3QPY

Crystal structure of a mutant (K57A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis

Summary for 3QPY

Entry DOI	10.2210/pdb3qpy/pdb
Related	3QPZ 3QQ0 3QQ1
Descriptor	2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, SODIUM ION, ... (5 entities in total)
Functional Keywords	manno-octulosonate, synthase, lipopolysaccharide, kdop, kdo8 kdops, kdo8ps, tim barrel, biosynthesis, transferase, lyase, lipopolysaccharide biosynthesis
Biological source	Neisseria meningitidis
Cellular location	Cytoplasm (By similarity): Q9JZ55
Total number of polymer chains	4
Total formula weight	122066.34
Authors	Allison, T.M.,Jameson, G.B.,Parker, E.J. (deposition date: 2011-02-14, release date: 2011-04-13, Last modification date: 2023-11-01)
Primary citation	Allison, T.M.,Hutton, R.D.,Cochrane, F.C.,Yeoman, J.A.,Jameson, G.B.,Parker, E.J. Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase Biochemistry, 50:3686-3695, 2011 Cited by PubMed: 21438567 DOI: 10.1021/bi200251f PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation