8W2W

Structure of transthyretin synthetic mutation A120L

Summary for 8W2W

• Entry DOI: 10.2210/pdb8w2w/pdb
• Descriptor: Transthyretin (2 entities in total)
• Functional Keywords: tetramer, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 15947.06

Authors

Yang, K.,Sun, X.,Ferguson, J.A.,Stanfield, R.L.,Wright, P.E. (deposition date: 2024-02-21, release date: 2024-02-28)

• Primary citation: Sun, X.,Ferguson, J.A.,Yang, K.,Stanfield, R.L.,Dyson, H.J.,Wright, P.E.; The mispacked F87 sidechain drives aggregation-promoting conformational fluctuations in transthyretin; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.07 Å)