8W2O

Yeast U1 snRNP with humanized U1C Zinc-Finger domain

Summary for 8W2O

• Entry DOI: 10.2210/pdb8w2o/pdb
• EMDB information: 43753
• Descriptor: U1 small nuclear ribonucleoprotein 70 kDa homolog, Small nuclear ribonucleoprotein-associated protein B, Small nuclear ribonucleoprotein Sm D1, ... (18 entities in total)
• Functional Keywords: u1snrnp, u1c humanization, splicing
• Biological source: Saccharomyces cerevisiae S288C; More
• Total number of polymer chains: 18
• Total formula weight: 725147.13

Authors

Shi, S.S.,Kuang, Z.L.,Zhao, R. (deposition date: 2024-02-20, release date: 2024-05-15)

• Primary citation: Chalivendra, S.,Shi, S.,Li, X.,Kuang, Z.,Giovinazzo, J.,Zhang, L.,Rossi, J.,Wang, J.,Saviola, A.,Welty, R.,Liu, S.,Vaeth, K.,Zhou, Z.H.,Hansen, K.,Taliaferro, J.M.,Zhao, R.; Selected humanization of yeast U1 snRNP leads to global suppression of pre-mRNA splicing and mitochondrial dysfunction in the budding yeast.; Rna, 2024; PubMed: 38688558; DOI: 10.1261/rna.079917.123

Experimental method

ELECTRON MICROSCOPY (3.49 Å)