5L1W

X-ray Structure of 2-Mercaptoethanol modified M81C mutant of Cytochrome P450 PntM with pentalenolactone F

Summary for 5L1W

Entry DOI	10.2210/pdb5l1w/pdb
Related	5L1O 5L1P 5L1Q 5L1R 5L1S 5L1T 5L1U 5L1V
Descriptor	Pentalenolactone synthase, pentalenolactone F, PROTOPORPHYRIN IX CONTAINING FE, ... (4 entities in total)
Functional Keywords	pntm, cytochrome p450, pentalenolactone f, mutant, m81c, 2-mercaptoethanol, oxidoreductase
Biological source	Streptomyces arenae
Total number of polymer chains	1
Total formula weight	45447.66
Authors	Duan, L.,Jogl, G.,Cane, D.E. (deposition date: 2016-07-29, release date: 2016-09-14, Last modification date: 2023-10-04)
Primary citation	Duan, L.,Jogl, G.,Cane, D.E. The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism. J.Am.Chem.Soc., 138:12678-12689, 2016 Cited by PubMed: 27588339 DOI: 10.1021/jacs.6b08610 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation