8W1N

Structure of transthyretin pathogenic mutation A120S

Summary for 8W1N

• Entry DOI: 10.2210/pdb8w1n/pdb
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: tetramer, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 27849.11

Authors

Ferguson, J.A.,Stanfield, R.L.,Wright, P.E. (deposition date: 2024-02-16, release date: 2024-02-28)

• Primary citation: Sun, X.,Ferguson, J.A.,Yang, K.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E.; The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)