2LDU
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![BU of 2ldu by Molmil](/molmil-images/mine/2ldu) | Solution NMR Structure of Heat shock factor protein 1 DNA binding domain from homo sapiens, Northeast Structural Genomics Consortium Target HR3023C | 分子名称: | Heat shock factor protein 1 | 著者 | Liu, G, Xiao, R, Ciccosanti, C, Janjua, H, Acton, T.B, Lee, H, Wang, H.B, Huang, Y.B, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2011-06-01 | 公開日 | 2011-07-06 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Northeast Structural Genomics Consortium Target HR3023C To be Published
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6QU7
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![BU of 6qu7 by Molmil](/molmil-images/mine/6qu7) | Crystal structure of human DHODH in complex with BAY 2402234 | 分子名称: | ACETATE ION, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... | 著者 | Friberg, A, Gradl, S. | 登録日 | 2019-02-26 | 公開日 | 2019-06-05 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies. Leukemia, 33, 2019
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2L02
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![BU of 2l02 by Molmil](/molmil-images/mine/2l02) | Solution NMR Structure of protein BT2368 from Bacteroides thetaiotaomicron, Northeast Structural Genomics Consortium Target BtR375 | 分子名称: | Uncharacterized protein | 著者 | Eletsky, A, Lee, H, Wang, D, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-06-29 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of protein BT2368 from Bacteroides thetaiotaomicron To be Published
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6QUC
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![BU of 6quc by Molmil](/molmil-images/mine/6quc) | Truncated beta-galactosidase III from Bifidobacterium bifidum | 分子名称: | Beta-galactosidase, CALCIUM ION, IMIDAZOLE | 著者 | Thirup, S.S, Nielsen, J.A, Andersen, J.L, Alsarraf, H, Blaise, M. | 登録日 | 2019-02-27 | 公開日 | 2020-03-18 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Truncated beta-galactosidase III from Bifidobacterium bifidum To Be Published
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2LIU
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![BU of 2liu by Molmil](/molmil-images/mine/2liu) | NMR structure of holo-ACPI domain from CurA module from Lyngbya majuscula | 分子名称: | CurA | 著者 | Busche, A.E, Gottstein, D, Hein, C, Ripin, N, Pader, I, Tufar, P, Eisman, E.B, Gu, L, Walsh, C.T, Loehr, F, Sherman, D.H, Guntert, P, Dotsch, V. | 登録日 | 2011-09-01 | 公開日 | 2011-12-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Characterization of Molecular Interactions between ACP and Halogenase Domains in the Curacin A Polyketide Synthase. Acs Chem.Biol., 7, 2012
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2LKL
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![BU of 2lkl by Molmil](/molmil-images/mine/2lkl) | |
6QUT
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5KP9
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![BU of 5kp9 by Molmil](/molmil-images/mine/5kp9) | Structure of Nanoparticle Released from Enveloped Protein Nanoparticle | 分子名称: | EPN-01* | 著者 | Votteler, J, Ogohara, C, Yi, S, Hsia, Y, Natterman, U, Belnap, D.M, King, N.P, Sundquist, W.I. | 登録日 | 2016-07-02 | 公開日 | 2016-12-07 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Designed proteins induce the formation of nanocage-containing extracellular vesicles. Nature, 540, 2016
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6R7H
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![BU of 6r7h by Molmil](/molmil-images/mine/6r7h) | Structural basis of Cullin-2 RING E3 ligase regulation by the COP9 signalosome | 分子名称: | COP9 signalosome complex subunit 1, COP9 signalosome complex subunit 2, COP9 signalosome complex subunit 3, ... | 著者 | Faull, S.V, Lau, A.M.C, Beuron, F, Cronin, N.B, Morris, E.P, Politis, A. | 登録日 | 2019-03-28 | 公開日 | 2019-08-28 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (8.8 Å) | 主引用文献 | Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome. Nat Commun, 10, 2019
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6R7X
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![BU of 6r7x by Molmil](/molmil-images/mine/6r7x) | CryoEM structure of calcium-bound human TMEM16K / Anoctamin 10 in detergent (2mM Ca2+, closed form) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, Anoctamin-10, CALCIUM ION, ... | 著者 | Pike, A.C.W, Bushell, S.R, Shintre, C.A, Tessitore, A, Baronina, A, Chu, A, Mukhopadhyay, S, Shrestha, L, Chalk, R, Burgess-Brown, N.A, Love, J, Huiskonen, J.T, Edwards, A.M, Arrowsmith, C.H, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2019-03-29 | 公開日 | 2019-05-01 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | 主引用文献 | The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K. Nat Commun, 10, 2019
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2LRI
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![BU of 2lri by Molmil](/molmil-images/mine/2lri) | NMR structure of the second PHD finger of AIRE (AIRE-PHD2) | 分子名称: | Autoimmune regulator, ZINC ION | 著者 | Gaetani, M, Chignola, F, Mollica, L, Quilici, G, Mannella, V, Spiliotopoulos, D, Musco, G. | 登録日 | 2012-04-03 | 公開日 | 2012-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | AIRE-PHD fingers are structural hubs to maintain the integrity of chromatin-associated interactome. Nucleic Acids Res., 40, 2012
