6STI

Crystal structure of RXRalpha LBD in complex with LG 100754 and a coactivator peptide

Summary for 6STI

Entry DOI	10.2210/pdb6sti/pdb
Descriptor	Retinoic acid receptor RXR-alpha, Nuclear receptor coactivator 2, (2E,4E,6Z)-3-methyl-7-(5,5,8,8-tetramethyl-3-propoxy-5,6,7,8-tetrahydronaphthalen-2-yl)octa-2,4,6-trienoic acid, ... (5 entities in total)
Functional Keywords	nuclear receptor, ligand binding, transcription
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	29304.99
Authors	le Maire, A.,Teyssier, C.,Germain, P.,Bourguet, W. (deposition date: 2019-09-10, release date: 2019-11-20, Last modification date: 2024-01-31)
Primary citation	le Maire, A.,Teyssier, C.,Balaguer, P.,Bourguet, W.,Germain, P. Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations. Cells, 8:-, 2019 Cited by PubMed: 31694317 DOI: 10.3390/cells8111392 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.892 Å)

Structure validation