2GAZ
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![BU of 2gaz by Molmil](/molmil-images/mine/2gaz) | Mycobacterial lipoglycan presentation by CD1d | 分子名称: | (2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPAN E-1,2-DIYL DIHEXADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, T-cell surface glycoprotein CD1d1, ... | 著者 | Zajonc, D.M. | 登録日 | 2006-03-09 | 公開日 | 2006-09-26 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d. J.Immunol., 177, 2006
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4D3C
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![BU of 4d3c by Molmil](/molmil-images/mine/4d3c) | |
5IUE
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![BU of 5iue by Molmil](/molmil-images/mine/5iue) | |
5BRZ
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![BU of 5brz by Molmil](/molmil-images/mine/5brz) | MAGE-A3 reactive TCR in complex with MAGE-A3 in HLA-A1 | 分子名称: | Beta-2-microglobulin, GLU-VAL-ASP-PRO-ILE-GLY-HIS-LEU-TYR, HLA class I histocompatibility antigen, ... | 著者 | Raman, M.C.C, Rizkallah, P.J, Simmons, R, Donnellan, Z, Dukes, J, Bossi, G, LeProvost, G, Mahon, T, Hickman, E, LomaX, M, Oates, J, Hassan, N, Vuidepot, A, Sami, M, Cole, D.K, Jakobsen, B.K. | 登録日 | 2015-06-01 | 公開日 | 2016-03-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.62 Å) | 主引用文献 | Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy. Sci Rep, 6, 2016
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6GL1
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![BU of 6gl1 by Molmil](/molmil-images/mine/6gl1) | HLA-E*01:03 in complex with the HIV epitope, RL9HIV | 分子名称: | ARG-MET-TYR-SER-PRO-THR-SER-ILE-LEU, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Walters, L.C, Gillespie, G.M, McMichael, A.J, Rozbesky, D, Jones, E.Y, Harlos, K. | 登録日 | 2018-05-22 | 公開日 | 2018-08-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.623 Å) | 主引用文献 | Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding. Nat Commun, 9, 2018
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7DZN
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![BU of 7dzn by Molmil](/molmil-images/mine/7dzn) | |
8ZCM
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![BU of 8zcm by Molmil](/molmil-images/mine/8zcm) | Cryogenic Temperature Crystal Structure of Fc Fragment of Human IgG1 from Biosimilar VEGF-Trap | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Immunoglobulin gamma-1 heavy chain, ... | 著者 | Destan, E, DeMirci, H. | 登録日 | 2024-04-30 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Cryogenic Temperature Crystal Structure of Fc Fragment of Human IgG1 from Biosimilar VEGF-Trap To Be Published
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7OW6
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![BU of 7ow6 by Molmil](/molmil-images/mine/7ow6) | |
8TBV
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![BU of 8tbv by Molmil](/molmil-images/mine/8tbv) | Human Class I MHC HLA-A2 in complex with sorting nexin 24 (127-135) neoantigen KLSHQLVLL | 分子名称: | Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Arbuiso, A, Weiss, L.I, Brambley, C.A, Ma, J, Keller, G.L.J, Ayres, C.M, Baker, B.M. | 登録日 | 2023-06-29 | 公開日 | 2024-01-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Accurate modeling of peptide-MHC structures with AlphaFold. Structure, 32, 2024
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5WET
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![BU of 5wet by Molmil](/molmil-images/mine/5wet) | Crystal Structure of H2-Dd with disulfide-linked 6mer peptide | 分子名称: | Beta-2-microglobulin, GLYCINE, H-2 class I histocompatibility antigen, ... | 著者 | Jiang, J.S, Natarajan, K, Boyd, L.F, Margulies, D.H. | 登録日 | 2017-07-10 | 公開日 | 2017-10-18 | 最終更新日 | 2017-12-13 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Crystal structure of a TAPBPR-MHC I complex reveals the mechanism of peptide editing in antigen presentation. Science, 358, 2017
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4L3C
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![BU of 4l3c by Molmil](/molmil-images/mine/4l3c) | Structure of HLA-A2 in complex with D76N b2m mutant and NY-ESO1 double mutant | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | 著者 | Halabelian, L, Giorgetti, S, Bellotti, V, Bolognesi, M, Ricagno, S. | 登録日 | 2013-06-05 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic beta 2-Microglobulin. J.Biol.Chem., 289, 2014
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5IRO
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![BU of 5iro by Molmil](/molmil-images/mine/5iro) | |
7BBG
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![BU of 7bbg by Molmil](/molmil-images/mine/7bbg) | CRYSTAL STRUCTURE OF HLA-A2-WT1-RMF AND FAB 11D06 | 分子名称: | Beta-2-microglobulin, Heavy chain of Fab fragment 11D06, Light chain of Fab fragment 11D06, ... | 著者 | Bujotzek, A, Georges, G, Hanisch, L.J, Klein, C, Benz, J. | 登録日 | 2020-12-17 | 公開日 | 2021-10-27 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Targeting intracellular WT1 in AML with a novel RMF-peptide-MHC-specific T-cell bispecific antibody. Blood, 138, 2021
