PDB: 19326 件ウェブページステータス検索Chemie searchBIRD

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3H0S	Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7 分子名称: 1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromene-2,4'-piperidin]-4(3H)-one, Acetyl-CoA carboxylase, SULFATE ION 著者 Vajdos, F. 登録日 2009-04-10 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg.Med.Chem.Lett., 20, 2010
3QO0	Monoclinic form of IgG1 Fab fragment (in complex with antigenic peptide) sharing same Fv as IgA 分子名称: Fab fragment of IMMUNOGLOBULIN G1 HEAVY CHAIN, Fab fragment of IMMUNOGLOBULIN G1 LIGHT CHAIN, GLYCEROL, ... 著者 Trajtenberg, F, Correa-Bove, A, Buschiazzo, A. 登録日 2011-02-09 公開日 2012-02-15 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of human IGA1 and IGG1 fab fragments sharing the same variable domains To be published
3H1P	Mature Caspase-7 I213A with DEVD-CHO inhibitor bound to active site 分子名称: Caspase-7, N-ACETYL-L-ALPHA-ASPARTYL-L-ALPHA-GLUTAMYL-N-[(2S)-1-CARBOXY-3-HYDROXYPROPAN-2-YL]-L-VALINAMIDE 著者 Witkowski, W.A, Hardy, J.A. 登録日 2009-04-13 公開日 2009-06-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.61 Å) 主引用文献 L2' loop is critical for caspase-7 active site formation. Protein Sci., 18, 2009
3QTK	The crystal structure of chemically synthesized VEGF-A 分子名称: ACETATE ION, GLYCEROL, Vascular endothelial growth factor A, ... 著者 Mandal, K, Kent, S.B.H. 登録日 2011-02-22 公開日 2011-07-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Total chemical synthesis of biologically active vascular endothelial growth factor. Angew.Chem.Int.Ed.Engl., 50, 2011
3H1V	Human glucokinase in complex with a synthetic activator 分子名称: 1-({5-[4-(methylsulfonyl)phenoxy]-2-pyridin-2-yl-1H-benzimidazol-6-yl}methyl)pyrrolidine-2,5-dione, Glucokinase, SODIUM ION, ... 著者 Kamata, K, Takahashi, K. 登録日 2009-04-14 公開日 2009-10-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 The design and optimization of a series of 2-(pyridin-2-yl)-1H-benzimidazole compounds as allosteric glucokinase activators. Bioorg.Med.Chem., 17, 2009
3QPY	Crystal structure of a mutant (K57A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... 著者 Allison, T.M, Jameson, G.B, Parker, E.J. 登録日 2011-02-14 公開日 2011-04-13 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase Biochemistry, 50, 2011
3QVG	XRCC1 bound to DNA ligase 分子名称: DNA ligase 3, DNA repair protein XRCC1 著者 Cuneo, M.J, Krahn, J.M, London, R.E. 登録日 2011-02-25 公開日 2011-06-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.26 Å) 主引用文献 The structural basis for partitioning of the XRCC1/DNA ligase III-{alpha} BRCT-mediated dimer complexes. Nucleic Acids Res., 39, 2011
3Q6I	Crystal structure of FabG4 and coenzyme binary complex 分子名称: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, 3-oxoacyl-(Acyl-carrier-protein) reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Dutta, D, Bhattacharyya, S, Das, A.K. 登録日 2011-01-01 公開日 2012-01-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.59 Å) 主引用文献 Crystal structure of holoFabG4 To be Published
3ITG	Structure the proline utilization A proline dehydrogenase domain (PutA86-630) inactivated with N-propargylglycine 分子名称: Bifunctional protein putA, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE 著者 Tanner, J.J. 登録日 2009-08-28 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The structure of the proline utilization a proline dehydrogenase domain inactivated by N-propargylglycine provides insight into conformational changes induced by substrate binding and flavin reduction. Biochemistry, 49, 2010
3Q82	Meropenem acylated BlaR1 sensor domain from Staphylococcus aureus 分子名称: (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, Beta-lactamase regulatory protein BlaR1, GLYCEROL 著者 Borbulevych, O.Y, Mobashery, S, Baker, B.M. 登録日 2011-01-05 公開日 2011-07-20 最終更新日 2013-01-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Lysine Nzeta-decarboxylation switch and activation of the beta-lactam sensor domain of BlaR1 protein of methicillin-resistant Staphylococcus aureus. J.Biol.Chem., 286, 2011
3IW5	Human p38 MAP Kinase in Complex with an Indole Derivative 分子名称: Mitogen-activated protein kinase 14, N-[2-(3-{[2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-oxoethyl]sulfanyl}-1H-indol-1-yl)ethyl]-3-(trifluoromethyl)benzamide, octyl beta-D-glucopyranoside 著者 Gruetter, C, Simard, J.R, Rauh, D. 登録日 2009-09-02 公開日 2009-11-17 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 High-Throughput Screening To Identify Inhibitors Which Stabilize Inactive Kinase Conformations in p38alpha J.Am.Chem.Soc., 131, 2009
3IWA	Crystal structure of a FAD-dependent pyridine nucleotide-disulphide oxidoreductase from Desulfovibrio vulgaris 分子名称: CALCIUM ION, FAD-dependent pyridine nucleotide-disulphide oxidoreductase 著者 Bonanno, J.B, Freeman, J, Bain, K.T, Iizuka, M, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) 登録日 2009-09-02 公開日 2009-10-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of a FAD-dependent pyridine nucleotide-disulphide oxidoreductase from Desulfovibrio vulgaris To be Published
