Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2UVX

Structure of PKA-PKB chimera complexed with 7-azaindole

Summary for 2UVX
Entry DOI10.2210/pdb2uvx/pdb
Related1CMK 1KMU 1KMW 1Q24 1Q61 1Q62 1Q8T 1Q8U 1Q8W 1SMH 1STC 1SVE 1SVG 1SVH 1SZM 1VEB 1XH4 1XH5 1XH6 1XH7 1XH8 1XH9 1XHA 1YDR 1YDS 1YDT 2C1A 2C1B 2F7E 2GFC 2GNF 2GNG 2GNH 2GNI 2GNJ 2GNL 2JDS 2JDT 2JDV 2UVY 2UVZ 2UW0
DescriptorCAMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT, CAMP-DEPENDENT PROTEIN KINASE INHIBITOR ALPHA, 1H-PYRROLO[2,3-B]PYRIDINE, ... (4 entities in total)
Functional Keywordstransferase/inhibitor, camp, kinase, myristate, transferase, lipoprotein, serine/threonine-protein kinase, transferase-inhibitor complex, nucleotide-binding, protein kinase inhibitor, atp- binding, nuclear protein, phosphorylation
Biological sourceBOS TAURUS (BOVINE)
More
Cellular locationCytoplasm: P00517
Total number of polymer chains2
Total formula weight43175.16
Authors
Davies, T.G.,Donald, A.,McHardy, T.,Rowlands, M.G.,Hunter, L.J.,Boyle, R.G.,Aherne, G.W.,Garrett, M.D.,Collins, I. (deposition date: 2007-03-15, release date: 2007-05-08, Last modification date: 2011-07-13)
Primary citationDonald, A.,Mchardy, T.,Rowlands, M.G.,Hunter, L.J.,Davies, T.G.,Berdini, V.,Boyle, R.G.,Aherne, G.W.,Garrett, M.D.,Collins, I.
Rapid Evolution of 6-Phenylpurine Inhibitors of Protein Kinase B Through Structure-Based Design
J.Med.Chem., 50:2289-, 2007
Cited by
PubMed: 17451235
DOI: 10.1021/JM0700924
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon