8OUE

The H/ACA RNP lobe of human telomerase with the dyskerin thumb loop in a semi-closed conformation

This is a non-PDB format compatible entry.

Summary for 8OUE

• Entry DOI: 10.2210/pdb8oue/pdb
• Related: 8OUF
• EMDB information: 17190
• Descriptor: H/ACA ribonucleoprotein complex subunit DKC1, H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, ... (6 entities in total)
• Functional Keywords: telomerase, h/aca, pseudouridylation, ribonucleoprotein, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 415061.33

Authors

Ghanim, G.E.,Sekne, Z.,van Roon, A.M.M.,Balch, S.,Nguyen, T.H.D. (deposition date: 2023-04-22, release date: 2024-01-31, Last modification date: 2024-02-07)

• Primary citation: Ghanim, G.E.,Sekne, Z.,Balch, S.,van Roon, A.M.,Nguyen, T.H.D.; 2.7 angstrom cryo-EM structure of human telomerase H/ACA ribonucleoprotein.; Nat Commun, 15:746-746, 2024; PubMed: 38272871; DOI: 10.1038/s41467-024-45002-x

Experimental method

ELECTRON MICROSCOPY (2.7 Å)