PDB: 217477 件ウェブページステータス検索Chemie searchBIRD

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2M7R	Nmda receptor antagonist, conantokin bk-b, nmr, 20 structure 分子名称: CONANTOKIN BK-B 著者 Curtice, K.J, Platt, R.J, Skalicky, J.J, Horvath, M.P, Twede, V.D. 登録日 2013-04-29 公開日 2014-02-19 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 From molecular phylogeny towards differentiating pharmacology for NMDA receptor subtypes. Toxicon, 81C, 2014
1SQV	Crystal Structure Analysis of Bovine Bc1 with UHDBT 分子名称: 6-HYDROXY-5-UNDECYL-1,3-BENZOTHIAZOLE-4,7-DIONE, Cytochrome b, Cytochrome c1, ... 著者 Esser, L, Quinn, B, Li, Y.F, Zhang, M, Elberry, M, Yu, L, Yu, C.A, Xia, D. 登録日 2004-03-19 公開日 2005-09-06 最終更新日 2021-03-03 実験手法 X-RAY DIFFRACTION (2.85 Å) 主引用文献 Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex. J.Mol.Biol., 341, 2004
305D	SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICATATIC) IN THE TETRAGONAL FORM 分子名称: DISTAMYCIN A, DNA (5'-D(*IP*CP*AP*TP*AP*TP*IP*C)-3'), MAGNESIUM ION 著者 Chen, X, Ramakrishnan, B, Sundaralingam, M. 登録日 1997-01-03 公開日 1997-09-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.17 Å) 主引用文献 Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC). J.Mol.Biol., 267, 1997
2MWR	Solution Structure of Acidocin B, a Circular Bacteriocin from Lactobacillus acidophilus M46 分子名称: Acidocin B 著者 Vederas, J.C, Acedo, J.Z, van Belkum, M.J, Lohans, C.T. 登録日 2014-11-19 公開日 2015-03-04 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 Solution Structure of Acidocin B, a Circular Bacteriocin Produced by Lactobacillus acidophilus M46. Appl.Environ.Microbiol., 81, 2015
306D	SIDE-BY-SIDE BINDING OF DISTAMYCIN MOLECULES TO D(ICITACIC) 分子名称: DISTAMYCIN A, DNA (5'-D(*IP*CP*IP*TP*AP*CP*IP*C)-3'), MAGNESIUM ION 著者 Chen, X, Ramakrishnan, B, Sundaralingam, M. 登録日 1997-01-03 公開日 1997-09-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Crystal structures of the side-by-side binding of distamycin to AT-containing DNA octamers d(ICITACIC) and d(ICATATIC). J.Mol.Biol., 267, 1997
3NAM	SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative dOTg 分子名称: (3S,3aR,4S,6S,6aS,8R,9R,9aR,9bS)-6-(acetyloxy)-4-(butanoyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-2-oxododecahydroazuleno[4,5-b]furan-8-yl (2Z)-2-methylbut-2-enoate, MAGNESIUM ION, PHOSPHATIDYLETHANOLAMINE, ... 著者 Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. 登録日 2010-06-02 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs J.Biol.Chem., 285, 2010
3NAL	SR Ca(2+)-ATPase in the HnE2 state complexed with the Thapsigargin derivative DTB 分子名称: (3S,3aR,4S,6S,6aS,8R,9bS)-6-(acetyloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-4-yl dodecanoate, MAGNESIUM ION, POTASSIUM ION, ... 著者 Winther, A.M.L, Sonntag, Y, Olesen, C, Moller, J.V, Nissen, P. 登録日 2010-06-02 公開日 2010-06-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Critical roles of hydrophobicity and orientation of side chains for inactivation of sarcoplasmic reticulum Ca2+-ATPase with thapsigargin and thapsigargin analogs J.Biol.Chem., 285, 2010
4E2I	The Complex Structure of the SV40 Helicase Large T Antigen and p68 Subunit of DNA Polymerase Alpha-Primase 分子名称: DNA polymerase alpha subunit B, Large T antigen, ZINC ION 著者 Zhou, B, Arnett, D.R, Yu, X, Brewster, A, Sowd, G.A, Xie, C.L, Vila, S, Gai, D, Fanning, E, Chen, X.S. 登録日 2012-03-08 公開日 2012-06-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (5 Å) 主引用文献 Structural basis for the interaction of a hexameric replicative helicase with the regulatory subunit of human DNA polymerase alpha-primase. J.Biol.Chem., 287, 2012
