8W1N
Structure of transthyretin pathogenic mutation A120S
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transthyretin | polymer | 128 | 13924.6 | 2 | UniProt (P02766) Pfam (PF00576) | Homo sapiens (human) | ATTR,Prealbumin,TBPA |
| 2 | C, D (A, B) | water | water | 18.0 | 218 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 127 (UniProt: P02766)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Ser 120 | Ala 140 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27849.1 | |
| All* | Total formula weight | 27849.1 |
