3ULR
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![BU of 3ulr by Molmil](/molmil-images/mine/3ulr) | Lysozyme contamination facilitates crystallization of a hetero-trimericCortactin:Arg:Lysozyme complex | 分子名称: | Abelson tyrosine-protein kinase 2, Lysozyme C, Src substrate cortactin | 著者 | Liu, W, MacGrath, S, Koleske, A.J, Boggon, T.J. | 登録日 | 2011-11-11 | 公開日 | 2012-01-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Lysozyme contamination facilitates crystallization of a heterotrimeric cortactin-Arg-lysozyme complex. Acta Crystallogr.,Sect.F, 68, 2012
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3UMS
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![BU of 3ums by Molmil](/molmil-images/mine/3ums) | Crystal structure of the G202A mutant of human G-alpha-i1 | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, Guanine nucleotide-binding protein G(i) subunit alpha-1, ... | 著者 | Lambert, N.A, Johnston, C.A, Cappell, S.D, Kuravi, S, Kimple, A.J, Willard, F.S, Siderovski, D.P. | 登録日 | 2011-11-14 | 公開日 | 2012-02-08 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.343 Å) | 主引用文献 | Correction for Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity Proc.Natl.Acad.Sci.USA, 2012
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4OOP
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![BU of 4oop by Molmil](/molmil-images/mine/4oop) | Arabidopsis thaliana dUTPase with with magnesium and alpha,beta-imido-dUTP | 分子名称: | 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, Deoxyuridine 5'-triphosphate nucleotidohydrolase, MAGNESIUM ION | 著者 | Inoguchi, N, Bajaj, M, Moriyama, H. | 登録日 | 2014-02-03 | 公開日 | 2015-04-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural insights into the mechanism defining substrate affinity in Arabidopsis thaliana dUTPase: the role of tryptophan 93 in ligand orientation. BMC Res Notes, 8, 2015
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4O74
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![BU of 4o74 by Molmil](/molmil-images/mine/4o74) | Crystal structure of the first bromodomain of human BRD4 in complex with BI 2536 | 分子名称: | 1,2-ETHANEDIOL, 4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide, Bromodomain-containing protein 4, ... | 著者 | Ember, S.W, Zhu, J.-Y, Watts, C, Schonbrunn, E. | 登録日 | 2013-12-24 | 公開日 | 2014-03-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Acetyl-lysine Binding Site of Bromodomain-Containing Protein 4 (BRD4) Interacts with Diverse Kinase Inhibitors. Acs Chem.Biol., 9, 2014
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3ULY
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3UNE
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![BU of 3une by Molmil](/molmil-images/mine/3une) | Mouse constitutive 20S proteasome | 分子名称: | Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, Proteasome subunit alpha type-3, ... | 著者 | Huber, E, Basler, M, Schwab, R, Heinemeyer, W, Kirk, C, Groettrup, M, Groll, M. | 登録日 | 2011-11-15 | 公開日 | 2012-02-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Immuno- and constitutive proteasome crystal structures reveal differences in substrate and inhibitor specificity. Cell(Cambridge,Mass.), 148, 2012
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4O7H
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![BU of 4o7h by Molmil](/molmil-images/mine/4o7h) | Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460 | 分子名称: | Glutathione S-transferase | 著者 | Kim, J, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Stead, M, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Attonito, J.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | 登録日 | 2013-12-24 | 公開日 | 2014-01-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of a glutathione S-transferase from Rhodospirillum rubrum F11, Target EFI-507460 TO BE PUBLISHED
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3UMN
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![BU of 3umn by Molmil](/molmil-images/mine/3umn) | Crystal Structure of Lamin-B1 | 分子名称: | Lamin-B1 | 著者 | Xu, C, Bian, C.B, Amaya, M.F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC) | 登録日 | 2011-11-14 | 公開日 | 2011-11-30 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1. Febs Lett., 586, 2012
