8OX1
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![BU of 8ox1 by Molmil](/molmil-images/mine/8ox1) | Structure of TRF1core in complex with telomeric nucleosome | 分子名称: | Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, Histone H3.1, ... | 著者 | Hu, H, van Roon, A.M.M, Ghanim, G.E, Ahsan, B, Oluwole, A, Peak-Chew, S, Robinson, C.V, Nguyen, T.H.D. | 登録日 | 2023-04-28 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-06 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structural basis of telomeric nucleosome recognition by shelterin factor TRF1. Sci Adv, 9, 2023
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8OUE
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![BU of 8oue by Molmil](/molmil-images/mine/8oue) | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | 著者 | Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. | 登録日 | 2023-04-22 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein. Nat Commun, 15, 2024
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8OUF
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![BU of 8ouf by Molmil](/molmil-images/mine/8ouf) | The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in an open conformation | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | 著者 | Ghanim, G.E, Sekne, Z, van Roon, A.M.M, Balch, S, Nguyen, T.H.D. | 登録日 | 2023-04-22 | 公開日 | 2024-01-31 | 最終更新日 | 2024-02-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein. Nat Commun, 15, 2024
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8OJ0
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![BU of 8oj0 by Molmil](/molmil-images/mine/8oj0) | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | 登録日 | 2023-03-23 | 公開日 | 2024-02-21 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER. Nature, 627, 2024
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8QFC
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![BU of 8qfc by Molmil](/molmil-images/mine/8qfc) | UFL1 E3 ligase bound 60S ribosome | 分子名称: | 60S ribosomal protein L10a, CDK5 regulatory subunit-associated protein 3, DDRGK domain-containing protein 1, ... | 著者 | Makhlouf, L, Zeqiraj, E, Kulathu, Y. | 登録日 | 2023-09-04 | 公開日 | 2024-02-21 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons. Nature, 627, 2024
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2LY4
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![BU of 2ly4 by Molmil](/molmil-images/mine/2ly4) | HMGB1-facilitated p53 DNA binding occurs via HMG-box/p53 transactivation domain interaction and is regulated by the acidic tail | 分子名称: | Cellular tumor antigen p53, High mobility group protein B1 | 著者 | Rowell, J.P, Simpson, K.L, Stott, K, Watson, M, Thomas, J.O. | 登録日 | 2012-09-12 | 公開日 | 2012-10-31 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | HMGB1-Facilitated p53 DNA Binding Occurs via HMG-Box/p53 Transactivation Domain Interaction, Regulated by the Acidic Tail. Structure, 20, 2012
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2MU8
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![BU of 2mu8 by Molmil](/molmil-images/mine/2mu8) | Residues belonging the n-terminal region derived of merozoite surface protein-2 of plasmodium falciparum | 分子名称: | MSP-2 peptide | 著者 | Cifuentes, G, Patarroyo, M.E, Urquiza, M, Ramirez, L.E, Reyes, C, Rodriguez, R. | 登録日 | 2014-09-04 | 公開日 | 2014-11-12 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Distorting malaria peptide backbone structure to enable fitting into MHC class II molecules renders modified peptides immunogenic and protective. J.Med.Chem., 46, 2003
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2O8A
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![BU of 2o8a by Molmil](/molmil-images/mine/2o8a) | rat PP1cgamma complexed with mouse inhibitor-2 | 分子名称: | Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | 著者 | Hurley, T.D. | 登録日 | 2006-12-12 | 公開日 | 2007-07-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J.Biol.Chem., 282, 2007
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2O8G
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![BU of 2o8g by Molmil](/molmil-images/mine/2o8g) | Rat pp1c gamma complexed with mouse inhibitor-2 | 分子名称: | MANGANESE (II) ION, Protein phosphatase inhibitor 2, Serine/threonine-protein phosphatase PP1-gamma catalytic subunit | 著者 | Hurley, T.D. | 登録日 | 2006-12-12 | 公開日 | 2007-07-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J.Biol.Chem., 282, 2007
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2PLB
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![BU of 2plb by Molmil](/molmil-images/mine/2plb) | D(GTATACC) under hydrostatic pressure of 1.39 GPa | 分子名称: | 5'-D(*DGP*DGP*DTP*DAP*DTP*DAP*DCP*DC)-3', SPERMINE | 著者 | Prange, T, Girard, E, Kahn, R, Fourme, R. | 登録日 | 2007-04-19 | 公開日 | 2007-07-24 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Adaptation of the base-paired double-helix molecular architecture to extreme pressure. Nucleic Acids Res., 35, 2007
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2MWY
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![BU of 2mwy by Molmil](/molmil-images/mine/2mwy) | Mdmx-p53 | 分子名称: | Cellular tumor antigen p53, Protein Mdm4 | 著者 | Grace, C.R. | 登録日 | 2014-12-03 | 公開日 | 2016-01-27 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Monitoring Ligand-Induced Protein Ordering in Drug Discovery. J.Mol.Biol., 428, 2016
