1YQY
Structure of B. Anthrax Lethal factor in complex with a hydroxamate inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lethal factor | polymer | 523 | 60837.6 | 1 | UniProt (P15917) Pfam (PF09156) Pfam (PF07737) | Bacillus anthracis | LF, Anthrax lethal toxin endopeptidase component |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | (2R)-2-{[(4-FLUORO-3-METHYLPHENYL)SULFONYL]AMINO}-N-HYDROXY-2-TETRAHYDRO-2H-PYRAN-4-YLACETAMIDE | non-polymer | 346.4 | 1 | Chemie (915) PubChem (45267142) PubChem (10337670) PubChem (4369384) | |||
| 4 | D (A) | water | water | 18.0 | 436 | Chemie (HOH) |
Sequence modifications
A: 264 - 776 (UniProt: P15917)
| PDB | External Database | Details |
|---|---|---|
| Gly 258 | - | cloning artifact |
| Ser 259 | - | cloning artifact |
| Lys 260 | - | cloning artifact |
| Asp 261 | - | cloning artifact |
| Pro 262 | - | cloning artifact |
| Gly 263 | - | cloning artifact |
| Ser 266 | Ala 299 | variant |
| Leu 777 | - | cloning artifact |
| Val 778 | - | cloning artifact |
| Pro 779 | - | cloning artifact |
| Arg 780 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 60837.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 411.8 | |
| All* | Total formula weight | 61249.3 |