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5L1N
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![BU of 5l1n by Molmil](/molmil-images/mine/5l1n) | Pyrococcus horikoshii CoA Disulfide Reductase Quadruple Mutant | 分子名称: | COENZYME A, Coenzyme A disulfide reductase, FLAVIN-ADENINE DINUCLEOTIDE | 著者 | Sea, K, Chen, B, Crane III, E.J, Sazinsky, M.H. | 登録日 | 2016-07-29 | 公開日 | 2017-08-09 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | A broader active site inPyrococcus horikoshiiCoA disulfide reductase accommodates larger substrates and reveals evidence of subunit asymmetry. FEBS Open Bio, 8, 2018
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6QZV
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![BU of 6qzv by Molmil](/molmil-images/mine/6qzv) | |
5KWI
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![BU of 5kwi by Molmil](/molmil-images/mine/5kwi) | M.tb Ag85C modified at C209 by adamantyl-ebselen | 分子名称: | Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ~{N}-(1-adamantyl)-2-selanyl-benzamide | 著者 | Goins, C.M, Ronning, D.R. | 登録日 | 2016-07-18 | 公開日 | 2017-03-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives. ACS Infect Dis, 3, 2017
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5L1W
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2L5Q
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![BU of 2l5q by Molmil](/molmil-images/mine/2l5q) | Solution NMR Structure of BVU_3817 from Bacteroides vulgatus, Northeast Structural Genomics Consortium Target BvR159 | 分子名称: | Uncharacterized protein | 著者 | Mills, J.L, Eletsky, A, Lee, H, Wang, H, Ciccosanti, C, Hamilton, K, Acton, T.B, Xiao, R, Everett, J.K, Prestegard, J.H, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-11-03 | 公開日 | 2011-01-12 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Northeast Structural Genomics Consortium Target BvR159 To be Published
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2LTM
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![BU of 2ltm by Molmil](/molmil-images/mine/2ltm) | Solution NMR Structure of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876B | 分子名称: | NFU1 iron-sulfur cluster scaffold homolog, mitochondrial | 著者 | Liu, G, Xiao, R, Janjua, H, Hamilton, K, Shastry, R, Kohan, E, Acton, T.B, Everett, J.K, Lee, H, Huang, Y.J, Montelione, G.T, Northeast Structural Genomics Consortium (NESG), Mitochondrial Protein Partnership (MPP) | 登録日 | 2012-05-29 | 公開日 | 2012-07-25 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of NFU1 Iron-Sulfur Cluster Scaffold Homolog from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR2876B To be Published
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2L9N
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6QNB
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![BU of 6qnb by Molmil](/molmil-images/mine/6qnb) | |
6QNG
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![BU of 6qng by Molmil](/molmil-images/mine/6qng) | |
6QST
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5L01
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![BU of 5l01 by Molmil](/molmil-images/mine/5l01) | Tryptophan 5-hydroxylase in complex with inhibitor (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid | 分子名称: | (3~{S})-8-[2-azanyl-6-[(1~{R})-1-(4-chloranyl-2-phenyl-phenyl)-2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-2,8-diazaspiro[4.5]decane-3-carboxylic acid, FE (III) ION, Tryptophan 5-hydroxylase 1 | 著者 | Stein, A.J, Goldberg, D.R, De Lombaert, S, Holt, M.C. | 登録日 | 2016-07-26 | 公開日 | 2017-01-25 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Optimization of spirocyclic proline tryptophan hydroxylase-1 inhibitors. Bioorg. Med. Chem. Lett., 27, 2017
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5L08
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6QPF
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![BU of 6qpf by Molmil](/molmil-images/mine/6qpf) | Influenza A virus Polymerase Heterotrimer A/duck/Fujian/01/2002(H5N1) | 分子名称: | Polymerase acidic protein, Polymerase basic protein 2, RNA-directed RNA polymerase catalytic subunit | 著者 | Fan, H.T, Keown, J.R, Fodor, E, Grimes, J.M. | 登録日 | 2019-02-13 | 公開日 | 2019-09-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.634 Å) | 主引用文献 | Structures of influenza A virus RNA polymerase offer insight into viral genome replication. Nature, 573, 2019
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6RAZ
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![BU of 6raz by Molmil](/molmil-images/mine/6raz) | D. melanogaster CMG-DNA, State 2B | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, AT18545p, ... | 著者 | Eickhoff, P, Martino, F, Costa, A. | 登録日 | 2019-04-08 | 公開日 | 2019-09-18 | 最終更新日 | 2021-01-20 | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | 主引用文献 | Molecular Basis for ATP-Hydrolysis-Driven DNA Translocation by the CMG Helicase of the Eukaryotic Replisome. Cell Rep, 28, 2019
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