PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

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2LDU	Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C 分子名称: Heat shock factor protein 1 著者 Liu, G, Xiao, R, Ciccosanti, C, Janjua, H, Acton, T.B, Lee, H, Wang, H.B, Huang, Y.B, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) 登録日 2011-06-01 公開日 2011-07-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Northeast Structural Genomics Consortium Target HR3023C To be Published
6QU7	Crystal structure of human DHODH in complex with BAY 2402234 分子名称: ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... 著者 Friberg, A, Gradl, S. 登録日 2019-02-26 公開日 2019-06-05 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia, 33, 2019
2L02	Solution NMR Structure of protein BT2368 from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR375 分子名称: Uncharacterized protein 著者 Eletsky, A, Lee, H, Wang, D, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) 登録日 2010-06-29 公開日 2010-08-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of protein BT2368 from Bacteroides thetaiotaomicron To be Published
6QUC	Truncated beta-galactosidase III from Bifidobacterium bifidum 分子名称: Beta-galactosidase, CALCIUM ION, IMIDAZOLE 著者 Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. 登録日 2019-02-27 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Truncated beta-galactosidase III from Bifidobacterium bifidum To Be Published
2LIU	NMR structure of holo-ACPI domain from CurA module from Lyngbya majuscula 分子名称: CurA 著者 Busche, A.E, Gottstein, D, Hein, C, Ripin, N, Pader, I, Tufar, P, Eisman, E.B, Gu, L, Walsh, C.T, Loehr, F, Sherman, D.H, Guntert, P, Dotsch, V. 登録日 2011-09-01 公開日 2011-12-14 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Characterization of Molecular Interactions between ACP and Halogenase Domains in the Curacin A Polyketide Synthase. Acs Chem.Biol., 7, 2012
2LKL	Structure of the core intracellular domain of PfEMP1 分子名称: Erythrocyte membrane protein 1 (PfEMP1) 著者 Vakonakis, I, Erat, M.C. 登録日 2011-10-16 公開日 2012-01-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural Analysis of the Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Intracellular Domain Reveals a Conserved Interaction Epitope. J.Biol.Chem., 287, 2012
6QUT	Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide 分子名称: 4-chloranyl-~{N}-(3-oxidanylpropyl)-2-phenylsulfanyl-5-sulfamoyl-benzamide, Carbonic anhydrase 9, ZINC ION 著者 Leitans, J, Tars, K. 登録日 2019-02-28 公開日 2020-03-25 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur.J.Med.Chem., 185, 2020
5KP9	Structure of Nanoparticle Released from Enveloped Protein Nanoparticle 分子名称: EPN-01* 著者 Votteler, J, Ogohara, C, Yi, S, Hsia, Y, Natterman, U, Belnap, D.M, King, N.P, Sundquist, W.I. 登録日 2016-07-02 公開日 2016-12-07 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.7 Å) 主引用文献 Designed proteins induce the formation of nanocage-containing extracellular vesicles. Nature, 540, 2016
6R7H	Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome 分子名称: COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... 著者 Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. 登録日 2019-03-28 公開日 2019-08-28 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (8.8 Å) 主引用文献 Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
6R7X	CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-10, CALCIUM ION, ... 著者 Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Baronina, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2019-03-29 公開日 2019-05-01 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.47 Å) 主引用文献 The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun, 10, 2019
2LRI	NMR structure of the second PHD finger of AIRE (AIRE-PHD2) 分子名称: Autoimmune regulator, ZINC ION 著者 Gaetani, M, Chignola, F, Mollica, L, Quilici, G, Mannella, V, Spiliotopoulos, D, Musco, G. 登録日 2012-04-03 公開日 2012-10-17 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome. Nucleic Acids Res., 40, 2012
5L1N	Pyrococcus horikoshii CoA Disulfide Reductase Quadruple Mutant 分子名称: COENZYME A, Coenzyme A disulfide reductase, FLAVIN-ADENINE DINUCLEOTIDE 著者 Sea, K, Chen, B, Crane III, E.J, Sazinsky, M.H. 登録日 2016-07-29 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 A broader active site inPyrococcus horikoshiiCoA disulfide reductase accommodates larger substrates and reveals evidence of subunit asymmetry. FEBS Open Bio, 8, 2018
