5SWZ

Crystal Structure of NP1-B17 TCR-H2Db-NP complex

Summary for 5SWZ

• Entry DOI: 10.2210/pdb5swz/pdb
• Related: 5SWS
• Descriptor: H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, influenza NP366 epitope, ... (8 entities in total)
• Functional Keywords: h2db, influenza, np366, reversed docking, naive t cell, np1-b17 tcr, tcr, t cell, immune system
• Biological source: Mus musculus (Mouse); More
• Cellular location: Membrane; Single-pass type I membrane protein: P01899; Secreted: P01887
• Total number of polymer chains: 20
• Total formula weight: 385186.72

Authors

Gras, S.,Del Campo, C.M.,Farenc, C.,Josephs, T.M.,Rossjohn, J. (deposition date: 2016-08-09, release date: 2016-10-05, Last modification date: 2023-10-04)

• Primary citation: Gras, S.,Chadderton, J.,Del Campo, C.M.,Farenc, C.,Wiede, F.,Josephs, T.M.,Sng, X.Y.,Mirams, M.,Watson, K.A.,Tiganis, T.,Quinn, K.M.,Rossjohn, J.,La Gruta, N.L.; Reversed T Cell Receptor Docking on a Major Histocompatibility Class I Complex Limits Involvement in the Immune Response.; Immunity, 45:749-760, 2016; PubMed: 27717799; DOI: 10.1016/j.immuni.2016.09.007

Experimental method

X-RAY DIFFRACTION (2.65 Å)