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3UMS

Crystal structure of the G202A mutant of human G-alpha-i1

Replaces:  2PZ2
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(i) subunit alpha-1polymer35440429.11UniProt (P63096)
Pfam (PF00503)
Homo sapiens (human)Adenylate cyclase-inhibiting G alpha protein
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
PubChem (312)
5E
(A)
waterwater18.0126Chemie (HOH)
Sequence modifications
A: 1 - 354 (UniProt: P63096)
PDBExternal DatabaseDetails
Ala 202Gly 202engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight40429.1
Non-Polymers*Number of molecules3
Total formula weight574.7
All*Total formula weight41003.8
*Water molecules are not included.

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PDB entries from 2026-04-01

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