1YQY
Structure of B. Anthrax Lethal factor in complex with a hydroxamate inhibitor
Summary for 1YQY
Entry DOI | 10.2210/pdb1yqy/pdb |
Descriptor | Lethal factor, ZINC ION, (2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE, ... (4 entities in total) |
Functional Keywords | toxin, lethal factor, inhibitors, hydroxamate, hydrolase |
Biological source | Bacillus anthracis |
Cellular location | Secreted: P15917 |
Total number of polymer chains | 1 |
Total formula weight | 61249.33 |
Authors | Shoop, W.L.,Xiong, Y.,Wiltsie, J.,Woods, A.,Guo, J.,Pivnichny, J.V.,Felcetto, T.,Michael, B.F.,Bansal, A. (deposition date: 2005-02-02, release date: 2005-05-31, Last modification date: 2023-08-23) |
Primary citation | Shoop, W.L.,Xiong, Y.,Wiltsie, J.,Woods, A.,Guo, J.,Pivnichny, J.V.,Felcetto, T.,Michael, B.F.,Bansal, A.,Cummings, R.T.,Cunningham, B.R.,Friedlander, A.M.,Douglas, C.M.,Patel, S.B.,Wisniewski, D.,Scapin, G.,Salowe, S.P.,Zaller, D.M.,Chapman, K.T.,Scolnick, E.M.,Schmatz, D.M.,Bartizal, K.,MacCoss, M.,Hermes, J.D. Anthrax lethal factor inhibition. Proc.Natl.Acad.Sci.Usa, 102:7958-7963, 2005 Cited by PubMed: 15911756DOI: 10.1073/pnas.0502159102 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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