3Q7E

Crystal Structure of rat Protein Arginine Methyltransferase 1 (PRMT1)M48L mutant

Summary for 3Q7E

Entry DOI	10.2210/pdb3q7e/pdb
Descriptor	Protein arginine N-methyltransferase 1, S-ADENOSYL-L-HOMOCYSTEINE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	protein-arginine n-methyltransferases, transferase
Biological source	Rattus norvegicus (brown rat,rat,rats)
Cellular location	Nucleus (By similarity): Q63009
Total number of polymer chains	1
Total formula weight	40783.79
Authors	Johnson, S.J.,Porter, P.J.,Hevel, J.M. (deposition date: 2011-01-04, release date: 2011-06-22, Last modification date: 2023-09-13)
Primary citation	Gui, S.,Wooderchak, W.L.,Daly, M.P.,Porter, P.J.,Johnson, S.J.,Hevel, J.M. Investigation of the molecular origins of protein-arginine methyltransferase I (PRMT1) product specificity reveals a role for two conserved methionine residues. J.Biol.Chem., 286:29118-29126, 2011 Cited by PubMed: 21697082 DOI: 10.1074/jbc.M111.224097 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation