4OP8
Room temperature crystal structure of stabilized TEM-1 beta-lactamase variant v.13 carrying G238S mutation
Summary for 4OP8
| Entry DOI | 10.2210/pdb4op8/pdb |
| Related | 4IBR 4IBX 4OP5 |
| Descriptor | TEM-94 ES-beta-lactamase, CALCIUM ION, TETRAETHYLENE GLYCOL, ... (5 entities in total) |
| Functional Keywords | beta-lactamase, hydrolase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 1 |
| Total formula weight | 29131.17 |
| Authors | Dellus-Gur, E.,Elias, M.,Fraser, J.S.,Tawfik, D.S. (deposition date: 2014-02-05, release date: 2015-05-20, Last modification date: 2023-09-20) |
| Primary citation | Dellus-Gur, E.,Elias, M.,Caselli, E.,Prati, F.,Salverda, M.L.,de Visser, J.A.,Fraser, J.S.,Tawfik, D.S. Negative Epistasis and Evolvability in TEM-1 beta-Lactamase--The Thin Line between an Enzyme's Conformational Freedom and Disorder. J. Mol. Biol., 427:2396-2409, 2015 Cited by PubMed: 26004540DOI: 10.1016/j.jmb.2015.05.011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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