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2JQJ
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![BU of 2jqj by Molmil](/molmil-images/mine/2jqj) | NMR structure of yeast Dun1 FHA domain | 分子名称: | DNA damage response protein kinase DUN1 | 著者 | Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M. | 登録日 | 2007-06-02 | 公開日 | 2008-06-24 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Mol.Cell, 30, 2008
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2JQL
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![BU of 2jql by Molmil](/molmil-images/mine/2jql) | NMR structure of the yeast Dun1 FHA domain in complex with a doubly phosphorylated (pT) peptide derived from Rad53 SCD1 | 分子名称: | DNA damage response protein kinase DUN1, Serine/threonine-protein kinase RAD53 | 著者 | Yuan, C, Lee, H, Chang, C, Heierhorst, J, Tsai, M. | 登録日 | 2007-06-02 | 公開日 | 2008-06-24 | 最終更新日 | 2023-12-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Diphosphothreonine-specific interaction between an SQ/TQ cluster and an FHA domain in the Rad53-Dun1 kinase cascade. Mol.Cell, 30, 2008
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2K8F
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![BU of 2k8f by Molmil](/molmil-images/mine/2k8f) | Structural Basis for the Regulation of p53 Function by p300 | 分子名称: | Cellular tumor antigen p53, Histone acetyltransferase p300 | 著者 | Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E. | 登録日 | 2008-09-08 | 公開日 | 2009-03-03 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation. Structure, 17, 2009
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2HDP
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![BU of 2hdp by Molmil](/molmil-images/mine/2hdp) | Solution Structure of Hdm2 RING Finger Domain | 分子名称: | Ubiquitin-protein ligase E3 Mdm2, ZINC ION | 著者 | Kostic, M, Matt, T, Yamout-Martinez, M, Dyson, H.J, Wright, P.E. | 登録日 | 2006-06-20 | 公開日 | 2006-11-21 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the Hdm2 C2H2C4 RING, a domain critical for ubiquitination of p53. J.Mol.Biol., 363, 2006
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2L14
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![BU of 2l14 by Molmil](/molmil-images/mine/2l14) | Structure of CBP nuclear coactivator binding domain in complex with p53 TAD | 分子名称: | CREB-binding protein, Cellular tumor antigen p53 | 著者 | Lee, C, Martinez-Yamout, M.A, Dyson, H.J, Wright, P.E. | 登録日 | 2010-07-22 | 公開日 | 2010-11-03 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein. Biochemistry, 49, 2010
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2L4Z
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![BU of 2l4z by Molmil](/molmil-images/mine/2l4z) | NMR structure of fusion of CtIP (641-685) to LMO4-LIM1 (18-82) | 分子名称: | DNA endonuclease RBBP8,LIM domain transcription factor LMO4, ZINC ION | 著者 | Liew, C, Stokes, P.H, Kwan, A.H, Matthews, J.M. | 登録日 | 2010-10-22 | 公開日 | 2011-10-26 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis of the Interaction of the Breast Cancer Oncogene LMO4 with the Tumour Suppressor CtIP/RBBP8. J.Mol.Biol., 425, 2013
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2JQI
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2LEF
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![BU of 2lef by Molmil](/molmil-images/mine/2lef) | LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES | 分子名称: | DNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR) | 著者 | Li, X, Love, J.J, Case, D.A, Wright, P.E. | 登録日 | 1998-10-13 | 公開日 | 1998-10-21 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature, 376, 1995
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2LJ9
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2LJL
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2L9Q
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2U2A
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2WTJ
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![BU of 2wtj by Molmil](/molmil-images/mine/2wtj) | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE, CHECKPOINT KINASE 2, ... | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | 登録日 | 2009-09-16 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2 Bioorg.Med.Chem., 18, 2010
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2WTI
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![BU of 2wti by Molmil](/molmil-images/mine/2wti) | CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR | 分子名称: | 1,2-ETHANEDIOL, 4-[2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)PYRIDIN-3-YL]BENZAMIDE, CHECKPOINT KINASE 2, ... | 著者 | Hilton, S, Naud, S, Caldwell, J.J, Boxall, K, Burns, S, Anderson, V.E, Antoni, L, Allen, C.E, Pearl, L.H, Oliver, A.W, Aherne, G.W, Garrett, M.D, Collins, I. | 登録日 | 2009-09-16 | 公開日 | 2009-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Identification and Characterisation of 2-Aminopyridine Inhibitors of Checkpoint Kinase 2 Bioorg.Med.Chem., 18, 2010
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