3Q7E	Crystal Structure of rat Protein Arginine Methyltransferase 1 (PRMT1)M48L mutant 分子名称: MAGNESIUM ION, Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE 著者 Johnson, S.J, Porter, P.J, Hevel, J.M. 登録日 2011-01-04 公開日 2011-06-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Investigation of the molecular origins of protein-arginine methyltransferase I (PRMT1) product specificity reveals a role for two conserved methionine residues. J.Biol.Chem., 286, 2011
3I6X	Crystal structure of the calponin homology domain of IQGAP1 分子名称: Ras GTPase-activating-like protein IQGAP1 著者 Kurella, V.B. 登録日 2009-07-07 公開日 2010-07-21 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin. Biochemistry, 55, 2016
3Q98	Structure of ygeW encoded protein from E. coli 分子名称: transcarbamylase 著者 Li, Y, Jing, Z, Yu, X, Allewell, N.M, Tuchman, M, Shi, D. 登録日 2011-01-07 公開日 2011-05-04 最終更新日 2018-06-06 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The ygeW encoded protein from Escherichia coli is a knotted ancestral catabolic transcarbamylase. Proteins, 79, 2011
3Q9I	LVFFA segment from Alzheimer's Amyloid-Beta displayed on 42-membered macrocycle scaffold, bromide derivative 分子名称: CHLORIDE ION, Cyclic pseudo-peptide LV(4BF)FA(ORN)(HAO)LK(ORN), GLYCEROL, ... 著者 Liu, C, Sawaya, M.R, Eisenberg, D, Nowick, J.S, Cheng, P, Zheng, J. 登録日 2011-01-07 公開日 2011-06-08 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 Characteristics of Amyloid-Related Oligomers Revealed by Crystal Structures of Macrocyclic beta-Sheet Mimics. J.Am.Chem.Soc., 133, 2011
3Q7U	Structure of Mtb 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD) complexed with CTP 分子名称: 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION 著者 Reddy, M.C.M, Bruning, J.B, Thurman, C, Ioerger, T.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) 登録日 2011-01-05 公開日 2011-05-04 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Mycobacterium tuberculosis 2-C-methyl-D-erythritol 4-phosphate cytidyltransferase (IspD): a candidate antitubercular drug target Proteins, 2011
3I7F	Aspartyl tRNA synthetase from Entamoeba histolytica 分子名称: Aspartyl-tRNA synthetase 著者 Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP) 登録日 2009-07-08 公開日 2009-07-21 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica. Mol.Biochem.Parasitol., 169, 2010
3I7X	High pressure structure of I106A RNase A variant (0.35 GPa) 分子名称: CHLORIDE ION, Ribonuclease pancreatic 著者 Lewinski, K, Kurpiewska, K, Dziubek, K, Katrusiak, A, Font, J, Ribo, M, Vilanova, M. 登録日 2009-07-09 公開日 2009-08-04 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural investigation of ribonuclease A conformational preferences using high pressure protein crystallography Chem.Phys., 468, 2016
3Q8B	Crystal structure of WT Protective Antigen (pH 9.0) 分子名称: CALCIUM ION, Protective antigen 著者 Lovell, S, Battaile, K.P, Rajapaksha, M, Janowiak, B.E, Andra, K.K, Bann, J.G. 登録日 2011-01-06 公開日 2012-02-15 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 pH effects on binding between the anthrax protective antigen and the host cellular receptor CMG2. Protein Sci., 21, 2012
3I87	Ethanolamine Utilization Microcompartment Shell Subunit, EutL Open Form 分子名称: CHLORIDE ION, Ethanolamine utilization protein eutL 著者 Tanaka, S, Sawaya, M.R, Yeates, T.O. 登録日 2009-07-09 公開日 2010-01-12 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and Mechanisms of a Protein-Based Organelle in Escherichia coli. Science, 327, 2010
3QBQ	Crystal structure of extracellular domains of mouse RANK-RANKL complex 分子名称: Tumor necrosis factor ligand superfamily member 11, Tumor necrosis factor receptor superfamily member 11A 著者 Ta, H.M, Nguyen, G.T.T, Jin, H.M, Choi, J.K, Park, H, Kim, N.S, Hwang, H.Y, Kim, K.K. 登録日 2011-01-13 公開日 2011-03-02 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-based development of a receptor activator of nuclear factor-kappaB ligand (RANKL) inhibitor peptide and molecular basis for osteopetrosis Proc.Natl.Acad.Sci.USA, 107, 2010
3QDJ	The complex between TCR DMF5 and human Class I MHC HLA-A2 with the bound MART-1(27-35) nonameric peptide 分子名称: Beta-2-microglobulin, DMF5 alpha chain, DMF5 beta chain, ... 著者 Borbulevych, O.Y, Baker, B.M. 登録日 2011-01-18 公開日 2011-07-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 TCRs Used in Cancer Gene Therapy Cross-React with MART-1/Melan-A Tumor Antigens via Distinct Mechanisms. J.Immunol., 187, 2011
3I8U	Crystal structure of PcyA-181,182-dihydrobiliverdin complex 分子名称: 3-[2-[(Z)-[3-(2-carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-pyrrol-2-ylidene]methy l]-5-[(Z)-(4-ethyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid, Phycocyanobilin:ferredoxin oxidoreductase 著者 Hagiwara, Y, Sugishima, M, Fukuyama, K. 登録日 2009-07-10 公開日 2009-10-27 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structural insights into vinyl reduction regiospecificity of phycocyanobilin:ferredoxin oxidoreductase (PcyA). To be Published
3QC5	GspB 分子名称: GLYCEROL, NITROGEN MOLECULE, POTASSIUM ION, ... 著者 Pyburn, T.M, Iverson, T.M. 登録日 2011-01-15 公開日 2011-08-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors. Plos Pathog., 7, 2011

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