PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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3OS5	SET7/9-Dnmt1 K142me1 complex 分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dnmt1, ... 著者 Esteve, P.-O, Chang, Y, Samaranayake, M, Upadhyay, A.K, Horton, J.R, Feehery, G.R, Cheng, X, Pradhan, S. 登録日 2010-09-08 公開日 2010-12-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability. Nat.Struct.Mol.Biol., 18, 2011
1TFI	A NOVEL ZN FINGER MOTIF IN THE BASAL TRANSCRIPTIONAL MACHINERY: THREE-DIMENSIONAL NMR STUDIES OF THE NUCLEIC-ACID BINDING DOMAIN OF TRANSCRIPTIONAL ELONGATION FACTOR TFIIS 分子名称: TRANSCRIPTIONAL ELONGATION FACTOR SII, ZINC ION 著者 Qian, X, Gozani, S, Yoon, H.S, Jeon, C.J, Agarwal, K, Weiss, M.A. 登録日 1993-04-27 公開日 1993-10-31 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Novel zinc finger motif in the basal transcriptional machinery: three-dimensional NMR studies of the nucleic acid binding domain of transcriptional elongation factor TFIIS. Biochemistry, 32, 1993
2H4R	Crystal structure of wildtype MENT in the native conformation 分子名称: Heterochromatin-associated protein MENT 著者 Irving, J.A, Whisstock, J.C, Buckle, A.M, McGowan, S. 登録日 2006-05-25 公開日 2006-07-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 X-ray crystal structure of MENT: evidence for functional loop-sheet polymers in chromatin condensation. Embo J., 25, 2006
3PF4	Crystal structure of Bs-CspB in complex with r(GUCUUUA) 分子名称: Cold shock protein cspB, MAGNESIUM ION, SODIUM ION, ... 著者 Sachs, R, Max, K.E.A, Heinemann, U. 登録日 2010-10-27 公開日 2011-09-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution. Rna, 18, 2012
3PF5	Crystal structure of Bs-CspB in complex with rU6 分子名称: Cold shock protein cspB, MAGNESIUM ION, hexaribouracil (rU6) 著者 Sachs, R, Max, K.E.A, Heinemann, U. 登録日 2010-10-27 公開日 2011-09-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 RNA single strands bind to a conserved surface of the major cold shock protein in crystals and solution. Rna, 18, 2012
2L9S	Solution structure of Pf1 SID1-mSin3A PAH2 Complex 分子名称: PHD finger protein 12, Paired amphipathic helix protein Sin3a 著者 Senthil Kumar, G, Xie, T, Zhang, Y, Radhakrishnan, I. 登録日 2011-02-23 公開日 2011-05-11 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the mSin3A PAH2-Pf1 SID1 Complex: A Mad1/Mxd1-Like Interaction Disrupted by MRG15 in the Rpd3S/Sin3S Complex. J.Mol.Biol., 408, 2011
5H93	Crystal structure of Geobacter metallireducens SMUG1 分子名称: Geobacter metallireducens SMUG1 著者 Xie, W, Cao, W, Zhang, Z, Shen, J. 登録日 2015-12-25 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.176 Å) 主引用文献 Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1 Acs Chem.Biol., 11, 2016
5H98	Crystal structure of Geobacter metallireducens SMUG1 分子名称: Geobacter metallireducens SMUG1 著者 Xie, W, Cao, W, Zhang, Z, Shen, J. 登録日 2015-12-26 公開日 2016-04-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural Basis of Substrate Specificity in Geobacter metallireducens SMUG1 Acs Chem.Biol., 11, 2016
5LPG	Structure of NUDT15 in complex with 6-thio-GMP 分子名称: MAGNESIUM ION, Probable 8-oxo-dGTP diphosphatase NUDT15, [(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-6-sulfanyl-purin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate 著者 Masuyer, G, Carter, M, Rehling, D, Stenmark, P, Helleday, T, Jemth, A.-S, Valerie, N.C.K, Homan, E, Herr, P, Bevc, L, Page, B.D.G, Hagenkort, A. 登録日 2016-08-12 公開日 2016-08-24 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine. Cancer Res., 76, 2016
5LUS	Structures of DHBN domain of Pelecanus crispus BLM helicase 分子名称: BLM helicase 著者 Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. 登録日 2016-09-09 公開日 2017-03-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.433 Å) 主引用文献 A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
5LUT	Structures of DHBN domain of Gallus gallus BLM helicase 分子名称: BLM helicase, PHOSPHATE ION 著者 Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G. 登録日 2016-09-09 公開日 2017-03-01 最終更新日 2017-04-19 実験手法 X-RAY DIFFRACTION (2.72 Å) 主引用文献 A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation. J. Biol. Chem., 292, 2017
