7DZN

Crystal Structure of the cross-restricted T18A TCR and HLAB4201 bound to HIV-1 Gag TL9 peptide

Summary for 7DZN

• Entry DOI: 10.2210/pdb7dzn/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, Gag-Pol polyprotein, ... (6 entities in total)
• Functional Keywords: tcr and p-mhc complex, hiv epitope tl9, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 5
• Total formula weight: 95352.95

Authors

Liu, Y.,Yin, L. (deposition date: 2021-01-25, release date: 2022-01-26, Last modification date: 2023-11-29)

• Primary citation: Liu, Y.,San, D.,Yin, L.; Cross-reactive TCR with alloreactivity for immunodominant HIV-1 epitope Gag TL9 with enhanced control of viral infection; Biorxiv, 2021; DOI: 10.1101/2021.06.06.447276

Experimental method

X-RAY DIFFRACTION (2.63 Å)