6O1M
| Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex | 分子名称: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | 著者 | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | 登録日 | 2019-02-20 | 公開日 | 2019-03-13 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Elife, 8, 2019
|
|
2N1K
| |
2MPR
| MALTOPORIN FROM SALMONELLA TYPHIMURIUM | 分子名称: | CALCIUM ION, MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranose | 著者 | Meyer, J.E.W, Schulz, G.E. | 登録日 | 1997-02-07 | 公開日 | 1997-04-01 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of maltoporin from Salmonella typhimurium ligated with a nitrophenyl-maltotrioside. J.Mol.Biol., 266, 1997
|
|
2N2K
| Ensemble structure of the closed state of Lys63-linked diubiquitin in the absence of a ligand | 分子名称: | S-[(1-oxyl-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-3-yl)methyl] methanesulfonothioate, ubiquitin | 著者 | Liu, Z, Gong, Z, Tang, C. | 登録日 | 2015-05-10 | 公開日 | 2015-07-08 | 最終更新日 | 2015-09-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Lys63-linked ubiquitin chain adopts multiple conformational states for specific target recognition. Elife, 4, 2015
|
|
6NNA
| Human Fatty Acid Synthase Psi/KR Tri-Domain with NADPH and Compound 22 | 分子名称: | 1,2-ETHANEDIOL, Fatty acid synthase,Fatty acid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Toms, A.V, Martin, M.W. | 登録日 | 2019-01-14 | 公開日 | 2019-02-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg. Med. Chem. Lett., 29, 2019
|
|
6NQD
| |
2MPZ
| |
2NCH
| |
4OIN
| Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 | 分子名称: | (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... | 著者 | Zhang, Y, Ebright, R.H, Arnold, E. | 登録日 | 2014-01-20 | 公開日 | 2014-05-07 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
|
|
6OD5
| Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence with 5-carboxylcytosines | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DNA (5'-D(*AP*(1CC)P*GP*CP*AP*CP*GP*TP*GP*(1CC)P*G)-3'), ... | 著者 | Horton, J.R, Cheng, X, Yang, J. | 登録日 | 2019-03-25 | 公開日 | 2019-05-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res., 47, 2019
|
|
4MDH
| |
4MEX
| Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | 登録日 | 2013-08-27 | 公開日 | 2014-05-21 | 最終更新日 | 2014-06-25 | 実験手法 | X-RAY DIFFRACTION (3.902 Å) | 主引用文献 | Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
|
|
4LTC
| Crystal structure of yeast 20S proteasome in complex with enone carmaphycin analogue 6 | 分子名称: | N-hexanoyl-L-valyl-N~1~-[(4S,5S,6R)-5-hydroxy-2,6-dimethyloctan-4-yl]-N~5~,N~5~-dimethyl-L-glutamamide, Probable proteasome subunit alpha type-7, Proteasome subunit alpha type-1, ... | 著者 | Stein, M, Trivella, D.B.B, Groll, M. | 登録日 | 2013-07-23 | 公開日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Enzyme inhibition by hydroamination: design and mechanism of a hybrid carmaphycin-syringolin enone proteasome inhibitor. Chem.Biol., 21, 2014
|
|
2NN6
| Structure of the human RNA exosome composed of Rrp41, Rrp45, Rrp46, Rrp43, Mtr3, Rrp42, Csl4, Rrp4, and Rrp40 | 分子名称: | 3'-5' exoribonuclease CSL4 homolog, Exosome complex exonuclease RRP4, Exosome complex exonuclease RRP40, ... | 著者 | Lima, C.D. | 登録日 | 2006-10-23 | 公開日 | 2006-12-26 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Reconstitution, activities, and structure of the eukaryotic RNA exosome. Cell(Cambridge,Mass.), 127, 2006
|
|
2MP4
| Solution Structure of ADF like UNC-60A Protein of Caenorhabditis elegans | 分子名称: | Actin-depolymerizing factor 1, isoforms a/b | 著者 | Shukla, V, Yadav, R, Kabra, A, Kumar, D, Ono, S, Arora, A. | 登録日 | 2014-05-11 | 公開日 | 2014-06-11 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR Structure and Backbone dynamics of ADF like UNC-60A protein from Caenorhabditis elegans: its divergence from conventional ADF/cofilin To be Published
|
|
2N6Z
| |
6N5S
| Structure of Human pir-miRNA-320b-2 Apical Loop and One-base-pair Stem Fused to the YdaO Riboswitch Scaffold | 分子名称: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GUANOSINE-5'-MONOPHOSPHATE, MAGNESIUM ION, ... | 著者 | Shoffner, G.M, Peng, Z, Guo, F. | 登録日 | 2018-11-22 | 公開日 | 2019-11-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.802 Å) | 主引用文献 | Three-dimensional structures of pri-miRNA apical junctions and loops revealed by scaffold-directed crystallography To Be Published
|
|
6OCZ
| Crystal Structure of Mycobacterium tuberculosis Proteasome in Complex with Phenylimidazole-based Inhibitor A86 | 分子名称: | CITRIC ACID, DIMETHYLFORMAMIDE, N-{(2S)-1-({(2S)-1-[(2,4-difluorobenzyl)amino]-1-oxopropan-2-yl}amino)-1,4-dioxo-4-[(2R)-2-phenylpyrrolidin-1-yl]butan-2-yl}-5-methyl-1,2-oxazole-3-carboxamide (non-preferred name), ... | 著者 | Hsu, H.C, Li, H. | 登録日 | 2019-03-25 | 公開日 | 2019-10-09 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Selective Phenylimidazole-Based Inhibitors of theMycobacterium tuberculosisProteasome. J.Med.Chem., 62, 2019
|
|
6OEO
| Cryo-EM structure of mouse RAG1/2 NFC complex (DNA1) | 分子名称: | CALCIUM ION, DNA (46-MER), DNA (57-MER), ... | 著者 | Chen, X, Cui, Y, Zhou, Z.H, Yang, W, Gellert, M. | 登録日 | 2019-03-27 | 公開日 | 2020-01-29 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.69 Å) | 主引用文献 | Cutting antiparallel DNA strands in a single active site. Nat.Struct.Mol.Biol., 27, 2020
|
|
6OFE
| |
6OM1
| Crystal structure of an atypical integrin | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, J.C, Springer, T.A. | 登録日 | 2019-04-17 | 公開日 | 2019-12-11 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | 主引用文献 | General structural features that regulate integrin affinity revealed by atypical alpha V beta 8. Nat Commun, 10, 2019
|
|
6OND
| Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase produced without CooC, reduced | 分子名称: | CHLORIDE ION, Carbon monoxide dehydrogenase, FE (III) ION, ... | 著者 | Wittenborn, E.C, Cohen, S.E, Drennan, C.L. | 登録日 | 2019-04-21 | 公開日 | 2019-07-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.723 Å) | 主引用文献 | Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase. J.Biol.Chem., 294, 2019
|
|
6OHR
| |
2N3J
| Solution Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1 | 分子名称: | Heat shock protein beta-1 | 著者 | Rajagopal, P, Liu, Y, Shi, L, Klevit, R.E. | 登録日 | 2015-06-03 | 公開日 | 2015-08-19 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the alpha-crystallin domain from the redox-sensitive chaperone, HSPB1. J.Biomol.Nmr, 63, 2015
|
|
6OQU
| E. coli ATP synthase State 1d | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | 著者 | Stewart, A.G, Sobti, M, Walshe, J.L. | 登録日 | 2019-04-29 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
|
|