2GFC

cAMP-dependent protein kinase PKA catalytic subunit with PKI-5-24

Summary for 2GFC

Entry DOI	10.2210/pdb2gfc/pdb
Descriptor	cAMP-dependent protein kinase, alpha-catalytic subunit, cAMP-dependent protein kinase inhibitor alpha, N-OCTANE, ... (4 entities in total)
Functional Keywords	binary complex, peptide inhibitor, transferase
Biological source	Bos taurus (cattle) More
Cellular location	Cytoplasm: P00517
Total number of polymer chains	2
Total formula weight	43047.06
Authors	Bonn, S.,Herrero, S.,Breitenlechner, C.B.,Engh, R.A.,Gassel, M.,Bossemeyer, D. (deposition date: 2006-03-21, release date: 2006-05-23, Last modification date: 2024-04-03)
Primary citation	Bonn, S.,Herrero, S.,Breitenlechner, C.B.,Erlbruch, A.,Lehmann, W.,Engh, R.A.,Gassel, M.,Bossemeyer, D. Structural Analysis of Protein Kinase A Mutants with Rho-kinase Inhibitor Specificity. J.Biol.Chem., 281:24818-24830, 2006 Cited by PubMed: 16699172 DOI: 10.1074/jbc.M512374200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation