DIFFRACTION (3.101 Å) 主引用文献 Structural insights into stressosome assembly. Iucrj, 6, 2019
6JKH	The NAD+-bound form of human NSDHL 分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating 著者 Kim, D, Lee, S.J, Lee, B. 登録日 2019-02-28 公開日 2020-03-04 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of human NSDHL and development of its novel inhibitor with the potential to suppress EGFR activity. Cell.Mol.Life Sci., 78, 2021
6JMA	cryo-EM structure of DOT1L bound to H2B ubiquitinated nucleosome 分子名称: DNA I&J, Histone H2A, Histone H2B 1.1, ... 著者 Jang, S, Song, J.J. 登録日 2019-03-07 公開日 2019-05-15 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (6.8 Å) 主引用文献 Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase. Genes Dev., 33, 2019
7QS6	Solution structure of thanatin-like derivative 7 in complex with E.coli LptA 分子名称: Lipopolysaccharide export system protein LptA, Thanatin-like derivative 著者 Moehle, K, Zerbe, O. 登録日 2022-01-12 公開日 2023-05-10 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae. Sci Adv, 9, 2023
7RR0	SARS-CoV-2 receptor binding domain bound to Fab PDI 222 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PDI 222 Fab Heavy Chain, PDI 222 Fab Light Chain, ... 著者 Pymm, P, Glukhova, A, Black, K.A, Tham, W.H. 登録日 2021-08-08 公開日 2021-10-06 最終更新日 2021-10-27 実験手法 ELECTRON MICROSCOPY (3.12 Å) 主引用文献 Landscape of human antibody recognition of the SARS-CoV-2 receptor binding domain. Cell Rep, 37, 2021
6KEC	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 4-ethoxy-5,16-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one 分子名称: 4-ethoxy-5,16-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Lee, B.I, Park, T.H. 登録日 2019-07-04 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research. Molecules, 26, 2021
6KEH	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 6,16-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one 分子名称: 6,16-dimethoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Lee, B.I, Park, T.H. 登録日 2019-07-04 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.553 Å) 主引用文献 Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research. Molecules, 26, 2021
6KEJ	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 6-[2-(diethylamino)ethoxy]-16-methoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one 分子名称: 6-[2-(diethylamino)ethoxy]-16-methoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(17),3,5,7,9,13,15-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Lee, B.I, Park, T.H. 登録日 2019-07-04 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research. Molecules, 26, 2021
6K40	Crystal structure of alkyl hydroperoxide reductase from D. radiodurans R1 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Alkyl hydroperoxide reductase AhpD, DI(HYDROXYETHYL)ETHER, ... 著者 Kim, M.-K, Zhang, J, Zhao, L. 登録日 2019-05-22 公開日 2020-05-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of the AhpD-like protein DR1765 from Deinococcus radiodurans R1. Biochem.Biophys.Res.Commun., 529, 2020
6KEK	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 6-hydroxy-16-methoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(16),3,5,7,9,13(17),14-heptaen-12-one 分子名称: 6-hydroxy-16-methoxy-11-methyl-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(16),3,5,7,9,13(17),14-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Lee, B.I, Park, T.H. 登録日 2019-07-04 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.553 Å) 主引用文献 Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research. Molecules, 26, 2021
4YQV	Glutathione S-transferase Omega 1 bound to covalent inhibitor C4-10 分子名称: 2-(ethylsulfanyl)-N-methyl-N-[(1-phenyl-1H-pyrazol-4-yl)methyl]acetamide, Glutathione S-transferase omega-1 著者 Stuckey, J.A. 登録日 2015-03-13 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor. Nat Commun, 7, 2016