5U1I	Crystal structure of a methyltransferase involved in the biosynthesis of gentamicin in complex with the methylated Kanamycin B 分子名称: (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-3-(methylamino)-alpha-D-glucopyranosyl]oxy}-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, CALCIUM ION, Putative gentamicin methyltransferase, ... 著者 Bury, P, Huang, F, Leadlay, P, Dias, M.V.B. 登録日 2016-11-28 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.932 Å) 主引用文献 Structural Basis of the Selectivity of GenN, an Aminoglycoside N-Methyltransferase Involved in Gentamicin Biosynthesis. ACS Chem. Biol., 12, 2017
2UVX	Structure of PKA-PKB chimera complexed with 7-azaindole 分子名称: 1H-PYRROLO[2,3-B]PYRIDINE, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, CAMP-DEPENDENT PROTEIN KINASE, ... 著者 Davies, T.G, Donald, A, McHardy, T, Rowlands, M.G, Hunter, L.J, Boyle, R.G, Aherne, G.W, Garrett, M.D, Collins, I. 登録日 2007-03-15 公開日 2007-05-08 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B Through Structure-Based Design J.Med.Chem., 50, 2007
4QHL	I3.2 (unbound) from CH103 Lineage 分子名称: I3 heavy chain, UCA light chain 著者 Fera, D, Harrison, S.C. 登録日 2014-05-28 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.153 Å) 主引用文献 Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
1WAV	CRYSTAL STRUCTURE OF FORM B MONOCLINIC CRYSTAL OF INSULIN 分子名称: INSULIN, PHENOL, ZINC ION 著者 Liang, D.-C, Ding, J.-H, Chang, W.-R, Wan, Z.-L. 登録日 1996-02-28 公開日 1997-02-28 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular replacement study on form-B monoclinic crystal of insulin. Sci.China, Ser.C: Life Sci., 39, 1996
2YGL	The X-ray crystal structure of tandem CBM51 modules of Sp3GH98, the family 98 glycoside hydrolase from Streptococcus pneumoniae SP3-BS71 分子名称: BLOOD GROUP A-AND B-CLEAVING ENDO-BETA-GALACTOSIDASE, CALCIUM ION 著者 Higgins, M.A, Ficko-Blean, E, Wright, C, Meloncelli, P.J, Lowary, T.L, Boraston, A.B. 登録日 2011-04-18 公開日 2011-06-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Overall Architecture and Receptor Binding of Pneumococcal Carbohydrate Antigen Hydrolyzing Enzymes. J.Mol.Biol., 411, 2011
1B5B	RAT FERROCYTOCHROME B5 B CONFORMATION, NMR, 1 STRUCTURE 分子名称: FERROCYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE 著者 Dangi, B, Sarma, S, Yan, C, Banville, D, Guiles, R.D. 登録日 1998-04-06 公開日 1998-06-17 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 The origin of differences in the physical properties of the equilibrium forms of cytochrome b5 revealed through high-resolution NMR structures and backbone dynamic analyses. Biochemistry, 37, 1998
4EJ4	Structure of the delta opioid receptor bound to naltrindole 分子名称: (4bS,8R,8aS,14bR)-7-(cyclopropylmethyl)-5,6,7,8,14,14b-hexahydro-4,8-methano[1]benzofuro[2,3-a]pyrido[4,3-b]carbazole-1,8a(9H)-diol, Delta-type opioid receptor, Lysozyme chimera 著者 Granier, S, Manglik, A, Kruse, A.C, Kobilka, T.S, Thian, F.S, Weis, W.I, Kobilka, B.K. 登録日 2012-04-06 公開日 2012-05-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structure of the delta opioid receptor bound to naltrindole Nature, 485, 2012
2ORX	Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin 分子名称: Neuropilin-1 著者 Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. 登録日 2007-02-05 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural basis for ligand and heparin binding to neuropilin B domains Proc.Natl.Acad.Sci.Usa, 104, 2007
2JET	Crystal structure of a trypsin-like mutant (S189D , A226G) chymotrypsin. 分子名称: CHYMOTRYPSINOGEN B CHAIN A, CHYMOTRYPSINOGEN B CHAIN B, CHYMOTRYPSINOGEN B CHAIN C 著者 Jelinek, B, Katona, G, Fodor, K, Venekei, I, Graf, L. 登録日 2007-01-22 公開日 2007-09-18 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The Crystal Structure of a Trypsin-Like Mutant Chymotrypsin: The Role of Position 226 in the Activity and Specificity of S189D Chymotrypsin. Protein J., 27, 2008
2YPL	Structural features underlying T-cell receptor sensitivity to concealed MHC class I micropolymorphisms 分子名称: AGA T-CELL RECEPTOR ALPHA CHAIN, AGA T-CELL RECEPTOR BETA CHAIN, BETA-2-MICROGLOBULIN, ... 著者 Stewart-Jones, G.B, Simpson, P, van der Merwe, P.A, Easterbrook, P, McMichael, A.J, Rowland-Jones, S.L, Jones, E.Y, Gillespie, G.M. 登録日 2012-10-30 公開日 2012-11-28 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structural Features Underlying T-Cell Receptor Sensitivity to Concealed Mhc Class I Micropolymorphisms. Proc.Natl.Acad.Sci.USA, 109, 2012
3OE6	Crystal structure of the CXCR4 chemokine receptor in complex with a small molecule antagonist IT1t in I222 spacegroup 分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate, C-X-C chemokine receptor type 4, ... 著者 Wu, B, Mol, C.D, Han, G.W, Katritch, V, Chien, E.Y.T, Liu, W, Cherezov, V, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) 登録日 2010-08-12 公開日 2010-10-27 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Science, 330, 2010
2ORZ	Structural Basis for Ligand Binding and Heparin Mediated Activation of Neuropilin 分子名称: Neuropilin-1, Tuftsin 著者 Vander Kooi, C.W, Jusino, M.A, Perman, B, Neau, D.B, Bellamy, H.D, Leahy, D.J. 登録日 2007-02-05 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural basis for ligand and heparin binding to neuropilin B domains. Proc.Natl.Acad.Sci.Usa, 104, 2007
1YQY	Structure of B. Anthrax Lethal factor in complex with a hydroxamate inhibitor 分子名称: (2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE, Lethal factor, ZINC ION 著者 Shoop, W.L, Xiong, Y, Wiltsie, J, Woods, A, Guo, J, Pivnichny, J.V, Felcetto, T, Michael, B.F, Bansal, A. 登録日 2005-02-02 公開日 2005-05-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Anthrax lethal factor inhibition. Proc.Natl.Acad.Sci.Usa, 102, 2005
1XOZ	Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Tadalafil 分子名称: 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE, MAGNESIUM ION, ZINC ION, ... 著者 Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. 登録日 2004-10-07 公開日 2004-12-14 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12, 2004
7FAR	Crystal structure of PDE5A in complex with inhibitor L12 分子名称: 5-[bis(fluoranyl)methoxy]-2-[(4-chlorophenyl)methyl]-10-(3-methoxypropyl)-3,10-diazatricyclo[6.4.1.0^{4,13}]trideca-1,4(13),5,7-tetraen-9-one, MAGNESIUM ION, ZINC ION, ... 著者 Wu, D, Huang, Y.Y, Luo, H.B. 登録日 2021-07-07 公開日 2022-05-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.40006471 Å) 主引用文献 Free energy perturbation (FEP)-guided scaffold hopping. Acta Pharm Sin B, 12, 2022
1BXH	CONCANAVALIN A COMPLEXED TO METHYL ALPHA1-2 MANNOBIOSIDE 分子名称: CALCIUM ION, Concanavalin-A, MANGANESE (II) ION, ... 著者 Moothoo, D.N, Canaan, B, Field, R.A, Naismith, J.H. 登録日 1998-10-02 公開日 1998-10-07 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Man alpha1-2 Man alpha-OMe-concanavalin A complex reveals a balance of forces involved in carbohydrate recognition. Glycobiology, 9, 1999
3B3I	Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes 分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... 著者 Beltrami, A, Rossmann, M, Fiorillo, M.T, Paladini, F, Sorrentino, R, Saenger, W, Kumar, P, Ziegler, A, Uchanska-Ziegler, B. 登録日 2007-10-22 公開日 2008-07-22 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes. J.Biol.Chem., 283, 2008

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