4D3C

Crystal structure of the NK1 domain of HGF in complex with anti-HGF monoclonal antibody SFN68.

Summary for 4D3C

• Entry DOI: 10.2210/pdb4d3c/pdb
• Descriptor: HEPATOCYTE GROWTH FACTOR, SFN68 FAB, ... (4 entities in total)
• Functional Keywords: protein binding
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 3
• Total formula weight: 68447.68

Authors

Kang, Y.J.,Kim, K.L.,Cho, H.S.,Chung, J.H. (deposition date: 2014-10-21, release date: 2016-01-13, Last modification date: 2023-12-20)

• Primary citation: Kang, Y.J.,Kim, K.L.,Cho, H.S.,Chung, J.H.; A mechanistic basis for converting a receptor tyrosine kinase agonist to an antagonist.; to be published,

Experimental method

X-RAY DIFFRACTION (2.62 Å)