3HP9	Crystal structure of SSB/Exonuclease I in complex with inhibitor CFAM 分子名称: 1,2-ETHANEDIOL, 2-{[2-chloro-5-(trifluoromethyl)phenyl]amino}-5-methoxybenzoic acid, DIMETHYL SULFOXIDE, ... 著者 Satyshur, K.A. 登録日 2009-06-03 公開日 2010-01-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Small-molecule tools for dissecting the roles of SSB/protein interactions in genome maintenance Proc.Natl.Acad.Sci.USA, 107, 2010
6YES	Crystal structure of type I-D CRISPR-Cas nuclease Cas10d 分子名称: CRISPR-associated protein, CscA, ZINC ION 著者 Brodersen, D.E, Van, L.B, Manav, M.C. 登録日 2020-03-25 公開日 2020-10-28 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein. Nat Commun, 11, 2020
1B9F	MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY 分子名称: CACODYLATE ION, PROTEIN (INTEGRASE), SULFATE ION 著者 Greenwald, J, Le, V, Butler, S.L, Bushman, F.D, Choe, S. 登録日 1999-02-11 公開日 1999-07-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity. Biochemistry, 38, 1999
1B92	MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY 分子名称: CACODYLATE ION, PROTEIN (INTEGRASE), SULFATE ION 著者 Greenwald, J, Le, V, Butler, S.L, Bushman, F.D, Choe, S. 登録日 1999-02-19 公開日 1999-07-19 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity. Biochemistry, 38, 1999
1B9D	MOBILITY OF AN HIV-1 INTEGRASE ACTIVE SITE LOOP IS CORRELATED WITH CATALYTIC ACTIVITY 分子名称: CACODYLATE ION, PROTEIN (INTEGRASE), SULFATE ION 著者 Greenwald, J, Le, V, Butler, S.L, Bushman, F.D, Choe, S. 登録日 1999-02-11 公開日 1999-07-19 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity. Biochemistry, 38, 1999
3O4N	Crystal structure of the Rous Associated Virus Integrase catalytic domain in MES buffer pH 6.0 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ZINC ION, integrase 著者 Ballandras, A, Robert, X, Gouet, P. 登録日 2010-07-27 公開日 2011-08-31 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly. Plos One, 6, 2011
7YPE	Crystal structure of AsfvPCNA in space group of P63 分子名称: E301R, GLYCEROL 著者 Shao, Z.W, Gan, J.H. 登録日 2022-08-03 公開日 2023-07-26 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional studies of PCNA from African swine fever virus. J.Virol., 97, 2023
7YPF	Crystal structure of AsfvPCNA in space group of P1 分子名称: E301R 著者 Shao, Z.W, Gan, J.H. 登録日 2022-08-03 公開日 2023-08-02 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and functional studies of PCNA from African swine fever virus. J.Virol., 97, 2023
3O4Q	Crystal structure of the Rous Associated Virus Integrase catalytic domain A182T in citrate buffer pH 6.2 分子名称: CITRATE ANION, integrase 著者 Ballandras, A, Robert, X, Gouet, P. 登録日 2010-07-27 公開日 2011-08-31 最終更新日 2021-10-06 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly. Plos One, 6, 2011
3O4Z	Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes 分子名称: Telomere length regulation protein TEL2 著者 Xie, Y, Pavletich, N.P. 登録日 2010-07-27 公開日 2010-09-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes. Genes Dev., 24, 2010
5M8C	Spliceosome component 分子名称: Pre-mRNA-processing factor 19 著者 Moura, T.R, Pena, V. 登録日 2016-10-28 公開日 2018-02-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Prp19/Pso4 Is an Autoinhibited Ubiquitin Ligase Activated by Stepwise Assembly of Three Splicing Factors. Mol. Cell, 69, 2018
6STI	Crystal structure of RXRalpha LBD in complex with LG 100754 and a coactivator peptide 分子名称: (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid, ACETATE ION, Nuclear receptor coactivator 2, ... 著者 le Maire, A, Teyssier, C, Germain, P, Bourguet, W. 登録日 2019-09-10 公開日 2019-11-20 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.892 Å) 主引用文献 Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations. Cells, 8, 2019
5J4H	Structure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acid 分子名称: 1H-indole-6-carboxylic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. 登録日 2016-04-01 公開日 2016-10-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.374 Å) 主引用文献 Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
8D3M	Type I-C Cas4-Cas1-Cas2 complex bound to a PAM/Processed prespacer 分子名称: CRISPR-associated endonuclease Cas1, CRISPR-associated endonuclease Cas2, CRISPR-associated exonuclease Cas4, ... 著者 Dhingra, Y, Suresh, S.K, Juneja, P, Sashital, D.G. 登録日 2022-06-01 公開日 2022-11-02 最終更新日 2022-11-30 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 PAM binding ensures orientational integration during Cas4-Cas1-Cas2-mediated CRISPR adaptation. Mol.Cell, 82, 2022

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