6KN5	Crystal structure of AFF4 C-terminal domain 分子名称: AF4/FMR2 family member 4 著者 Chen, L.J, Yang, W.S, Xu, R.M. 登録日 2019-08-03 公開日 2020-07-08 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Acetylation of histone H3K27 signals the transcriptional elongation for estrogen receptor alpha. Commun Biol, 3, 2020
7R6P	Solution structure of peptide toxin MIITX2-Mg1a from the venom of the Australian giant red bull ant Myrmecia gulosa 分子名称: U-myrmeciitoxin(02)-Mg1a 著者 Chin, Y.K, Eagle, D, Bankala, K, Robinson, S.D. 登録日 2021-06-23 公開日 2022-02-09 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals. Proc.Natl.Acad.Sci.USA, 119, 2022
4YQU	Glutathione S-transferase Omega 1 bound to covalent inhibitor C1-31 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Glutathione S-transferase omega-1, N-{5-(azepan-1-ylsulfonyl)-2-[(ethylsulfanyl)methoxy]phenyl}acetamide 著者 Stuckey, J.A. 登録日 2015-03-13 公開日 2016-10-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.94 Å) 主引用文献 Mechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor. Nat Commun, 7, 2016
7SFW	CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 (focus refine of the asymmetric unit) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ... 著者 Binshtein, E, Crowe, J.E. 登録日 2021-10-04 公開日 2022-03-16 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022
7SFU	CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ... 著者 Binshtein, E, Crowe, J.E. 登録日 2021-10-04 公開日 2022-03-16 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022
7SFV	CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ... 著者 Binshtein, E, Crowe, J.E. 登録日 2021-10-04 公開日 2022-03-16 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022
6KEI	Crystal structure of BRD4 bromodomain 1 (BD1) in complex with 16-methoxy-11-methyl-6-[(pyridin-2-yl)methoxy]-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(16),3,5,7,9,13(17),14-heptaen-12-one 分子名称: 16-methoxy-11-methyl-6-[(pyridin-2-yl)methoxy]-2-oxa-11-azatetracyclo[8.6.1.03,8.013,17]heptadeca-1(16),3,5,7,9,13(17),14-heptaen-12-one, Bromodomain-containing protein 4, FORMIC ACID 著者 Lee, B.I, Park, T.H. 登録日 2019-07-04 公開日 2020-07-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.451 Å) 主引用文献 Synthesis and Structure-Activity Relationships of Aristoyagonine Derivatives as Brd4 Bromodomain Inhibitors with X-ray Co-Crystal Research. Molecules, 26, 2021
6KSY	Crystal structure of arginase from Zymomonas mobilis ZM4 分子名称: Arginase/agmatinase/formiminoglutamase, ZINC ION 著者 Park, S.Y, Hwangbo, S.A. 登録日 2019-08-26 公開日 2020-08-05 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.649 Å) 主引用文献 Characterization of a Dimeric Arginase FromZymomonas mobilisZM4. Front Microbiol, 10, 2019
6KU6	OSM1 mutant - R326A 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Fumarate reductase 2, SUCCINIC ACID 著者 Park, H.H, Kim, C.M. 登録日 2019-08-30 公開日 2020-07-08 実験手法 X-RAY DIFFRACTION (2.007 Å) 主引用文献 Crystal Structure of the Active Site Mutant Form of Soluble Fumarate Reductase, Osm1 Crystals, 2019
4ZKJ	Crystal structure of CRISPR-associated protein 分子名称: CRISPR-associated protein Cas1, GLYCEROL 著者 Ka, D, Bae, E. 登録日 2015-04-30 公開日 2016-01-13 最終更新日 2016-01-20 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Streptococcus pyogenes Cas1 and Its Interaction with Csn2 in the Type II CRISPR-Cas System Structure, 24, 2016
7S24	Crystal structure of the Na+/H+ antiporter NhaA at pH 6.5 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Na(+)/H(+) antiporter NhaA, PENTAETHYLENE GLYCOL 著者 Drew, D, Brock, J, Uzdavinys, P, Matsuoka, R. 登録日 2021-09-03 公開日 2022-08-10 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of the Na + /H + antiporter NhaA at active pH reveals the mechanistic basis for pH sensing. Nat Commun, 13, 2022

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