5KWI

M.tb Ag85C modified at C209 by adamantyl-ebselen

Summary for 5KWI

Entry DOI	10.2210/pdb5kwi/pdb
Related	5KWJ
Descriptor	Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ~{N}-(1-adamantyl)-2-selanyl-benzamide (3 entities in total)
Functional Keywords	covalent inhibitor, acyl-transferase, transferase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	33577.10
Authors	Goins, C.M.,Ronning, D.R. (deposition date: 2016-07-18, release date: 2017-03-29, Last modification date: 2023-10-04)
Primary citation	Goins, C.M.,Dajnowicz, S.,Thanna, S.,Sucheck, S.J.,Parks, J.M.,Ronning, D.R. Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives. ACS Infect Dis, 3:378-387, 2017 Cited by PubMed: 28285521 DOI: 10.1021/acsinfecdis.7b00003 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation