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7DZN

Crystal Structure of the cross-restricted T18A TCR and HLAB4201 bound to HIV-1 Gag TL9 peptide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
MHC class I antigenpolymer27932205.31UniProt (V6E0U6)
Pfam (PF00129)
Pfam (PF07654)
Homo sapiens (Human)
2B
(B)
Beta-2-microglobulinpolymer10011879.41UniProt (P61769)
Pfam (PF07654)
Homo sapiens (Human)
3C
(C)
Gag-Pol polyproteinpolymer91032.21UniProt (P03367)
UniProt (by SIFTS) (P04585)
Human immunodeficiency virus 1
4D
(D)
beta chain T18A TCRpolymer24427566.81Homo sapiens (Human)
5E
(E)
alpha chain T18A TCRpolymer20422669.31Homo sapiens (Human)
6F, G, H, I, J
(A, B, C, D, E)
waterwater18.0116Chemie (HOH)
Sequence modifications
A: 3 - 279 (UniProt: V6E0U6)
PDBExternal DatabaseDetails
Met 1-expression tag
Gly 2-expression tag
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight95352.9
All*Total formula weight95352.9
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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