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7QS6

Solution structure of thanatin-like derivative 7 in complex with E.coli LptA

Summary for 7QS6
Entry DOI10.2210/pdb7qs6/pdb
NMR InformationBMRB: 34699
DescriptorLipopolysaccharide export system protein LptA, Thanatin-like derivative (2 entities in total)
Functional Keywordsstructure from cyana 3.98.11, antibiotic
Biological sourceEscherichia coli K-12
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Total number of polymer chains2
Total formula weight14875.69
Authors
Moehle, K.,Zerbe, O. (deposition date: 2022-01-12, release date: 2023-05-10, Last modification date: 2023-11-15)
Primary citationSchuster, M.,Brabet, E.,Oi, K.K.,Desjonqueres, N.,Moehle, K.,Le Poupon, K.,Hell, S.,Gable, S.,Rithie, V.,Dillinger, S.,Zbinden, P.,Luther, A.,Li, C.,Stiegeler, S.,D'Arco, C.,Locher, H.,Remus, T.,DiMaio, S.,Motta, P.,Wach, A.,Jung, F.,Upert, G.,Obrecht, D.,Benghezal, M.,Zerbe, O.
Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae.
Sci Adv, 9:eadg3683-eadg3683, 2023
Cited by
PubMed: 37224246
DOI: 10.1126/sciadv.adg3683
PDB entries with the same primary citation
Experimental method
SOLUTION NMR
Structure validation

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