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4NQS
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![BU of 4nqs by Molmil](/molmil-images/mine/4nqs) | Knob-into-hole IgG Fc | 分子名称: | Ig gamma-1 chain C region, miniZ | 著者 | Eigenbrot, C, Ultsch, M. | 登録日 | 2013-11-25 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Antiparallel Conformation of Knob and Hole Aglycosylated Half-Antibody Homodimers Is Mediated by a CH2-CH3 Hydrophobic Interaction. J.Mol.Biol., 426, 2014
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6ZKY
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![BU of 6zky by Molmil](/molmil-images/mine/6zky) | Crystal structure of InhA:01 TCR in complex with HLA-E (S147C) bound to InhA (53-61 H3C) | 分子名称: | Beta-2-microglobulin, Enoyl-[acyl-carrier-protein] reductase [NADH], HLA class I histocompatibility antigen, ... | 著者 | Srikannathasan, V, Karuppiah, V, Robinson, R.A. | 登録日 | 2020-06-30 | 公開日 | 2022-01-26 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition. Eur.J.Immunol., 52, 2022
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8ES8
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1FFO
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![BU of 1ffo by Molmil](/molmil-images/mine/1ffo) | CRYSTAL STRUCTURE OF MURINE CLASS I H-2DB COMPLEXED WITH SYNTHETIC PEPTIDE GP33 (C9M/K1A) | 分子名称: | BETA-2 MICROGLOBULIN BETA CHAIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN, D-B, ... | 著者 | Wang, B, Sharma, A, Maile, R, Saad, M, Collins, E.J, Frelinger, J.A. | 登録日 | 2000-07-25 | 公開日 | 2002-12-11 | 最終更新日 | 2017-02-01 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Peptidic termini play a significant role in TCR recognition. J.Immunol., 169, 2002
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8TRR
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![BU of 8trr by Molmil](/molmil-images/mine/8trr) | T cell recognition of citrullinated vimentin peptide presented by HLA-DR4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Loh, T.J, Lim, J.J, Reid, H.H, Rossjohn, J. | 登録日 | 2023-08-10 | 公開日 | 2024-07-31 | 最終更新日 | 2024-08-07 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nat Commun, 15, 2024
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5SWZ
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![BU of 5swz by Molmil](/molmil-images/mine/5swz) | Crystal Structure of NP1-B17 TCR-H2Db-NP complex | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, D-B alpha chain, ... | 著者 | Gras, S, Del Campo, C.M, Farenc, C, Josephs, T.M, Rossjohn, J. | 登録日 | 2016-08-09 | 公開日 | 2016-10-05 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response. Immunity, 45, 2016
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4WI9
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![BU of 4wi9 by Molmil](/molmil-images/mine/4wi9) | Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc mutation I253A/H310A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, ... | 著者 | Farrugia, W, Burvenich, I.J.G, Scott, A.M, Ramsland, P.A. | 登録日 | 2014-09-25 | 公開日 | 2015-09-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structural and functional mapping of human IgG1 binding site for FcRn in vivo using human FcRn transgenic mice To Be Published
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2VE6
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![BU of 2ve6 by Molmil](/molmil-images/mine/2ve6) | Crystal structure of a Murine MHC class I H2-Db molecule in complex with a photocleavable peptide | 分子名称: | BETA-2-MICROGLOBULIN, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, SENDAI VIRUS EPITOPE RESIDUES 324-332 MODIFIED AT P7 | 著者 | Grotenbreg, G.M, Roan, N.R, Guillen, E, Meijers, R, Wang, J.H, Bell, G.W, Starnbach, M.N, Ploegh, H.L. | 登録日 | 2007-10-17 | 公開日 | 2008-01-22 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Discovery of Cd8+ T Cell Epitopes in Chlamydia Trachomatis Infection Through Use of Caged Class I Mhc Tetramers. Proc.Natl.Acad.Sci.USA, 105, 2008
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7Z50
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![BU of 7z50 by Molmil](/molmil-images/mine/7z50) | |
8QH1
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![BU of 8qh1 by Molmil](/molmil-images/mine/8qh1) | |
4Z7V
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![BU of 4z7v by Molmil](/molmil-images/mine/4z7v) | L3-12 complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-alpha chain, MHC class II HLA-DQ-beta-1, ... | 著者 | Petersen, J, Rossjohn, J, Reid, H.H, Koning, F. | 登録日 | 2015-04-08 | 公開日 | 2015-06-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Determinants of Gliadin-Specific T Cell Selection in Celiac Disease. J Immunol., 194, 2015
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6CXA
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![BU of 6cxa by Molmil](/molmil-images/mine/6cxa) | |