Summary for 3UMS
| Entry DOI | 10.2210/pdb3ums/pdb |
| Descriptor | Guanine nucleotide-binding protein G(i) subunit alpha-1, GUANOSINE-5'-DIPHOSPHATE, SULFATE ION, ... (5 entities in total) |
| Functional Keywords | gtpase, g-protein, hydrolysis, hydrolase, cell cycle |
| Biological source | Homo sapiens (human) |
| Cellular location | Nucleus (By similarity): P63096 |
| Total number of polymer chains | 1 |
| Total formula weight | 41003.78 |
| Authors | Lambert, N.A.,Johnston, C.A.,Cappell, S.D.,Kuravi, S.,Kimple, A.J.,Willard, F.S.,Siderovski, D.P. (deposition date: 2011-11-14, release date: 2012-02-08, Last modification date: 2023-09-13) |
| Primary citation | Lambert, N.A.,Johnston, C.A.,Cappell, S.D.,Kuravi, S.,Kimple, A.J.,Willard, F.S.,Siderovski, D.P. Correction for Regulators of G-protein Signaling accelerate GPCR signaling kinetics and govern sensitivity solely by accelerating GTPase activity Proc.Natl.Acad.Sci.USA, 2012 Cited by DOI: 10.1073/pnas.1200427109PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.343 Å) |
Structure validation
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