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8W3V
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Crystal structure of human WDR41
分子名称: WD repeat-containing protein 41
著者Hutchinson, A, Dong, A, Li, Y, Seitova, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2024-02-22
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of human WDR41
To be published
8W3A
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Crystal structure of Shewanella benthica Group 1 truncated hemoglobin C51S C71S variant with trans heme D
分子名称: Group 1 truncated hemoglobin, PROTOPORPHYRIN IX CONTAINING FE, {3-[(2R,5'R)-9',14'-diethenyl-5'-hydroxy-5',10',15',19'-tetramethyl-5-oxo-4,5-dihydro-3H-spiro[furan-2,4'-[21,22,23,24]tetraazapentacyclo[16.2.1.13,6.18,11.113,16]tetracosa[1,3(24),6,8,10,12,14,16(22),17,19]decaen]-20'-yl-kappa~4~N~21'~,N~22'~,N~23'~,N~24'~]propanoato}iron
著者Lecomte, J.T.J, Schlessman, J.L, Schultz, T.D, Siegler, M.A.
登録日2024-02-22
公開日2024-04-03
最終更新日2024-07-17
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Heme d formation in a Shewanella benthica hemoglobin.
J.Inorg.Biochem., 259, 2024
8W34
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HIV-1 intasome core assembled with wild-type integrase, 1F
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*AP*C)-3'), DNA (5'-D(P*GP*TP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3'), ...
著者Li, M, Craigie, R.
登録日2024-02-21
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro.
J.Mol.Biol., 436, 2024
8W33
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Structure of McrD (methyl-coenzyme M reductase operon protein D) from Methanomassiliicoccus luminyensis
分子名称: GLYCEROL, McrD (methyl-coenzyme M reductase operon protein D)
著者Sutherland-Smith, A.J, Carbone, V, Schofield, L.R, Ronimus, R.S.
登録日2024-02-21
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The crystal structure of methanogen McrD, a methyl-coenzyme M reductase-associated protein.
Febs Open Bio, 2024
8W2W
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Structure of transthyretin synthetic mutation A120L
分子名称: Transthyretin
著者Yang, K, Sun, X, Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-21
公開日2024-02-28
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
8W2R
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HIV-1 P5-IN intasome core
分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (5'-D(*AP*CP*TP*GP*CP*TP*AP*GP*AP*GP*AP*TP*TP*TP*TP*CP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*GP*AP*AP*AP*AP*TP*CP*TP*CP*TP*AP*GP*CP*A)-3'), ...
著者Li, M, Craigie, R.
登録日2024-02-21
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献HIV-1 Integrase Assembles Multiple Species of Stable Synaptic Complex Intasomes That Are Active for Concerted DNA Integration In vitro.
J.Mol.Biol., 436, 2024
8W2O
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Yeast U1 snRNP with humanized U1C Zinc-Finger domain
分子名称: 56 kDa U1 small nuclear ribonucleoprotein component, ACT1 pre-mRNA, Pre-mRNA-processing factor 39, ...
著者Shi, S.S, Kuang, Z.L, Zhao, R.
登録日2024-02-20
公開日2024-05-15
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast.
Rna, 2024
8W2L
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TRPM7 structure in complex with anticancer agent CCT128930 in closed state
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-[2-[(1~{S},2~{S},4~{S},5'~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2'-oxane]-16-yl]oxyethyl]propane-1,3-diol, 4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-aminium, ...
著者Nadezhdin, K.D, Sobolevsky, A.I.
登録日2024-02-20
公開日2024-04-17
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Structural basis of selective TRPM7 inhibition by the anticancer agent CCT128930.
Cell Rep, 43, 2024
8W26
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X-ray crystal structure of the GAF-PHY domains of SyB-Cph1
分子名称: 1,2-ETHANEDIOL, ACETATE ION, PHYCOCYANOBILIN, ...
著者Burgie, E.S, Vierstra, R.D.
登録日2024-02-20
公開日2024-05-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of the Photosensory Module from a PAS-Less Cyanobacterial Phytochrome Reveals a Hybrid Activated Conformation in the Dark-Adapted Pr State
To Be Published
8W22
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Umb1 umbrella toxin particle (local refinement of UmbB1 bound ALF of UmbC1 and UmbA1)
分子名称: Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein
著者Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D.
登録日2024-02-19
公開日2024-04-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Streptomyces umbrella toxin particles block hyphal growth of competing species.
Nature, 629, 2024
8W21
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Crystal Structure of Enolase from Chlamydia trachomatis (P43212 Form)
分子名称: DI(HYDROXYETHYL)ETHER, Enolase, GLYCEROL, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2024-02-19
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Enolase from Chlamydia trachomatis (P43212 Form)
To be published
8W20
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Umb1 umbrella toxin particle
分子名称: Intein C-terminal splicing domain-containing protein, Secreted esterase, Secreted protein
著者Park, Y.J, Zhao, Q, Seattle Structural Genomics Center for Infectious Disease (SSGCID), DiMaio, F, Mougous, J.D, Veesler, D.
登録日2024-02-19
公開日2024-04-17
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Streptomyces umbrella toxin particles block hyphal growth of competing species.
Nature, 629, 2024
8W1V
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The beta2 adrenergic receptor bound to a bitopic ligand
分子名称: (2S)-1-[(3-{1-[4-(4-{(2S)-2-hydroxy-3-[(propan-2-yl)amino]propoxy}phenyl)butyl]-1H-1,2,3-triazol-4-yl}propyl)amino]-3-(2-propylphenoxy)propan-2-ol, Beta-2 adrenergic receptor,Endolysin, Lauryl Maltose Neopentyl Glycol, ...
著者Gaiser, B, Danielsen, M, Xu, X, Jorgensen, K, Fronik, P, Marcher-Rorsted, E, Wrobe, T, Hirata, K, Liu, X, Mathiesen, J, Pedersen, D.
登録日2024-02-19
公開日2024-07-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Bitopic Ligands Support the Presence of a Metastable Binding Site at the beta 2 Adrenergic Receptor.
J.Med.Chem., 2024
8W1S
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Cryo-EM structure of BTV pre-core
分子名称: Core protein VP3, RNA-directed RNA polymerase
著者Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
登録日2024-02-17
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W1R
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Cryo-EM structure of BTV core
分子名称: Core protein VP3, RNA-directed RNA polymerase
著者Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
登録日2024-02-17
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W1O
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Cryo-EM structure of BTV virion
分子名称: Core protein VP3, Outer capsid protein VP2, RNA-1, ...
著者Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
登録日2024-02-16
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W1N
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Structure of transthyretin pathogenic mutation A120S
分子名称: Transthyretin
著者Ferguson, J.A, Stanfield, R.L, Wright, P.E.
登録日2024-02-16
公開日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin
To Be Published
8W1L
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Structure of CSF1R kinase domain in complex with Cpd 32
分子名称: GLYCEROL, Macrophage colony-stimulating factor 1 receptor,CSF1R, SULFATE ION, ...
著者Kothe, M, Chodaparambil, J.
登録日2024-02-16
公開日2024-05-29
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Identification of Selective Imidazopyridine CSF1R Inhibitors.
Acs Med.Chem.Lett., 15, 2024
8W1I
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Cryo-EM structure of BTV subcore
分子名称: Core protein VP3
著者Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
登録日2024-02-16
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W1F
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Crystal Structure of DPS-like protein PA4880 from Pseudomonas aeruginosa (dodecamer, Mg bound)
分子名称: DPS-LIKE PROTEIN, FE (II) ION, MAGNESIUM ION, ...
著者Lovell, S, Liu, L, Seibold, S, Battaile, K.P, Rivera, M.
登録日2024-02-15
公開日2024-05-29
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
8W1E
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Crystal Structure of DPS-like protein PA4880 from Pseudomonas aeruginosa (dodecamer)
分子名称: DPS-LIKE PROTEIN, FE (II) ION, SULFATE ION
著者Lovell, S, Liu, L, Seibold, S, Battaile, K.P, Rivera, M.
登録日2024-02-15
公開日2024-05-29
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
8W1D
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CRYSTAL STRUCTURE OF DPS-LIKE PROTEIN PA4880 FROM PSEUDOMONAS AERUGINOSA (DIMERIC FORM)
分子名称: DPS-LIKE PROTEIN, FE (II) ION
著者Lovell, S, Battaile, K.P, Rivera, M.
登録日2024-02-15
公開日2024-05-29
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Pseudomonas aeruginosa gene PA4880 encodes a Dps-like protein with a Dps fold, bacterioferritin-type ferroxidase centers, and endonuclease activity.
Front Mol Biosci, 11, 2024
8W1C
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Cryo-EM structure of BTV pre-subcore
分子名称: Core protein VP3, VP6
著者Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
登録日2024-02-15
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W19
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Cryo-EM structure of BTV star-subcore
分子名称: Core protein VP3, VP6
著者Xia, X, Sung, P.Y, Martynowycz, M.W, Gonen, T, Roy, P, Zhou, Z.H.
登録日2024-02-15
公開日2024-04-24
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献RNA genome packaging and capsid assembly of bluetongue virus visualized in host cells.
Cell, 187, 2024
8W18
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The crystal structure of the Michaelis-Menten complex of a C1s/C1-INH at 3.94 Angstroms
分子名称: Complement C1s subcomponent heavy chain, Complement C1s subcomponent light chain, Plasma protease C1 inhibitor
著者Garrigues, R.J, Garcia, B.L.
登録日2024-02-15
公開日2024-06-26
実験手法X-RAY DIFFRACTION (3.94 Å)
主引用文献The crystal structure of the Michaelis-Menten complex of a C1s/C1-INH
To Be Published

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件を2024-07-17に公開中

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