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4OP8
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![BU of 4op8 by Molmil](/molmil-images/mine/4op8) | Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation | 分子名称: | CALCIUM ION, SULFATE ION, TEM-94 ES-beta-lactamase, ... | 著者 | Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. | 登録日 | 2014-02-05 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
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3USG
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![BU of 3usg by Molmil](/molmil-images/mine/3usg) | Crystal structure of LeuT bound to L-leucine in space group C2 from lipid bicelles | 分子名称: | ACETATE ION, DI(HYDROXYETHYL)ETHER, LEUCINE, ... | 著者 | Wang, H, Elferich, J, Gouaux, E. | 登録日 | 2011-11-23 | 公開日 | 2012-01-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.502 Å) | 主引用文献 | Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
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3UMR
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![BU of 3umr by Molmil](/molmil-images/mine/3umr) | Crystal structure of the G202D mutant of human G-alpha-i1 | 分子名称: | CHLORIDE ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Johnston, C.A, Afshar, K, Snyder, J.T, Tall, G.G, Gonczy, P, Siderovski, D.P, Willard, F.S. | 登録日 | 2011-11-14 | 公開日 | 2012-10-24 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Structural Determinants Underlying the Temperature-sensitive Nature of a G-alpha Mutant in Asymmetric Cell Division of Caenorhabditis elegans To be Published
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3USQ
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![BU of 3usq by Molmil](/molmil-images/mine/3usq) | Structure of D159S/Y194F glycogenin mutant truncated at residue 270 | 分子名称: | CHLORIDE ION, GLYCEROL, Glycogenin-1 | 著者 | Issoglio, F.M, Carrizo, M.E, Romero, J.M, Curtino, J.A. | 登録日 | 2011-11-23 | 公開日 | 2011-12-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mechanisms of monomeric and dimeric glycogenin autoglucosylation. J.Biol.Chem., 287, 2012
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4O87
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![BU of 4o87 by Molmil](/molmil-images/mine/4o87) | Crystal structure of a N-tagged Nuclease | 分子名称: | CITRIC ACID, N-tagged Nuclease, SULFATE ION | 著者 | Chakravarty, A.K, Smith, P, Shuman, S. | 登録日 | 2013-12-26 | 公開日 | 2014-10-15 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure, mechanism, and specificity of a eukaryal tRNA restriction enzyme involved in self-nonself discrimination. Cell Rep, 7, 2014
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3USV
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2QUW
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![BU of 2quw by Molmil](/molmil-images/mine/2quw) | |
4O8V
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![BU of 4o8v by Molmil](/molmil-images/mine/4o8v) | O-Acetyltransferase Domain of Pseudomonas putida AlgJ | 分子名称: | Alginate biosynthesis protein AlgJ | 著者 | Ricer, T, Little, D.J, Whitney, J.C, Robinson, H, Howell, P.L. | 登録日 | 2013-12-30 | 公開日 | 2014-10-01 | 実験手法 | X-RAY DIFFRACTION (1.815 Å) | 主引用文献 | P. aeruginosa SGNH Hydrolase-Like Proteins AlgJ and AlgX Have Similar Topology but Separate and Distinct Roles in Alginate Acetylation. Plos Pathog., 10, 2014
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4OPQ
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![BU of 4opq by Molmil](/molmil-images/mine/4opq) | Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying R164S/G238S mutations | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, SULFATE ION, ... | 著者 | Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. | 登録日 | 2014-02-06 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
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3UTD
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![BU of 3utd by Molmil](/molmil-images/mine/3utd) | Ec_IspH in complex with 4-oxopentyl diphosphate | 分子名称: | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, 4-oxopentyl trihydrogen diphosphate, FE3-S4 CLUSTER | 著者 | Span, I, Wang, K, Wang, W, Zhang, Y, Bacher, A, Eisenreich, W, Schulz, C, Oldfield, E, Groll, M. | 登録日 | 2011-11-25 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. Nat Commun, 3, 2012
