2LEF

LEF1 HMG DOMAIN (FROM MOUSE), COMPLEXED WITH DNA (15BP), NMR, 12 STRUCTURES

Replaces:  1LEF

Summary for 2LEF

DescriptorDNA (5'-D(*CP*AP*CP*CP*CP*TP*TP*TP*GP*AP*AP*GP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*CP*TP*TP*CP*AP*AP*AP*GP*GP*GP*TP*G)-3'), PROTEIN (LYMPHOID ENHANCER-BINDING FACTOR) (3 entities in total)
Functional Keywordslef1, hmg, tcr-a, transcription factor, dna binding, dna bending, complex (hmg domain-dna), gene regulation-dna complex, gene regulation/dna
Biological sourceMus musculus (house mouse)
Cellular locationNucleus P27782
Total number of polymer chains3
Total molecular weight19582.2
Authors
Li, X.,Love, J.J.,Case, D.A.,Wright, P.E. (deposition date: 1998-10-13, release date: 1998-10-21, Last modification date: 2011-07-13)
Primary citation
Love, J.J.,Li, X.,Case, D.A.,Giese, K.,Grosschedl, R.,Wright, P.E.
Structural basis for DNA bending by the architectural transcription factor LEF-1.
Nature, 376:791-795, 1995
PubMed: 7651541 (PDB entries with the same primary citation)
DOI: 10.1038/376791a0
MImport into Mendeley
Experimental method
SOLUTION NMR
NMR Information
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Structure validation

ClashscoreRamachandran outliersSidechain outliers01.2%5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures

More Asymmetric unit images

Molmil generated image of 2lef
no rotation
Molmil generated image of 2lef
rotated about x axis by 90°
Molmil generated image of 2lef
rotated about y axis by 90°