3Q7E
Crystal Structure of rat Protein Arginine Methyltransferase 1 (PRMT1)M48L mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Protein arginine N-methyltransferase 1 | polymer | 349 | 40375.1 | 1 | UniProt (Q63009) Pfam (PF13649) Pfam (PF22528) | Rattus norvegicus (brown rat rat rats) | |
| 2 | B (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 4 | D (A) | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
A: 14 - 353 (UniProt: Q63009)
| PDB | External Database | Details |
|---|---|---|
| Met 5 | - | expression tag |
| Gly 6 | - | expression tag |
| His 7 | - | expression tag |
| His 8 | - | expression tag |
| Asp 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| Met 13 | - | expression tag |
| Leu 48 | Met 48 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40375.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 408.7 | |
| All* | Total formula weight | 40783.8 |