6QZV	DPP9 bound to a dipeptide (MP) from the N-terminus of BRCA2 分子名称: Dipeptidyl peptidase 9, MET-PRO 著者 Ross, B, Geiss-Friedlander, R, Huber, R. 登録日 2019-03-12 公開日 2020-09-30 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Dipeptidyl peptidase 9 triggers BRCA2 degradation by the N-degron pathway to promote DNA-damage repair Biorxiv, 2020
5KWI	M.tb Ag85C modified at C209 by adamantyl-ebselen 分子名称: Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ~{N}-(1-adamantyl)-2-selanyl-benzamide 著者 Goins, C.M, Ronning, D.R. 登録日 2016-07-18 公開日 2017-03-29 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives. ACS Infect Dis, 3, 2017
5L1W	X-ray Structure of 2-Mercaptoethanol modified M81C mutant of Cytochrome P450 PntM with pentalenolactone F 分子名称: PROTOPORPHYRIN IX CONTAINING FE, Pentalenolactone synthase, pentalenolactone F 著者 Duan, L, Jogl, G, Cane, D.E. 登録日 2016-07-29 公開日 2016-09-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138, 2016
2L5Q	Solution NMR Structure of BVU_3817 from Bacteroides vulgatus, Northeast Structural Genomics Consortium Target BvR159 分子名称: Uncharacterized protein 著者 Mills, J.L, Eletsky, A, Lee, H, Wang, H, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) 登録日 2010-11-03 公開日 2011-01-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Northeast Structural Genomics Consortium Target BvR159 To be Published
2LTM	Solution NMR Structure of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876B 分子名称: NFU1 iron-sulfur cluster scaffold homolog, mitochondrial 著者 Liu, G, Xiao, R, Janjua, H, Hamilton, K, Shastry, R, Kohan, E, Acton, T.B, Everett, J.K, Lee, H, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) 登録日 2012-05-29 公開日 2012-07-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876B To be Published
2L9N	Structure of the human Shwachman-Bodian-Diamond syndrome (SBDS) protein 分子名称: Ribosome maturation protein SBDS 著者 Hilcenko, C, Freund, S.M.V, Warren, A.J. 登録日 2011-02-21 公開日 2011-05-11 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome. Genes Dev., 25, 2011
6QNB	Liquid Application Method for time-resolved Analyses (LAMA) by serial synchrotron crystallography, Lysozyme with GlcNAc3 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme C 著者 Mehrabi, P, Schulz, E.C, Miller, R.J.D. 登録日 2019-02-10 公開日 2019-10-02 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Liquid application method for time-resolved analyses by serial synchrotron crystallography. Nat.Methods, 16, 2019
6QNG	Three dimensional structure of human carbonic anhydrase XII in complex with benzenesulfonamide 分子名称: Carbonic anhydrase 12, ZINC ION, ~{N}-butyl-4-chloranyl-2-(cyclohexylamino)-5-sulfamoyl-benzamide 著者 Dvinskis, E, Leitans, J, Tars, K. 登録日 2019-02-11 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Three dimensional structure of human carbonic anhydrase XII in complex with benzenesulfonamide To Be Published
6QST	Structure of CREBBP bromodomain with compound 2 bound 分子名称: CREB-binding protein, ~{N}-[3-(3-azanyl-5-methyl-1,2-oxazol-4-yl)-5-(5-ethanoyl-2-ethoxy-phenyl)phenyl]furan-2-carboxamide 著者 Zhu, J, Sledz, P, Caflisch, A. 登録日 2019-02-22 公開日 2020-03-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of CREBBP bromodomain with compound 2 bound To Be Published
5L01	Tryptophan 5-hydroxylase in complex with inhibitor (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid 分子名称: (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid, FE (III) ION, Tryptophan 5-hydroxylase 1 著者 Stein, A.J, Goldberg, D.R, De Lombaert, S, Holt, M.C. 登録日 2016-07-26 公開日 2017-01-25 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
5L08	Cryo-EM structure of Casp-8 tDED filament 分子名称: Caspase-8 著者 Fu, T.M, Li, Y, Lu, A, Wu, H. 登録日 2016-07-26 公開日 2016-11-02 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Cryo-EM Structure of Caspase-8 Tandem DED Filament Reveals Assembly and Regulation Mechanisms of the Death-Inducing Signaling Complex. Mol.Cell, 64, 2016
6QPF	Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1) 分子名称: Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit 著者 Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. 登録日 2019-02-13 公開日 2019-09-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.634 Å) 主引用文献 Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
6RAZ	D. melanogaster CMG-DNA, State 2B 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... 著者 Eickhoff, P, Martino, F, Costa, A. 登録日 2019-04-08 公開日 2019-09-18 最終更新日 2021-01-20 実験手法 ELECTRON MICROSCOPY (4.46 Å) 主引用文献 Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019

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