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4OPZ
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![BU of 4opz by Molmil](/molmil-images/mine/4opz) | Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation in complex with boron-based inhibitor EC25 | 分子名称: | 1,2-ETHANEDIOL, 3-[(2R)-2-{[(2R)-2-amino-2-phenylacetyl]amino}-2-(dihydroxyboranyl)ethyl]benzoic acid, ACETATE ION, ... | 著者 | Dellus-Gur, E, Elias, M, Fraser, J.S, Tawfik, D.S. | 登録日 | 2014-02-07 | 公開日 | 2015-05-20 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427, 2015
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4OAE
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![BU of 4oae by Molmil](/molmil-images/mine/4oae) | Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol | 分子名称: | 1,2-ETHANEDIOL, CHLORAMPHENICOL, GNAT superfamily acetyltransferase PA4794, ... | 著者 | Majorek, K.A, Chruszcz, M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2014-01-04 | 公開日 | 2014-01-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Crystal structure of a GNAT superfamily acetyltransferase PA4794 C29A/C117A/Y128A mutant in complex with chloramphenicol To be Published
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3UTZ
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![BU of 3utz by Molmil](/molmil-images/mine/3utz) | Endogenous-like inhibitory antibodies targeting activated metalloproteinase motifs show therapeutic potential | 分子名称: | Metalloproteinase, heavy chain, light chain, ... | 著者 | Sela-Passwell, N, Kikkeri, R, Dym, O, Rozenberg, H, Margalit, R, Arad-Yellin, R, Eisenstein, M, Brenner, O, Shoham, T, Danon, T, Shanzer, A, Sagi, I, Israel Structural Proteomics Center (ISPC) | 登録日 | 2011-11-27 | 公開日 | 2011-12-14 | 最終更新日 | 2017-03-15 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Antibodies targeting the catalytic zinc complex of activated matrix metalloproteinases show therapeutic potential. NAT.MED. (N.Y.), 18, 2012
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4OQ9
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![BU of 4oq9 by Molmil](/molmil-images/mine/4oq9) | Satellite Tobacco Mosaic Virus Refined to 1.4 A Resolution using non-crystallographic symmetry restraints | 分子名称: | Coat protein, MAGNESIUM ION, PHOSPHATE ION, ... | 著者 | Larson, S.B, Day, J.S, McPherson, A. | 登録日 | 2014-02-07 | 公開日 | 2014-09-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Satellite tobacco mosaic virus refined to 1.4 angstrom resolution. Acta Crystallogr.,Sect.D, 70, 2014
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3UCR
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![BU of 3ucr by Molmil](/molmil-images/mine/3ucr) | Crystal structure of the immunoreceptor TIGIT IgV domain | 分子名称: | CHLORIDE ION, T cell immunoreceptor with Ig and ITIM domains | 著者 | Yin, J.P, Stengel, K.F, Rouge, L, Bazan, J.F, Wiesmann, C. | 登録日 | 2011-10-27 | 公開日 | 2012-03-14 | 最終更新日 | 2012-04-25 | 実験手法 | X-RAY DIFFRACTION (2.627 Å) | 主引用文献 | Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering. Proc.Natl.Acad.Sci.USA, 109, 2012
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4OSS
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![BU of 4oss by Molmil](/molmil-images/mine/4oss) | Crystal structure of the S505Q mutant of TAL effector dHax3 | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*CP*AP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*TP*GP*TP*CP*TP*CP*TP*CP*T)-3'), Hax3 | 著者 | Deng, D, Wu, J.P, Yan, C.Y, Pan, X.J, Yan, N. | 登録日 | 2014-02-13 | 公開日 | 2014-05-28 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Revisiting the TALE repeat Protein Cell, 5, 2014
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3UUB
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![BU of 3uub by Molmil](/molmil-images/mine/3uub) | The GLIC pentameric Ligand-Gated Ion Channel Loop2-21' mutant reduced in solution | 分子名称: | CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, DODECYL-BETA-D-MALTOSIDE, ... | 著者 | Sauguet, L, Nury, H, Corringer, P.J, Delarue, M. | 登録日 | 2011-11-28 | 公開日 | 2012-05-16 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A locally closed conformation of a bacterial pentameric proton-gated ion channel. Nat.Struct.Mol.Biol., 19, 2012
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